177 related articles for article (PubMed ID: 12729901)
1. Valproic acid, a mood stabilizer and anticonvulsant, protects rat cerebral cortical neurons from spontaneous cell death: a role of histone deacetylase inhibition.
Jeong MR; Hashimoto R; Senatorov VV; Fujimaki K; Ren M; Lee MS; Chuang DM
FEBS Lett; 2003 May; 542(1-3):74-8. PubMed ID: 12729901
[TBL] [Abstract][Full Text] [Related]
2. Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity.
Leng Y; Chuang DM
J Neurosci; 2006 Jul; 26(28):7502-12. PubMed ID: 16837598
[TBL] [Abstract][Full Text] [Related]
3. Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation.
Marinova Z; Ren M; Wendland JR; Leng Y; Liang MH; Yasuda S; Leeds P; Chuang DM
J Neurochem; 2009 Nov; 111(4):976-87. PubMed ID: 19765194
[TBL] [Abstract][Full Text] [Related]
4. Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: roles of glycogen synthase kinase-3 inhibition.
Leng Y; Liang MH; Ren M; Marinova Z; Leeds P; Chuang DM
J Neurosci; 2008 Mar; 28(10):2576-88. PubMed ID: 18322101
[TBL] [Abstract][Full Text] [Related]
5. Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons.
Kanai H; Sawa A; Chen RW; Leeds P; Chuang DM
Pharmacogenomics J; 2004; 4(5):336-44. PubMed ID: 15289798
[TBL] [Abstract][Full Text] [Related]
6. FGF-21, a novel metabolic regulator, has a robust neuroprotective role and is markedly elevated in neurons by mood stabilizers.
Leng Y; Wang Z; Tsai LK; Leeds P; Fessler EB; Wang J; Chuang DM
Mol Psychiatry; 2015 Feb; 20(2):215-23. PubMed ID: 24468826
[TBL] [Abstract][Full Text] [Related]
7. The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons.
Yasuda S; Liang MH; Marinova Z; Yahyavi A; Chuang DM
Mol Psychiatry; 2009 Jan; 14(1):51-9. PubMed ID: 17925795
[TBL] [Abstract][Full Text] [Related]
8. Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen.
Phiel CJ; Zhang F; Huang EY; Guenther MG; Lazar MA; Klein PS
J Biol Chem; 2001 Sep; 276(39):36734-41. PubMed ID: 11473107
[TBL] [Abstract][Full Text] [Related]
9. Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons.
Wu X; Chen PS; Dallas S; Wilson B; Block ML; Wang CC; Kinyamu H; Lu N; Gao X; Leng Y; Chuang DM; Zhang W; Lu RB; Hong JS
Int J Neuropsychopharmacol; 2008 Dec; 11(8):1123-34. PubMed ID: 18611290
[TBL] [Abstract][Full Text] [Related]
10. Valproic acid-mediated neuroprotection in retinal ischemia injury via histone deacetylase inhibition and transcriptional activation.
Zhang Z; Qin X; Tong N; Zhao X; Gong Y; Shi Y; Wu X
Exp Eye Res; 2012 Jan; 94(1):98-108. PubMed ID: 22143029
[TBL] [Abstract][Full Text] [Related]
11. Valproic acid exposure leads to upregulation and increased promoter histone acetylation of sepiapterin reductase in a serotonergic cell line.
Balasubramanian D; Deng AX; Doudney K; Hampton MB; Kennedy MA
Neuropharmacology; 2015 Dec; 99():79-88. PubMed ID: 26151765
[TBL] [Abstract][Full Text] [Related]
12. Valproic acid-mediated neuroprotection in intracerebral hemorrhage via histone deacetylase inhibition and transcriptional activation.
Sinn DI; Kim SJ; Chu K; Jung KH; Lee ST; Song EC; Kim JM; Park DK; Kun Lee S; Kim M; Roh JK
Neurobiol Dis; 2007 May; 26(2):464-72. PubMed ID: 17398106
[TBL] [Abstract][Full Text] [Related]
13. Neuroprotective effects of valproic acid following transient global ischemia in rats.
Xuan A; Long D; Li J; Ji W; Hong L; Zhang M; Zhang W
Life Sci; 2012 Mar; 90(11-12):463-8. PubMed ID: 22285595
[TBL] [Abstract][Full Text] [Related]
14. A proapoptotic effect of valproic acid on progenitors of embryonic stem cell-derived glutamatergic neurons.
Fujiki R; Sato A; Fujitani M; Yamashita T
Cell Death Dis; 2013 Jun; 4(6):e677. PubMed ID: 23788034
[TBL] [Abstract][Full Text] [Related]
15. Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction.
Ren M; Leng Y; Jeong M; Leeds PR; Chuang DM
J Neurochem; 2004 Jun; 89(6):1358-67. PubMed ID: 15189338
[TBL] [Abstract][Full Text] [Related]
16. Valproic acid selectively suppresses the formation of inhibitory synapses in cultured cortical neurons.
Kumamaru E; Egashira Y; Takenaka R; Takamori S
Neurosci Lett; 2014 May; 569():142-7. PubMed ID: 24708928
[TBL] [Abstract][Full Text] [Related]
17. Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity.
Chen PS; Wang CC; Bortner CD; Peng GS; Wu X; Pang H; Lu RB; Gean PW; Chuang DM; Hong JS
Neuroscience; 2007 Oct; 149(1):203-12. PubMed ID: 17850978
[TBL] [Abstract][Full Text] [Related]
18. Induction of neurotrophic and differentiation factors in neural stem cells by valproic acid.
Almutawaa W; Kang NH; Pan Y; Niles LP
Basic Clin Pharmacol Toxicol; 2014 Aug; 115(2):216-21. PubMed ID: 24460582
[TBL] [Abstract][Full Text] [Related]
19. Valproic acid inhibits neurosphere formation by adult subventricular cells by a lithium-sensitive mechanism.
Zhou Q; Dalgard CL; Wynder C; Doughty ML
Neurosci Lett; 2011 Aug; 500(3):202-6. PubMed ID: 21741439
[TBL] [Abstract][Full Text] [Related]
20. Prevention of hypoxia-induced neuronal apoptosis through histone deacetylase inhibition.
Li Y; Yuan Z; Liu B; Sailhamer EA; Shults C; Velmahos GC; Demoya M; Alam HB
J Trauma; 2008 Apr; 64(4):863-70; discussion 870-1. PubMed ID: 18404049
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
