BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

150 related articles for article (PubMed ID: 12749895)

  • 21. m-Carborane bisphenol structure as a pharmacophore for selective estrogen receptor modulators.
    Ogawa T; Ohta K; Yoshimi T; Yamazaki H; Suzuki T; Ohta S; Endo Y
    Bioorg Med Chem Lett; 2006 Aug; 16(15):3943-6. PubMed ID: 16735120
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Synthesis and biological evaluation of novel cyclopropyl derivatives as subtype-selective ligands for estrogen receptor.
    Wang Z; Yang Y; Zheng X; Zhang T; Huang W; Yan D; Zhang W; Wang X; Shen Z
    J Pharm Pharmacol; 2018 Jul; 70(7):910-918. PubMed ID: 29582419
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis, antiproliferative and pro-apoptotic activity of 2-phenylindoles.
    Kelly PM; Bright SA; Fayne D; Pollock JK; Zisterer DM; Williams DC; Meegan MJ
    Bioorg Med Chem; 2016 Sep; 24(18):4075-4099. PubMed ID: 27407030
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis and estrogen receptor binding affinities of 7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-ones containing a basic side chain.
    Kim YW; Mobley JA; Brueggemeier RW
    Bioorg Med Chem Lett; 2003 Apr; 13(8):1475-8. PubMed ID: 12668015
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Capitalizing on the complexities of estrogen receptor pharmacology in the quest for the perfect SERM.
    McDonnell DP; Chang CY; Norris JD
    Ann N Y Acad Sci; 2001 Dec; 949():16-35. PubMed ID: 11795348
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Constrained phytoestrogens and analogues as ERbeta selective ligands.
    Miller CP; Collini MD; Harris HA
    Bioorg Med Chem Lett; 2003 Jul; 13(14):2399-403. PubMed ID: 12824043
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Androstene-3,5-dienes as ER-beta selective SERMs.
    Blizzard TA; Gude C; Morgan JD; Chan W; Birzin ET; Mojena M; Tudela C; Chen F; Knecht K; Su Q; Kraker B; Mosley RT; Holmes MA; Rohrer SP; Hammond ML
    Bioorg Med Chem Lett; 2007 Nov; 17(22):6295-8. PubMed ID: 17890084
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Synthesis and preliminary biological evaluation of new carbon-11 labeled tetrahydroisoquinoline derivatives as SERM radioligands for PET imaging of ER expression in breast cancer.
    Gao M; Wang M; Miller KD; Sledge GW; Zheng QH
    Eur J Med Chem; 2008 Oct; 43(10):2211-9. PubMed ID: 18272256
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Rapid synthesis of 4-benzylidene and 4-[bis-(4-methoxyphenyl)-methylene-2-substituted phenyl-benzopyrans as potential selective estrogen receptor modulators (SERMs) using McMurry coupling reaction.
    Gupta A; Dwivedy A; Keshri G; Sharma R; Balapure AK; Singh MM; Ray S
    Bioorg Med Chem Lett; 2006 Dec; 16(23):6006-12. PubMed ID: 16979337
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Protein structure-based design, synthesis strategy and in vitro pharmacological characterization of estrogen receptor alpha and beta selective compounds.
    Hillisch A; Peters O; Kosemund D; Müller G; Walter A; Elger W; Fritzemeier KH
    Ernst Schering Res Found Workshop; 2004; (46):47-62. PubMed ID: 15248504
    [No Abstract]   [Full Text] [Related]  

  • 31. Estrogen receptor ligands. Part 7: Dihydrobenzoxathiin SERAMs with bicyclic amine side chains.
    Blizzard TA; DiNinno F; Morgan JD; Chen HY; Wu JY; Gude C; Kim S; Chan W; Birzin ET; Tien Yang Y; Pai LY; Zhang Z; Hayes EC; DaSilva CA; Tang W; Rohrer SP; Schaeffer JM; Hammond ML
    Bioorg Med Chem Lett; 2004 Aug; 14(15):3861-4. PubMed ID: 15225685
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Selective estrogen receptor modulator medicinal chemistry at Merck. A review.
    Blizzard TA
    Curr Top Med Chem; 2008; 8(9):792-812. PubMed ID: 18537689
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Estrogen receptor ligands. Part 8: Dihydrobenzoxathiin SERAMs with heteroatom-substituted side chains.
    Blizzard TA; DiNinno F; Morgan JD; Wu JY; Chen HY; Kim S; Chan W; Birzin ET; Yang YT; Pai LY; Zhang Z; Hayes EC; DaSilva CA; Tang W; Rohrer SP; Schaeffer JM; Hammond ML
    Bioorg Med Chem Lett; 2004 Aug; 14(15):3865-8. PubMed ID: 15225686
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Antagonists selective for estrogen receptor alpha.
    Sun J; Huang YR; Harrington WR; Sheng S; Katzenellenbogen JA; Katzenellenbogen BS
    Endocrinology; 2002 Mar; 143(3):941-7. PubMed ID: 11861516
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Aerobic iron-based cross-dehydrogenative coupling enables efficient diversity-oriented synthesis of coumestrol-based selective estrogen receptor modulators.
    Kshirsagar UA; Parnes R; Goldshtein H; Ofir R; Zarivach R; Pappo D
    Chemistry; 2013 Sep; 19(40):13575-83. PubMed ID: 23946113
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Detection of Endogenous Selective Estrogen Receptor Modulators such as 27-Hydroxycholesterol.
    Nelson ER
    Methods Mol Biol; 2016; 1366():431-443. PubMed ID: 26585155
    [TBL] [Abstract][Full Text] [Related]  

  • 37. 27-hydroxycholesterol is an endogenous selective estrogen receptor modulator.
    DuSell CD; Umetani M; Shaul PW; Mangelsdorf DJ; McDonnell DP
    Mol Endocrinol; 2008 Jan; 22(1):65-77. PubMed ID: 17872378
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Estrogen receptor ligands. Part 4: The SAR of the syn-dihydrobenzoxathiin SERAMs.
    Kim S; Wu J; Chen HY; Birzin ET; Chan W; Yang YT; Colwell L; Li S; Dahllund J; DiNinno F; Rohrer SP; Schaeffer JM; Hammond ML
    Bioorg Med Chem Lett; 2004 Jun; 14(11):2741-5. PubMed ID: 15125925
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Capacity of type I and II ligands to confer to estrogen receptor alpha an appropriate conformation for the recruitment of coactivators containing a LxxLL motif-Relationship with the regulation of receptor level and ERE-dependent transcription in MCF-7 cells.
    Bourgoin-Voillard S; Gallo D; Laïos I; Cleeren A; Bali LE; Jacquot Y; Nonclercq D; Laurent G; Tabet JC; Leclercq G
    Biochem Pharmacol; 2010 Mar; 79(5):746-57. PubMed ID: 19879249
    [TBL] [Abstract][Full Text] [Related]  

  • 40. New scaffolds for the design of selective estrogen receptor modulators.
    Martín-Santamaría S; Rodríguez JJ; de Pascual-Teresa S; Gordon S; Bengtsson M; Garrido-Laguna I; Rubio-Viqueira B; López-Casas PP; Hidalgo M; de Pascual-Teresa B; Ramos A
    Org Biomol Chem; 2008 Oct; 6(19):3486-96. PubMed ID: 19082149
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.