446 related articles for article (PubMed ID: 12732733)
1. Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex.
Brzovic PS; Keeffe JR; Nishikawa H; Miyamoto K; Fox D; Fukuda M; Ohta T; Klevit R
Proc Natl Acad Sci U S A; 2003 May; 100(10):5646-51. PubMed ID: 12732733
[TBL] [Abstract][Full Text] [Related]
2. Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein.
Xia Y; Pao GM; Chen HW; Verma IM; Hunter T
J Biol Chem; 2003 Feb; 278(7):5255-63. PubMed ID: 12431996
[TBL] [Abstract][Full Text] [Related]
3. The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity.
Baer R; Ludwig T
Curr Opin Genet Dev; 2002 Feb; 12(1):86-91. PubMed ID: 11790560
[TBL] [Abstract][Full Text] [Related]
4. The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation.
Hashizume R; Fukuda M; Maeda I; Nishikawa H; Oyake D; Yabuki Y; Ogata H; Ohta T
J Biol Chem; 2001 May; 276(18):14537-40. PubMed ID: 11278247
[TBL] [Abstract][Full Text] [Related]
5. Structure of a BRCA1-BARD1 heterodimeric RING-RING complex.
Brzovic PS; Rajagopal P; Hoyt DW; King MC; Klevit RE
Nat Struct Biol; 2001 Oct; 8(10):833-7. PubMed ID: 11573085
[TBL] [Abstract][Full Text] [Related]
6. Nuclear-cytoplasmic shuttling of BARD1 contributes to its proapoptotic activity and is regulated by dimerization with BRCA1.
Rodriguez JA; Schüchner S; Au WW; Fabbro M; Henderson BR
Oncogene; 2004 Mar; 23(10):1809-20. PubMed ID: 14647430
[TBL] [Abstract][Full Text] [Related]
7. Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains.
Mallery DL; Vandenberg CJ; Hiom K
EMBO J; 2002 Dec; 21(24):6755-62. PubMed ID: 12485996
[TBL] [Abstract][Full Text] [Related]
8. Mass spectrometric and mutational analyses reveal Lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligase.
Nishikawa H; Ooka S; Sato K; Arima K; Okamoto J; Klevit RE; Fukuda M; Ohta T
J Biol Chem; 2004 Feb; 279(6):3916-24. PubMed ID: 14638690
[TBL] [Abstract][Full Text] [Related]
9. Autoubiquitination of the BRCA1*BARD1 RING ubiquitin ligase.
Chen A; Kleiman FE; Manley JL; Ouchi T; Pan ZQ
J Biol Chem; 2002 Jun; 277(24):22085-92. PubMed ID: 11927591
[TBL] [Abstract][Full Text] [Related]
10. The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin.
Wu-Baer F; Lagrazon K; Yuan W; Baer R
J Biol Chem; 2003 Sep; 278(37):34743-6. PubMed ID: 12890688
[TBL] [Abstract][Full Text] [Related]
11. A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-directed ubiquitination.
Brzovic PS; Lissounov A; Christensen DE; Hoyt DW; Klevit RE
Mol Cell; 2006 Mar; 21(6):873-80. PubMed ID: 16543155
[TBL] [Abstract][Full Text] [Related]
12. The BRCA1/BARD1 ubiquitin ligase and its substrates.
Witus SR; Stewart MD; Klevit RE
Biochem J; 2021 Sep; 478(18):3467-3483. PubMed ID: 34591954
[TBL] [Abstract][Full Text] [Related]
13. Mapping the functional domains of BRCA1. Interaction of the ring finger domains of BRCA1 and BARD1.
Meza JE; Brzovic PS; King MC; Klevit RE
J Biol Chem; 1999 Feb; 274(9):5659-65. PubMed ID: 10026184
[TBL] [Abstract][Full Text] [Related]
14. Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity.
Ruffner H; Joazeiro CA; Hemmati D; Hunter T; Verma IM
Proc Natl Acad Sci U S A; 2001 Apr; 98(9):5134-9. PubMed ID: 11320250
[TBL] [Abstract][Full Text] [Related]
15. Identification of a RING protein that can interact in vivo with the BRCA1 gene product.
Wu LC; Wang ZW; Tsan JT; Spillman MA; Phung A; Xu XL; Yang MC; Hwang LY; Bowcock AM; Baer R
Nat Genet; 1996 Dec; 14(4):430-40. PubMed ID: 8944023
[TBL] [Abstract][Full Text] [Related]
16. Control of biochemical reactions through supramolecular RING domain self-assembly.
Kentsis A; Gordon RE; Borden KL
Proc Natl Acad Sci U S A; 2002 Nov; 99(24):15404-9. PubMed ID: 12438698
[TBL] [Abstract][Full Text] [Related]
17. Negative feedback loop of BRCA1-BARD1 ubiquitin ligase on estrogen receptor alpha stability and activity antagonized by cancer-associated isoform of BARD1.
Dizin E; Irminger-Finger I
Int J Biochem Cell Biol; 2010 May; 42(5):693-700. PubMed ID: 20060929
[TBL] [Abstract][Full Text] [Related]
18. Tuning BRCA1 and BARD1 activity to investigate RING ubiquitin ligase mechanisms.
Stewart MD; Duncan ED; Coronado E; DaRosa PA; Pruneda JN; Brzovic PS; Klevit RE
Protein Sci; 2017 Mar; 26(3):475-483. PubMed ID: 27977889
[TBL] [Abstract][Full Text] [Related]
19. Estrogen receptor alpha is a putative substrate for the BRCA1 ubiquitin ligase.
Eakin CM; Maccoss MJ; Finney GL; Klevit RE
Proc Natl Acad Sci U S A; 2007 Apr; 104(14):5794-9. PubMed ID: 17392432
[TBL] [Abstract][Full Text] [Related]
20. Conservation of function and primary structure in the BRCA1-associated RING domain (BARD1) protein.
Ayi TC; Tsan JT; Hwang LY; Bowcock AM; Baer R
Oncogene; 1998 Oct; 17(16):2143-8. PubMed ID: 9798686
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]