BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 12746453)

  • 1. Cyclin D1 splice variants. Differential effects on localization, RB phosphorylation, and cellular transformation.
    Solomon DA; Wang Y; Fox SR; Lambeck TC; Giesting S; Lan Z; Senderowicz AM; Conti CJ; Knudsen ES
    J Biol Chem; 2003 Aug; 278(32):30339-47. PubMed ID: 12746453
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cyclin D1b variant promotes cell invasiveness independent of binding to CDK4 in human bladder cancer cells.
    Kim CJ; Nishi K; Isono T; Okuyama Y; Tambe Y; Okada Y; Inoue H
    Mol Carcinog; 2009 Oct; 48(10):953-64. PubMed ID: 19415719
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An alternatively spliced cyclin D1 isoform, cyclin D1b, is a nuclear oncogene.
    Lu F; Gladden AB; Diehl JA
    Cancer Res; 2003 Nov; 63(21):7056-61. PubMed ID: 14612495
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Critical role of cyclin D1 nuclear import in cardiomyocyte proliferation.
    Tamamori-Adachi M; Ito H; Sumrejkanchanakij P; Adachi S; Hiroe M; Shimizu M; Kawauchi J; Sunamori M; Marumo F; Kitajima S; Ikeda MA
    Circ Res; 2003 Jan; 92(1):e12-9. PubMed ID: 12522130
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The cyclin D1-dependent kinase associates with the pre-replication complex and modulates RB.MCM7 binding.
    Gladden AB; Diehl JA
    J Biol Chem; 2003 Mar; 278(11):9754-60. PubMed ID: 12519773
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A dominant-negative cyclin D1 mutant prevents nuclear import of cyclin-dependent kinase 4 (CDK4) and its phosphorylation by CDK-activating kinase.
    Diehl JA; Sherr CJ
    Mol Cell Biol; 1997 Dec; 17(12):7362-74. PubMed ID: 9372967
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Stimulation of the Raf/MEK/ERK cascade is necessary and sufficient for activation and Thr-160 phosphorylation of a nuclear-targeted CDK2.
    Lents NH; Keenan SM; Bellone C; Baldassare JJ
    J Biol Chem; 2002 Dec; 277(49):47469-75. PubMed ID: 12359725
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of ASF/SF2 as a critical, allele-specific effector of the cyclin D1b oncogene.
    Olshavsky NA; Comstock CE; Schiewer MJ; Augello MA; Hyslop T; Sette C; Zhang J; Parysek LM; Knudsen KE
    Cancer Res; 2010 May; 70(10):3975-84. PubMed ID: 20460515
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expression of cyclin D1 splice variants is differentially associated with outcome in non-small cell lung cancer patients.
    Li R; An SJ; Chen ZH; Zhang GC; Zhu JQ; Nie Q; Xie Z; Guo AL; Mok TS; Wu YL
    Hum Pathol; 2008 Dec; 39(12):1792-801. PubMed ID: 18715616
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential requirements for ras and the retinoblastoma tumor suppressor protein in the androgen dependence of prostatic adenocarcinoma cells.
    Fribourg AF; Knudsen KE; Strobeck MW; Lindhorst CM; Knudsen ES
    Cell Growth Differ; 2000 Jul; 11(7):361-72. PubMed ID: 10939590
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2.
    Lan Z; Sever-Chroneos Z; Strobeck MW; Park CH; Baskaran R; Edelmann W; Leone G; Knudsen ES
    J Biol Chem; 2002 Mar; 277(10):8372-81. PubMed ID: 11726663
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cell cycle-independent induction of D1 and D2 cyclin expression, but not cyclin-Cdk complex formation or Rb phosphorylation, by IFNgamma in macrophages.
    Dey A; Li W
    Biochim Biophys Acta; 2000 Jun; 1497(1):135-47. PubMed ID: 10838167
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cell transformation by the E5/E8 protein of bovine papillomavirus type 4. p27(Kip1), Elevated through increased protein synthesis is sequestered by cyclin D1-CDK4 complexes.
    O'Brien V; Grindlay GJ; Campo MS
    J Biol Chem; 2001 Sep; 276(36):33861-8. PubMed ID: 11448948
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1.
    Radu A; Neubauer V; Akagi T; Hanafusa H; Georgescu MM
    Mol Cell Biol; 2003 Sep; 23(17):6139-49. PubMed ID: 12917336
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway.
    Diehl JA; Zindy F; Sherr CJ
    Genes Dev; 1997 Apr; 11(8):957-72. PubMed ID: 9136925
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alternative splicing of the cyclin D1 proto-oncogene is regulated by the RNA-binding protein Sam68.
    Paronetto MP; Cappellari M; Busà R; Pedrotti S; Vitali R; Comstock C; Hyslop T; Knudsen KE; Sette C
    Cancer Res; 2010 Jan; 70(1):229-39. PubMed ID: 20028857
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyclin D1b represses breast cancer cell growth by antagonizing the action of cyclin D1a on estrogen receptor alpha-mediated transcription.
    Zhu J; Sen S; Wei C; Frazier ML
    Int J Oncol; 2010 Jan; 36(1):39-48. PubMed ID: 19956831
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cyclin D1 splice variants: polymorphism, risk, and isoform-specific regulation in prostate cancer.
    Comstock CE; Augello MA; Benito RP; Karch J; Tran TH; Utama FE; Tindall EA; Wang Y; Burd CJ; Groh EM; Hoang HN; Giles GG; Severi G; Hayes VM; Henderson BE; Le Marchand L; Kolonel LN; Haiman CA; Baffa R; Gomella LG; Knudsen ES; Rui H; Henshall SM; Sutherland RL; Knudsen KE
    Clin Cancer Res; 2009 Sep; 15(17):5338-49. PubMed ID: 19706803
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest.
    Srethapakdi M; Liu F; Tavorath R; Rosen N
    Cancer Res; 2000 Jul; 60(14):3940-6. PubMed ID: 10919672
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A cyclin D1/cyclin-dependent kinase 4 binding site within the C domain of the retinoblastoma protein.
    Pan W; Cox S; Hoess RH; Grafström RH
    Cancer Res; 2001 Apr; 61(7):2885-91. PubMed ID: 11306463
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.