These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 12735696)

  • 1. Current mechanistic understanding of thiamin diphosphate-dependent enzymatic reactions.
    Jordan F
    Nat Prod Rep; 2003 Apr; 20(2):184-201. PubMed ID: 12735696
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of thiamin diphosphate in enzymes.
    Hübner G; Tittmann K; Killenberg-Jabs M; Schäffner J; Spinka M; Neef H; Kern D; Kern G; Schneider G; Wikner C; Ghisla S
    Biochim Biophys Acta; 1998 Jun; 1385(2):221-8. PubMed ID: 9655909
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tetrahedral intermediates in thiamin diphosphate-dependent decarboxylations exist as a 1',4'-imino tautomeric form of the coenzyme, unlike the michaelis complex or the free coenzyme.
    Nemeria N; Baykal A; Joseph E; Zhang S; Yan Y; Furey W; Jordan F
    Biochemistry; 2004 Jun; 43(21):6565-75. PubMed ID: 15157089
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of thiamin diphosphate-dependent 2-oxo acid decarboxylases by substrate and thiamin diphosphate.Mg(II) - evidence for tertiary and quaternary interactions.
    Jordan F; Nemeria N; Guo F; Baburina I; Gao Y; Kahyaoglu A; Li H; Wang J; Yi J; Guest JR; Furey W
    Biochim Biophys Acta; 1998 Jun; 1385(2):287-306. PubMed ID: 9655921
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interplay of organic and biological chemistry in understanding coenzyme mechanisms: example of thiamin diphosphate-dependent decarboxylations of 2-oxo acids.
    Jordan F
    FEBS Lett; 1999 Sep; 457(3):298-301. PubMed ID: 10471796
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bifunctionality of the thiamin diphosphate cofactor: assignment of tautomeric/ionization states of the 4'-aminopyrimidine ring when various intermediates occupy the active sites during the catalysis of yeast pyruvate decarboxylase.
    Balakrishnan A; Gao Y; Moorjani P; Nemeria NS; Tittmann K; Jordan F
    J Am Chem Soc; 2012 Feb; 134(8):3873-85. PubMed ID: 22300533
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dual catalytic apparatus of the thiamin diphosphate coenzyme: acid-base via the 1',4'-iminopyrimidine tautomer along with its electrophilic role.
    Jordan F; Nemeria NS; Zhang S; Yan Y; Arjunan P; Furey W
    J Am Chem Soc; 2003 Oct; 125(42):12732-8. PubMed ID: 14558820
    [TBL] [Abstract][Full Text] [Related]  

  • 8. C2-alpha-lactylthiamin diphosphate is an intermediate on the pathway of thiamin diphosphate-dependent pyruvate decarboxylation. Evidence on enzymes and models.
    Zhang S; Liu M; Yan Y; Zhang Z; Jordan F
    J Biol Chem; 2004 Dec; 279(52):54312-8. PubMed ID: 15501823
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The 1',4'-iminopyrimidine tautomer of thiamin diphosphate is poised for catalysis in asymmetric active centers on enzymes.
    Nemeria N; Chakraborty S; Baykal A; Korotchkina LG; Patel MS; Jordan F
    Proc Natl Acad Sci U S A; 2007 Jan; 104(1):78-82. PubMed ID: 17182735
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thiamin-diphosphate-dependent enzymes: new aspects of asymmetric C-C bond formation.
    Pohl M; Lingen B; Müller M
    Chemistry; 2002 Dec; 8(23):5288-95. PubMed ID: 12432496
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Specificity of coenzyme binding in thiamin diphosphate-dependent enzymes. Crystal structures of yeast transketolase in complex with analogs of thiamin diphosphate.
    König S; Schellenberger A; Neef H; Schneider G
    J Biol Chem; 1994 Apr; 269(14):10879-82. PubMed ID: 8144674
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Is a hydrophobic amino acid required to maintain the reactive V conformation of thiamin at the active center of thiamin diphosphate-requiring enzymes? Experimental and computational studies of isoleucine 415 of yeast pyruvate decarboxylase.
    Guo F; Zhang D; Kahyaoglu A; Farid RS; Jordan F
    Biochemistry; 1998 Sep; 37(38):13379-91. PubMed ID: 9748345
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Catalytic centers in the thiamin diphosphate dependent enzyme pyruvate decarboxylase at 2.4-A resolution.
    Dyda F; Furey W; Swaminathan S; Sax M; Farrenkopf B; Jordan F
    Biochemistry; 1993 Jun; 32(24):6165-70. PubMed ID: 8512926
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Progress in the experimental observation of thiamin diphosphate-bound intermediates on enzymes and mechanistic information derived from these observations.
    Jordan F; Nemeria NS
    Bioorg Chem; 2014 Dec; 57():251-262. PubMed ID: 25228115
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reaction mechanisms of thiamin diphosphate enzymes: defining states of ionization and tautomerization of the cofactor at individual steps.
    Nemeria NS; Chakraborty S; Balakrishnan A; Jordan F
    FEBS J; 2009 May; 276(9):2432-46. PubMed ID: 19476485
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Theoretical Studies of the Electronic Absorption Spectra of Thiamin Diphosphate in Pyruvate Decarboxylase.
    Paulikat M; Wechsler C; Tittmann K; Mata RA
    Biochemistry; 2017 Apr; 56(13):1854-1864. PubMed ID: 28296385
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A thiamin diphosphate binding fold revealed by comparison of the crystal structures of transketolase, pyruvate oxidase and pyruvate decarboxylase.
    Muller YA; Lindqvist Y; Furey W; Schulz GE; Jordan F; Schneider G
    Structure; 1993 Oct; 1(2):95-103. PubMed ID: 8069629
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure and properties of pyruvate decarboxylase and site-directed mutagenesis of the Zymomonas mobilis enzyme.
    Candy JM; Duggleby RG
    Biochim Biophys Acta; 1998 Jun; 1385(2):323-38. PubMed ID: 9655927
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thiamin diphosphate in biological chemistry: analogues of thiamin diphosphate in studies of enzymes and riboswitches.
    Agyei-Owusu K; Leeper FJ
    FEBS J; 2009 Jun; 276(11):2905-16. PubMed ID: 19490097
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 2-Oxo-3-alkynoic acids, universal mechanism-based inactivators of thiamin diphosphate-dependent decarboxylases: synthesis and evidence for potent inactivation of the pyruvate dehydrogenase multienzyme complex.
    Brown A; Nemeria N; Yi J; Zhang D; Jordan WB; Machado RS; Guest JR; Jordan F
    Biochemistry; 1997 Jul; 36(26):8071-81. PubMed ID: 9201955
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.