BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 12740857)

  • 1. Diastereoselective solution and multipin-based combinatorial array synthesis of a novel class of potent phosphinic metalloprotease inhibitors.
    Makaritis A; Georgiadis D; Dive V; Yiotakis A
    Chemistry; 2003 May; 9(9):2079-94. PubMed ID: 12740857
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evaluation of P1'-diversified phosphinic peptides leads to the development of highly selective inhibitors of MMP-11.
    Matziari M; Beau F; Cuniasse P; Dive V; Yiotakis A
    J Med Chem; 2004 Jan; 47(2):325-36. PubMed ID: 14711305
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Active methylene phosphinic peptides: a new diversification approach.
    Matziari M; Nasopoulou M; Yiotakis A
    Org Lett; 2006 May; 8(11):2317-9. PubMed ID: 16706515
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphinic pseudo-tripeptides as potent inhibitors of matrix metalloproteinases: a structure-activity study.
    Vassiliou S; Mucha A; Cuniasse P; Georgiadis D; Lucet-Levannier K; Beau F; Kannan R; Murphy G; Knäuper V; Rio MC; Basset P; Yiotakis A; Dive V
    J Med Chem; 1999 Jul; 42(14):2610-20. PubMed ID: 10411481
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and activity of phosphinic tripeptide inhibitors of cathepsin C.
    Mucha A; Paweł M; Hurek J; Kafarski P
    Bioorg Med Chem Lett; 2004 Jun; 14(12):3113-6. PubMed ID: 15149655
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of the phosphinic analogue of thyrotropin releasing hormone.
    Matziari M; Bauer K; Dive V; Yiotakis A
    J Org Chem; 2008 Nov; 73(21):8591-3. PubMed ID: 18826326
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of highly potent and selective phosphinic peptide inhibitors of zinc endopeptidase 24-15 using combinatorial chemistry.
    Jirácek J; Yiotakis A; Vincent B; Lecoq A; Nicolaou A; Checler F; Dive V
    J Biol Chem; 1995 Sep; 270(37):21701-6. PubMed ID: 7665587
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A versatile annulation protocol toward novel constrained phosphinic peptidomimetics.
    Nasopoulou M; Georgiadis D; Matziari M; Dive V; Yiotakis A
    J Org Chem; 2007 Sep; 72(19):7222-8. PubMed ID: 17715974
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A convergent solution-phase synthesis of the macrocycle Ac-Phe-[Orn-Pro-D-Cha-Trp-Arg], a potent new antiinflammatory drug.
    Reid RC; Abbenante G; Taylor SM; Fairlie DP
    J Org Chem; 2003 May; 68(11):4464-71. PubMed ID: 12762752
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphinic acid-based MMP-13 inhibitors that spare MMP-1 and MMP-3.
    Reiter LA; Mitchell PG; Martinelli GJ; Lopresti-Morrow LL; Yocum SA; Eskra JD
    Bioorg Med Chem Lett; 2003 Jul; 13(14):2331-6. PubMed ID: 12824028
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel hydroxamic acid-related phosphinates: inhibition of neutral aminopeptidase N (APN).
    Drag M; Grzywa R; Oleksyszyn J
    Bioorg Med Chem Lett; 2007 Mar; 17(6):1516-9. PubMed ID: 17270439
    [TBL] [Abstract][Full Text] [Related]  

  • 12. alpha-Biphenylsulfonylamino 2-methylpropyl phosphonates: enantioselective synthesis and selective inhibition of MMPs.
    Biasone A; Tortorella P; Campestre C; Agamennone M; Preziuso S; Chiappini M; Nuti E; Carelli P; Rossello A; Mazza F; Gallina C
    Bioorg Med Chem; 2007 Jan; 15(2):791-9. PubMed ID: 17088065
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and metal binding of novel Pseudo- oligopeptides containing two phosphinic acid groups.
    Ye Y; Liu M; Kao JL; Marshall GR
    Biopolymers; 2008 Jan; 89(1):72-85. PubMed ID: 17910046
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of the first potent and selective inhibitor of the zinc endopeptidase neurolysin using a systematic approach based on combinatorial chemistry of phosphinic peptides.
    Jirácek J; Yiotakis A; Vincent B; Checler F; Dive V
    J Biol Chem; 1996 Aug; 271(32):19606-11. PubMed ID: 8702656
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Shortcut to fmoc-protected phosphinic pseudodipeptidic blocks.
    Matziari M; Yiotakis A
    Org Lett; 2005 Sep; 7(18):4049-52. PubMed ID: 16119964
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chemoselective protection of solid-phase compatible Fmoc-phosphinic building blocks.
    Nasopoulou M; Matziari M; Dive V; Yiotakis A
    J Org Chem; 2006 Dec; 71(25):9525-7. PubMed ID: 17137389
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Diastereoselective synthesis of alpha,beta'-disubstituted aminomethyl(2-carboxyethyl)phosphinates as phosphinyl dipeptide isosteres.
    Yamagishi T; Ichikawa H; Haruki T; Yokomatsu T
    Org Lett; 2008 Oct; 10(19):4347-50. PubMed ID: 18781768
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Solid-phase synthesis of succinylhydroxamate peptides: functionalized matrix metalloproteinase inhibitors.
    Leeuwenburgh MA; Geurink PP; Klein T; Kauffman HF; van der Marel GA; Bischoff R; Overkleeft HS
    Org Lett; 2006 Apr; 8(8):1705-8. PubMed ID: 16597146
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel method for the separation of bis(alpha-hydroxyalkyl)phosphinic acid diastereoisomers via formation of novel cyclic phosphinic acids.
    Kaboudin B; Haghighat H; Yokomatsu T
    J Org Chem; 2006 Aug; 71(17):6604-6. PubMed ID: 16901151
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Conformational and solvation studies via computer simulation of the novel large scale diastereoselectively synthesized phosphinic MMP inhibitor RXP03 diluted in selected solvents.
    Matziari M; Dellis D; Dive V; Yiotakis A; Samios J
    J Phys Chem B; 2010 Jan; 114(1):421-8. PubMed ID: 20014753
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.