BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

121 related articles for article (PubMed ID: 12754290)

  • 1. Skeletal muscles express the xenobiotic-metabolizing enzyme arylamine N-acetyltransferase.
    Rodrigues-Lima F; Cooper RN; Goudeau B; Atmane N; Chamagne AM; Butler-Browne G; Sim E; Vicart P; Dupret JM
    J Histochem Cytochem; 2003 Jun; 51(6):789-96. PubMed ID: 12754290
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Placental expression of arylamine N-acetyltransferases: evidence for linkage disequilibrium between NAT1*10 and NAT2*4 alleles of the two human arylamine N-acetyltransferase loci NAT1 and NAT2.
    Smelt VA; Mardon HJ; Sim E
    Pharmacol Toxicol; 1998 Oct; 83(4):149-57. PubMed ID: 9820875
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Isoform-selective inactivation of human arylamine N-acetyltransferases by reactive metabolites of carcinogenic arylamines.
    Liu L; Wagner CR; Hanna PE
    Chem Res Toxicol; 2009 Dec; 22(12):1962-74. PubMed ID: 19842618
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impairment of the activity of the xenobiotic-metabolizing enzymes arylamine N-acetyltransferases 1 and 2 (NAT1/NAT2) by peroxynitrite in mouse skeletal muscle cells.
    Dairou J; Dupret JM; Rodrigues-Lima F
    FEBS Lett; 2005 Aug; 579(21):4719-23. PubMed ID: 16098511
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The xenobiotic-metabolizing enzymes arylamine N-acetyltransferases in human lens epithelial cells: inactivation by cellular oxidants and UVB-induced oxidative stress.
    Dairou J; Malecaze F; Dupret JM; Rodrigues-Lima F
    Mol Pharmacol; 2005 Apr; 67(4):1299-306. PubMed ID: 15644493
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding.
    Laurieri N; Kawamura A; Westwood IM; Varney A; Morris E; Russell AJ; Stanley LA; Sim E
    BMC Pharmacol Toxicol; 2014 Nov; 15():68. PubMed ID: 25432241
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure and regulation of the drug-metabolizing enzymes arylamine N-acetyltransferases.
    Dupret JM; Rodrigues-Lima F
    Curr Med Chem; 2005; 12(3):311-8. PubMed ID: 15723621
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Arylamine N-acetyltransferases: characterization of the substrate specificities and molecular interactions of environmental arylamines with human NAT1 and NAT2.
    Liu L; Von Vett A; Zhang N; Walters KJ; Wagner CR; Hanna PE
    Chem Res Toxicol; 2007 Sep; 20(9):1300-8. PubMed ID: 17672512
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Bacillus anthracis arylamine N-acetyltransferase ((BACAN)NAT1) that inactivates sulfamethoxazole, reveals unusual structural features compared with the other NAT isoenzymes.
    Pluvinage B; Li de la Sierra-Gallay I; Kubiak X; Xu X; Dairou J; Dupret JM; Rodrigues-Lima F
    FEBS Lett; 2011 Dec; 585(24):3947-52. PubMed ID: 22062153
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression of arylamine N-acetyltransferase in human intestine.
    Hickman D; Pope J; Patil SD; Fakis G; Smelt V; Stanley LA; Payton M; Unadkat JD; Sim E
    Gut; 1998 Mar; 42(3):402-9. PubMed ID: 9577349
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes.
    Grant DM; Blum M; Beer M; Meyer UA
    Mol Pharmacol; 1991 Feb; 39(2):184-91. PubMed ID: 1996083
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of the xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 as a new target of cisplatin in breast cancer cells: molecular and cellular mechanisms of inhibition.
    Ragunathan N; Dairou J; Pluvinage B; Martins M; Petit E; Janel N; Dupret JM; Rodrigues-Lima F
    Mol Pharmacol; 2008 Jun; 73(6):1761-8. PubMed ID: 18310302
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Arylamine N-acetyltransferases: structural and functional implications of polymorphisms.
    Sim E; Lack N; Wang CJ; Long H; Westwood I; Fullam E; Kawamura A
    Toxicology; 2008 Dec; 254(3):170-83. PubMed ID: 18852012
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism.
    Wakefield L; Cornish V; Long H; Griffiths WJ; Sim E
    Biochem Biophys Res Commun; 2007 Dec; 364(3):556-60. PubMed ID: 17961509
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Neonatal ontogeny of murine arylamine N-acetyltransferases: implications for arylamine genotoxicity.
    McQueen CA; Chau B
    Toxicol Sci; 2003 Jun; 73(2):279-86. PubMed ID: 12700401
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice.
    Sugamori KS; Wong S; Gaedigk A; Yu V; Abramovici H; Rozmahel R; Grant DM
    Mol Pharmacol; 2003 Jul; 64(1):170-9. PubMed ID: 12815173
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Longitudinal distribution of arylamine N-acetyltransferases in the intestine of the hamster, mouse, and rat. Evidence for multiplicity of N-acetyltransferases in the intestine.
    Ware JA; Svensson CK
    Biochem Pharmacol; 1996 Nov; 52(10):1613-20. PubMed ID: 8937477
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human arylamine N-acetyltransferase 1: in vitro and intracellular inactivation by nitrosoarene metabolites of toxic and carcinogenic arylamines.
    Liu L; Wagner CR; Hanna PE
    Chem Res Toxicol; 2008 Oct; 21(10):2005-16. PubMed ID: 18759501
    [TBL] [Abstract][Full Text] [Related]  

  • 19. N-Acetyltransferase and sulfotransferase activity in human prostate: potential for carcinogen activation.
    Al-Buheissi SZ; Patel HR; Meinl W; Hewer A; Bryan RL; Glatt H; Miller RA; Phillips DH
    Pharmacogenet Genomics; 2006 Jun; 16(6):391-9. PubMed ID: 16708048
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cloning, sequencing, and recombinant expression of NAT1, NAT2, and NAT3 derived from the C3H/HeJ (rapid) and A/HeJ (slow) acetylator inbred mouse: functional characterization of the activation and deactivation of aromatic amine carcinogens.
    Fretland AJ; Doll MA; Gray K; Feng Y; Hein DW
    Toxicol Appl Pharmacol; 1997 Feb; 142(2):360-6. PubMed ID: 9070359
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.