BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 12746474)

  • 1. Dysregulation of DNA repair pathways in a transforming growth factor alpha/c-myc transgenic mouse model of accelerated hepatocarcinogenesis.
    Hironaka K; Factor VM; Calvisi DF; Conner EA; Thorgeirsson SS
    Lab Invest; 2003 May; 83(5):643-54. PubMed ID: 12746474
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular analyses of liver tumors in c-myc transgenic mice and c-myc and TGF-alpha double transgenic mice.
    Ohgaki H; Sanderson ND; Ton P; Thorgeirsson SS
    Cancer Lett; 1996 Aug; 106(1):43-9. PubMed ID: 8827045
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Minimal cooperation between mutant Hras and c-myc or TGFα in the regulation of mouse hepatocyte growth or transformation in vivo.
    Stein TJ; Bowden M; Sandgren EP
    Liver Int; 2011 Oct; 31(9):1298-305. PubMed ID: 22093452
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction of c-myc with transforming growth factor alpha and hepatocyte growth factor in hepatocarcinogenesis.
    Thorgeirsson SS; Santoni-Rugiu E
    Mutat Res; 1997 May; 376(1-2):221-34. PubMed ID: 9202759
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interactive effects of c-myc and transforming growth factor alpha transgenes on liver tumor development in simian virus 40 T antigen transgenic mice.
    Enomoto A; Sandgren EP; Maronpot RR
    Vet Pathol; 1998 Jul; 35(4):283-91. PubMed ID: 9684972
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Disruption of redox homeostasis in the transforming growth factor-alpha/c-myc transgenic mouse model of accelerated hepatocarcinogenesis.
    Factor VM; Kiss A; Woitach JT; Wirth PJ; Thorgeirsson SS
    J Biol Chem; 1998 Jun; 273(25):15846-53. PubMed ID: 9624185
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interactions between MYC and transforming growth factor alpha alter the growth and tumorigenicity of liver progenitor cells.
    Cheung RS; Brooling JT; Johnson MM; Riehle KJ; Campbell JS; Fausto N
    Carcinogenesis; 2007 Dec; 28(12):2624-31. PubMed ID: 17698969
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evolution of neoplastic development in the liver of transgenic mice co-expressing c-myc and transforming growth factor-alpha.
    Santoni-Rugiu E; Nagy P; Jensen MR; Factor VM; Thorgeirsson SS
    Am J Pathol; 1996 Aug; 149(2):407-28. PubMed ID: 8701981
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transgenic mouse models in carcinogenesis: interaction of c-myc with transforming growth factor alpha and hepatocyte growth factor in hepatocarcinogenesis.
    Thorgeirsson SS; Santoni-Rugiu E
    Br J Clin Pharmacol; 1996 Jul; 42(1):43-52. PubMed ID: 8807143
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disruption of beta-catenin pathway or genomic instability define two distinct categories of liver cancer in transgenic mice.
    Calvisi DF; Factor VM; Ladu S; Conner EA; Thorgeirsson SS
    Gastroenterology; 2004 May; 126(5):1374-86. PubMed ID: 15131798
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nonrandom cytogenetic alterations in hepatocellular carcinoma from transgenic mice overexpressing c-Myc and transforming growth factor-alpha in the liver.
    Sargent LM; Zhou X; Keck CL; Sanderson ND; Zimonjic DB; Popescu NC; Thorgeirsson SS
    Am J Pathol; 1999 Apr; 154(4):1047-55. PubMed ID: 10233843
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression of base excision DNA repair genes is a sensitive biomarker for in vivo detection of chemical-induced chronic oxidative stress: identification of the molecular source of radicals responsible for DNA damage by peroxisome proliferators.
    Rusyn I; Asakura S; Pachkowski B; Bradford BU; Denissenko MF; Peters JM; Holland SM; Reddy JK; Cunningham ML; Swenberg JA
    Cancer Res; 2004 Feb; 64(3):1050-7. PubMed ID: 14871837
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acceleration of c-myc-induced hepatocarcinogenesis by Co-expression of transforming growth factor (TGF)-alpha in transgenic mice is associated with TGF-beta1 signaling disruption.
    Santoni-Rugiu E; Jensen MR; Factor VM; Thorgeirsson SS
    Am J Pathol; 1999 Jun; 154(6):1693-700. PubMed ID: 10362794
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Disruption of the pRb/E2F pathway and inhibition of apoptosis are major oncogenic events in liver constitutively expressing c-myc and transforming growth factor alpha.
    Santoni-Rugiu E; Jensen MR; Thorgeirsson SS
    Cancer Res; 1998 Jan; 58(1):123-34. PubMed ID: 9426068
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transforming growth factor alpha dramatically enhances oncogene-induced carcinogenesis in transgenic mouse pancreas and liver.
    Sandgren EP; Luetteke NC; Qiu TH; Palmiter RD; Brinster RL; Lee DC
    Mol Cell Biol; 1993 Jan; 13(1):320-30. PubMed ID: 8417334
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Vitamin E down-modulates iNOS and NADPH oxidase in c-Myc/TGF-alpha transgenic mouse model of liver cancer.
    Calvisi DF; Ladu S; Hironaka K; Factor VM; Thorgeirsson SS
    J Hepatol; 2004 Nov; 41(5):815-22. PubMed ID: 15519655
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The peroxisome proliferator WY-14,643 promotes hepatocarcinogenesis caused by endogenously generated oxidative DNA base modifications in repair-deficient Csbm/m/Ogg1-/- mice.
    Trapp C; Schwarz M; Epe B
    Cancer Res; 2007 Jun; 67(11):5156-61. PubMed ID: 17545594
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ploidy and karyotypic alterations associated with early events in the development of hepatocarcinogenesis in transgenic mice harboring c-myc and transforming growth factor alpha transgenes.
    Sargent LM; Sanderson ND; Thorgeirsson SS
    Cancer Res; 1996 May; 56(9):2137-42. PubMed ID: 8616862
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transforming growth factor alpha- and c-myc-induced mammary carcinogenesis in transgenic mice.
    Rose-Hellekant TA; Sandgren EP
    Oncogene; 2000 Feb; 19(8):1092-6. PubMed ID: 10713695
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reduced growth capacity of hepatocytes from c-myc and c-myc/TGF-alpha transgenic mice in primary culture.
    Kao CY; Factor VM; Thorgeirsson SS
    Biochem Biophys Res Commun; 1996 May; 222(1):64-70. PubMed ID: 8630075
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.