BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 12739231)

  • 1. Relationship between expression of O6-methylguanine-DNA methyltransferase, glutathione-S-transferase pi in glioblastoma and the survival of the patients treated with nimustine hydrochloride: an immunohistochemical analysis.
    Anda T; Shabani HK; Tsunoda K; Tokunaga Y; Kaminogo M; Shibata S; Hayashi T; Iseki M
    Neurol Res; 2003 Apr; 25(3):241-8. PubMed ID: 12739231
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Correlation between promoter hypermethylation of the O6-methylguanine-deoxyribonucleic acid methyltransferase gene and prognosis in patients with high-grade astrocytic tumors treated with surgery, radiotherapy, and 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea-based chemotherapy.
    Kamiryo T; Tada K; Shiraishi S; Shinojima N; Kochi M; Ushio Y
    Neurosurgery; 2004 Feb; 54(2):349-57; discussion 357. PubMed ID: 14744281
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Prognostic significance of O6-methylguanine-DNA methyltransferase protein expression in patients with recurrent glioblastoma treated with temozolomide.
    Nagane M; Kobayashi K; Ohnishi A; Shimizu S; Shiokawa Y
    Jpn J Clin Oncol; 2007 Dec; 37(12):897-906. PubMed ID: 18156172
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Study on potentiation of nitrosourea-cytotoxicity by DNA repair enzyme inhibitors in human brain tumor cells].
    Fukuchi M; Mineura K; Kowada M; Terashima I; Kohda K
    No To Shinkei; 1997 Jun; 49(6):521-8. PubMed ID: 9198092
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Induction of the DNA repair gene O6-methylguanine-DNA methyltransferase by dexamethasone in glioblastomas.
    Ueda S; Mineta T; Nakahara Y; Okamoto H; Shiraishi T; Tabuchi K
    J Neurosurg; 2004 Oct; 101(4):659-63. PubMed ID: 15481722
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prognostic significance of the immunohistochemical expression of O6-methylguanine-DNA methyltransferase, P-glycoprotein, and multidrug resistance protein-1 in glioblastomas.
    Nakagawa T; Ido K; Sakuma T; Takeuchi H; Sato K; Kubota T
    Neuropathology; 2009 Aug; 29(4):379-88. PubMed ID: 19019175
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Immunohistochemical evaluation of O6 -methylguanine DNA methyltransferase (MGMT) expression in 117 cases of glioblastoma.
    Miyazaki M; Nishihara H; Terasaka S; Kobayashi H; Yamaguchi S; Ito T; Kamoshima Y; Fujimoto S; Kaneko S; Katoh M; Ishii N; Mohri H; Tanino M; Kimura T; Tanaka S
    Neuropathology; 2014 Jun; 34(3):268-76. PubMed ID: 24397721
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Randomized trial of chemoradiotherapy and adjuvant chemotherapy with nimustine (ACNU) versus nimustine plus procarbazine for newly diagnosed anaplastic astrocytoma and glioblastoma (JCOG0305).
    Shibui S; Narita Y; Mizusawa J; Beppu T; Ogasawara K; Sawamura Y; Kobayashi H; Nishikawa R; Mishima K; Muragaki Y; Maruyama T; Kuratsu J; Nakamura H; Kochi M; Minamida Y; Yamaki T; Kumabe T; Tominaga T; Kayama T; Sakurada K; Nagane M; Kobayashi K; Nakamura H; Ito T; Yazaki T; Sasaki H; Tanaka K; Takahashi H; Asai A; Todo T; Wakabayashi T; Takahashi J; Takano S; Fujimaki T; Sumi M; Miyakita Y; Nakazato Y; Sato A; Fukuda H; Nomura K
    Cancer Chemother Pharmacol; 2013 Feb; 71(2):511-21. PubMed ID: 23228988
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cisplatin represses transcriptional activity from the minimal promoter of the O6-methylguanine methyltransferase gene and increases sensitivity of human gallbladder cancer cells to 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-2-chloroethyl)-3-nitrosourea.
    Sato K; Kitajima Y; Nakagawachi T; Soejima H; Miyoshi A; Koga Y; Miyazaki K
    Oncol Rep; 2005 May; 13(5):899-906. PubMed ID: 15809756
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prognostic impact of O6-methylguanine-DNA methyltransferase silencing in patients with recurrent glioblastoma multiforme who undergo surgery and carmustine wafer implantation: a prospective patient cohort.
    Metellus P; Coulibaly B; Nanni I; Fina F; Eudes N; Giorgi R; Barrie M; Chinot O; Fuentes S; Dufour H; Ouafik L; Figarella-Branger D
    Cancer; 2009 Oct; 115(20):4783-94. PubMed ID: 19637364
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The effect of o6-methylguanine-DNA methyltransferase (MGMT) and mismatch repair gene (hMLH1) status on the sensitivity to alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea(ACNU) in gallbladder carcinoma cells.
    Sato K; Kitajima Y; Koga Y; Miyazaki K
    Anticancer Res; 2005; 25(6B):4021-8. PubMed ID: 16309194
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of O6-methylguanine-DNA methyltransferase in the resistance of pancreatic tumors to DNA alkylating agents.
    Kokkinakis DM; Ahmed MM; Delgado R; Fruitwala MM; Mohiuddin M; Albores-Saavedra J
    Cancer Res; 1997 Dec; 57(23):5360-8. PubMed ID: 9393761
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Investigation of chemoresistance-related genes mRNA expression for selecting anticancer agents in successful adjuvant chemotherapy for a case of recurrent glioblastoma.
    Nagane M; Shibui S; Oyama H; Asai A; Kuchino Y; Nomura K
    Surg Neurol; 1995 Nov; 44(5):462-8; discussion 468-70. PubMed ID: 8629231
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Preliminary individual adjuvant therapy for gliomas based on the results of molecular biological analyses for drug-resistance genes.
    Tanaka S; Kamitani H; Amin MR; Watanabe T; Oka H; Fujii K; Nagashima T; Hori T
    J Neurooncol; 2000; 46(2):157-71. PubMed ID: 10894369
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Down-regulation of O6-methylguanine-DNA methyltransferase gene expression in gliomas by platinum compounds.
    Tanaka S; Kobayashi I; Utsuki S; Oka H; Yasui Y; Fujii K
    Oncol Rep; 2005 Nov; 14(5):1275-80. PubMed ID: 16211296
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Methylation status of the MGMT gene promoter fails to predict the clinical outcome of glioblastoma patients treated with ACNU plus cisplatin.
    Park CK; Park SH; Lee SH; Kim CY; Kim DW; Paek SH; Kim DG; Heo DS; Kim IH; Jung HW
    Neuropathology; 2009 Aug; 29(4):443-9. PubMed ID: 19170894
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression of O6-methylguanine-DNA methyltransferase and chloroethylnitrosourea resistance of human brain tumors.
    Nagane M; Asai A; Shibui S; Nomura K; Matsutani M; Kuchino Y
    Jpn J Clin Oncol; 1992 Jun; 22(3):143-9. PubMed ID: 1518162
    [TBL] [Abstract][Full Text] [Related]  

  • 18. O6-methyl-guanine-DNA methyltransferase methylation in serum and tumor DNA predicts response to 1,3-bis(2-chloroethyl)-1-nitrosourea but not to temozolamide plus cisplatin in glioblastoma multiforme.
    BalaƱa C; Ramirez JL; Taron M; Roussos Y; Ariza A; Ballester R; Sarries C; Mendez P; Sanchez JJ; Rosell R
    Clin Cancer Res; 2003 Apr; 9(4):1461-8. PubMed ID: 12684420
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modulation of O6-methylguanine-DNA methyltransferase-mediated 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea resistance by O6-benzylguanine in vitro and in vivo.
    Chen JM; Zhang YP; Sui JL; Moschel RC; Ikenaga M
    Anticancer Res; 1993; 13(3):801-5. PubMed ID: 8317915
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential expression of drug resistance genes and chemosensitivity in glial cell lineages correlate with differential response of oligodendrogliomas and astrocytomas to chemotherapy.
    Nutt CL; Noble M; Chambers AF; Cairncross JG
    Cancer Res; 2000 Sep; 60(17):4812-8. PubMed ID: 10987291
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.