BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

84 related articles for article (PubMed ID: 12750430)

  • 1. Rat hepatic CYP2E1 is induced by very low nicotine doses: an investigation of induction, time course, dose response, and mechanism.
    Micu AL; Miksys S; Sellers EM; Koop DR; Tyndale RF
    J Pharmacol Exp Ther; 2003 Sep; 306(3):941-7. PubMed ID: 12750430
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Low doses of nicotine and ethanol induce CYP2E1 and chlorzoxazone metabolism in rat liver.
    Howard LA; Micu AL; Sellers EM; Tyndale RF
    J Pharmacol Exp Ther; 2001 Nov; 299(2):542-50. PubMed ID: 11602665
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction and recovery time course of rat brain CYP2E1 after nicotine treatment.
    Joshi M; Tyndale RF
    Drug Metab Dispos; 2006 Apr; 34(4):647-52. PubMed ID: 16434548
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vivo and in vitro characterization of chlorzoxazone metabolism and hepatic CYP2E1 levels in African Green monkeys: induction by chronic nicotine treatment.
    Lee AM; Yue J; Tyndale RF
    Drug Metab Dispos; 2006 Sep; 34(9):1508-15. PubMed ID: 16763012
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake.
    Yue J; Khokhar J; Miksys S; Tyndale RF
    Eur J Pharmacol; 2009 May; 609(1-3):88-95. PubMed ID: 19285975
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regional and cellular induction of nicotine-metabolizing CYP2B1 in rat brain by chronic nicotine treatment.
    Miksys S; Hoffmann E; Tyndale RF
    Biochem Pharmacol; 2000 Jun; 59(12):1501-11. PubMed ID: 10799646
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dose-dependent up-regulation of rat pulmonary, renal, and hepatic cytochrome P-450 (CYP) 1A expression by nicotine feeding.
    Iba MM; Fung J; Pak YW; Thomas PE; Fisher H; Sekowski A; Halladay AK; Wagner GC
    Drug Metab Dispos; 1999 Sep; 27(9):977-82. PubMed ID: 10460794
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics.
    Howard LA; Miksys S; Hoffmann E; Mash D; Tyndale RF
    Br J Pharmacol; 2003 Apr; 138(7):1376-86. PubMed ID: 12711639
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of human cytochrome P450 2E1 by nicotine, cotinine, and aqueous cigarette tar extract in vitro.
    Van Vleet TR; Bombick DW; Coulombe RA
    Toxicol Sci; 2001 Dec; 64(2):185-91. PubMed ID: 11719700
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regional and cellular distribution of CYP2E1 in monkey brain and its induction by chronic nicotine.
    Joshi M; Tyndale RF
    Neuropharmacology; 2006 Apr; 50(5):568-75. PubMed ID: 16368115
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of nicotine-metabolizing CYP2B1 by ethanol and ethanol-metabolizing CYP2E1 by nicotine: summary and implications.
    Schoedel KA; Tyndale RF
    Biochim Biophys Acta; 2003 Feb; 1619(3):283-90. PubMed ID: 12573488
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nicotine induces brain CYP enzymes: relevance to Parkinson's disease.
    Miksys S; Tyndale RF
    J Neural Transm Suppl; 2006; (70):177-80. PubMed ID: 17017527
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rat brain CYP2B induction by nicotine is persistent and does not involve nicotinic acetylcholine receptors.
    Khokhar JY; Miksys SL; Tyndale RF
    Brain Res; 2010 Aug; 1348():1-9. PubMed ID: 20599831
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chronic nicotine treatment induces rat CYP2D in the brain but not in the liver: an investigation of induction and time course.
    Yue J; Miksys S; Hoffmann E; Tyndale RF
    J Psychiatry Neurosci; 2008 Jan; 33(1):54-63. PubMed ID: 18197273
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cigarette smoke, nicotine and cotinine protect against 6-hydroxydopamine-induced toxicity in SH-SY5Y cells.
    Riveles K; Huang LZ; Quik M
    Neurotoxicology; 2008 May; 29(3):421-7. PubMed ID: 18359086
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of hydrazine, phenelzine, and hydralazine treatment on rat hepatic and renal drug-metabolizing enzyme expression.
    Runge-Morris M; Feng Y; Zangar RC; Novak RF
    Drug Metab Dispos; 1996 Jul; 24(7):734-7. PubMed ID: 8818569
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Xenobiotic-enhanced expression of cytochromes P450 2E1 and 2B in primary cultured rat hepatocytes.
    Woodcroft KJ; Novak RF
    Drug Metab Dispos; 1998 Apr; 26(4):372-8. PubMed ID: 9531527
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tobacco smoke-dependent changes in cytochrome P450 1A1, 1A2, and 2E1 protein expressions in fetuses, newborns, pregnant rats, and human placenta.
    Czekaj P; Wiaderkiewicz A; Florek E; Wiaderkiewicz R
    Arch Toxicol; 2005 Jan; 79(1):13-24. PubMed ID: 15448981
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of nicotine on cytochrome P450 2A6 and 2E1 activities.
    Hukkanen J; Jacob Iii P; Peng M; Dempsey D; Benowitz NL
    Br J Clin Pharmacol; 2010 Feb; 69(2):152-9. PubMed ID: 20233178
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lack of cytochrome P450 2E1 (CYP2E1) induction in the rat liver by starvation without coprophagy.
    Chung HC; Sung SH; Kim JS; Kim YC; Kim SG
    Drug Metab Dispos; 2001 Mar; 29(3):213-6. PubMed ID: 11181486
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.