BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

106 related articles for article (PubMed ID: 12743600)

  • 1. Random mutagenesis of PDZ(Omi) domain and selection of mutants that specifically bind the Myc proto-oncogene and induce apoptosis.
    Junqueira D; Cilenti L; Musumeci L; Sedivy JM; Zervos AS
    Oncogene; 2003 May; 22(18):2772-81. PubMed ID: 12743600
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi.
    Li W; Srinivasula SM; Chai J; Li P; Wu JW; Zhang Z; Alnemri ES; Shi Y
    Nat Struct Biol; 2002 Jun; 9(6):436-41. PubMed ID: 11967569
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tissue-specific splicing of Omi stress-regulated endoprotease leads to an inactive protease with a modified PDZ motif.
    Faccio L; Fusco C; Viel A; Zervos AS
    Genomics; 2000 Sep; 68(3):343-7. PubMed ID: 10995577
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mitochondrial protease Omi/HtrA2 enhances caspase activation through multiple pathways.
    Suzuki Y; Takahashi-Niki K; Akagi T; Hashikawa T; Takahashi R
    Cell Death Differ; 2004 Feb; 11(2):208-16. PubMed ID: 14605674
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice.
    Jones JM; Datta P; Srinivasula SM; Ji W; Gupta S; Zhang Z; Davies E; Hajnóczky G; Saunders TL; Van Keuren ML; Fernandes-Alnemri T; Meisler MH; Alnemri ES
    Nature; 2003 Oct; 425(6959):721-7. PubMed ID: 14534547
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Specific protein interaction of human Pag with Omi/HtrA2 and the activation of the protease activity of Omi/HtrA2.
    Hong SK; Cha MK; Kim IH
    Free Radic Biol Med; 2006 Jan; 40(2):275-84. PubMed ID: 16413409
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity.
    van Loo G; van Gurp M; Depuydt B; Srinivasula SM; Rodriguez I; Alnemri ES; Gevaert K; Vandekerckhove J; Declercq W; Vandenabeele P
    Cell Death Differ; 2002 Jan; 9(1):20-6. PubMed ID: 11803371
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Serine protease Omi/HtrA2 targets WARTS kinase to control cell proliferation.
    Kuninaka S; Iida SI; Hara T; Nomura M; Naoe H; Morisaki T; Nitta M; Arima Y; Mimori T; Yonehara S; Saya H
    Oncogene; 2007 Apr; 26(17):2395-406. PubMed ID: 17130845
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The mitochondrial serine protease HtrA2/Omi: an overview.
    Vande Walle L; Lamkanfi M; Vandenabeele P
    Cell Death Differ; 2008 Mar; 15(3):453-60. PubMed ID: 18174901
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rapid characterization of the binding property of HtrA2/Omi PDZ domain by validation screening of PDZ ligand library.
    Ma S; Song E; Gao S; Tian R; Gao Y
    Sci China C Life Sci; 2007 Jun; 50(3):412-22. PubMed ID: 17609899
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alzheimer's disease-associated amyloid beta interacts with the human serine protease HtrA2/Omi.
    Park HJ; Seong YM; Choi JY; Kang S; Rhim H
    Neurosci Lett; 2004 Feb; 357(1):63-7. PubMed ID: 15036614
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutagenesis and selection of PDZ domains that bind new protein targets.
    Schneider S; Buchert M; Georgiev O; Catimel B; Halford M; Stacker SA; Baechi T; Moelling K; Hovens CM
    Nat Biotechnol; 1999 Feb; 17(2):170-5. PubMed ID: 10052354
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dispensable PDZ domain of Escherichia coli YaeL essential protease.
    Bohn C; Collier J; Bouloc P
    Mol Microbiol; 2004 Apr; 52(2):427-35. PubMed ID: 15066031
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mitochondrial import of Omi: the definitive role of the putative transmembrane region and multiple processing sites in the amino-terminal segment.
    Kadomatsu T; Mori M; Terada K
    Biochem Biophys Res Commun; 2007 Sep; 361(2):516-21. PubMed ID: 17662244
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice.
    Martins LM; Morrison A; Klupsch K; Fedele V; Moisoi N; Teismann P; Abuin A; Grau E; Geppert M; Livi GP; Creasy CL; Martin A; Hargreaves I; Heales SJ; Okada H; Brandner S; Schulz JB; Mak T; Downward J
    Mol Cell Biol; 2004 Nov; 24(22):9848-62. PubMed ID: 15509788
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Omi is a mammalian heat-shock protein that selectively binds and detoxifies oligomeric amyloid-beta.
    Liu ML; Liu MJ; Shen YF; Ryu H; Kim HJ; Klupsch K; Downward J; Hong ST
    J Cell Sci; 2009 Jun; 122(Pt 11):1917-26. PubMed ID: 19435805
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural and functional analysis of the ligand specificity of the HtrA2/Omi PDZ domain.
    Zhang Y; Appleton BA; Wu P; Wiesmann C; Sidhu SS
    Protein Sci; 2007 Aug; 16(8):1738-50. PubMed ID: 17656586
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi.
    Martins LM; Turk BE; Cowling V; Borg A; Jarrell ET; Cantley LC; Downward J
    J Biol Chem; 2003 Dec; 278(49):49417-27. PubMed ID: 14512424
    [TBL] [Abstract][Full Text] [Related]  

  • 19. AtBAG6, a novel calmodulin-binding protein, induces programmed cell death in yeast and plants.
    Kang CH; Jung WY; Kang YH; Kim JY; Kim DG; Jeong JC; Baek DW; Jin JB; Lee JY; Kim MO; Chung WS; Mengiste T; Koiwa H; Kwak SS; Bahk JD; Lee SY; Nam JS; Yun DJ; Cho MJ
    Cell Death Differ; 2006 Jan; 13(1):84-95. PubMed ID: 16003391
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The serine protease Omi/HtrA2 is involved in XIAP cleavage and in neuronal cell death following focal cerebral ischemia/reperfusion.
    Althaus J; Siegelin MD; Dehghani F; Cilenti L; Zervos AS; Rami A
    Neurochem Int; 2007 Jan; 50(1):172-80. PubMed ID: 16978742
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.