These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

67 related articles for article (PubMed ID: 12754302)

  • 1. The role of phosphatidylinositol 3'-kinase and its downstream signals in erbB-2-mediated transformation.
    Woods Ignatoski KM; Livant DL; Markwart S; Grewal NK; Ethier SP
    Mol Cancer Res; 2003 May; 1(7):551-60. PubMed ID: 12754302
    [TBL] [Abstract][Full Text] [Related]  

  • 2. p38MAPK induces cell surface alpha4 integrin downregulation to facilitate erbB-2-mediated invasion.
    Woods Ignatoski KM; Grewal NK; Markwart S; Livant DL; Ethier SP
    Neoplasia; 2003; 5(2):128-34. PubMed ID: 12659685
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ErbB2-overexpressing human mammary carcinoma cells display an increased requirement for the phosphatidylinositol 3-kinase signaling pathway in anchorage-independent growth.
    Hermanto U; Zong CS; Wang LH
    Oncogene; 2001 Nov; 20(51):7551-62. PubMed ID: 11709727
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive phosphatidylinositol 3'-kinase/Akt pathway signaling.
    She QB; Solit D; Basso A; Moasser MM
    Clin Cancer Res; 2003 Oct; 9(12):4340-6. PubMed ID: 14555504
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphatidylinositol 3-kinase recruitment by p185erbB-2 and erbB-3 is potently induced by neu differentiation factor/heregulin during mitogenesis and is constitutively elevated in growth factor-independent breast carcinoma cells with c-erbB-2 gene amplification.
    Ram TG; Ethier SP
    Cell Growth Differ; 1996 May; 7(5):551-61. PubMed ID: 8732665
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential activation of the phosphatidylinositol 3'-kinase/Akt survival pathway by ionizing radiation in tumor and primary endothelial cells.
    Zingg D; Riesterer O; Fabbro D; Glanzmann C; Bodis S; Pruschy M
    Cancer Res; 2004 Aug; 64(15):5398-406. PubMed ID: 15289348
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p38MAPK-activated AKT in HER-2 overexpressing human breast cancer cells acts as an EGF-independent survival signal.
    Diehl KM; Grewal N; Ethier SP; Woods-Ignatoski KM
    J Surg Res; 2007 Sep; 142(1):162-9. PubMed ID: 17612563
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of estradiol on estrogen receptor-alpha gene expression and activity can be modulated by the ErbB2/PI 3-K/Akt pathway.
    Stoica GE; Franke TF; Moroni M; Mueller S; Morgan E; Iann MC; Winder AD; Reiter R; Wellstein A; Martin MB; Stoica A
    Oncogene; 2003 Sep; 22(39):7998-8011. PubMed ID: 12970748
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of a conditionally active v-ErbB and an EGF-R inhibitor on transformation of NIH-3T3 cells and abrogation of cytokine dependency of hematopoietic cells.
    McCubrey JA; Shelton JG; Steelman LS; Franklin RA; Sreevalsan T; McMahon M
    Oncogene; 2004 Oct; 23(47):7810-20. PubMed ID: 15361836
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Epidermal growth factor modulates prostate cancer cell invasiveness regulating urokinase-type plasminogen activator activity. EGF-receptor inhibition may prevent tumor cell dissemination.
    Festuccia C; Angelucci A; Gravina GL; Biordi L; Millimaggi D; Muzi P; Vicentini C; Bologna M
    Thromb Haemost; 2005 May; 93(5):964-75. PubMed ID: 15886816
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia.
    Blalock WL; Navolanic PM; Steelman LS; Shelton JG; Moye PW; Lee JT; Franklin RA; Mirza A; McMahon M; White MK; McCubrey JA
    Leukemia; 2003 Jun; 17(6):1058-67. PubMed ID: 12764369
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells.
    Badache A; Hynes NE
    Cancer Res; 2001 Jan; 61(1):383-91. PubMed ID: 11196191
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.
    McCubrey JA; Steelman LS; Abrams SL; Lee JT; Chang F; Bertrand FE; Navolanic PM; Terrian DM; Franklin RA; D'Assoro AB; Salisbury JL; Mazzarino MC; Stivala F; Libra M
    Adv Enzyme Regul; 2006; 46():249-79. PubMed ID: 16854453
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphoinositide-3 kinase-PKB/Akt pathway activation is involved in fibroblast Rat-1 transformation by human T-cell leukemia virus type I tax.
    Liu Y; Wang Y; Yamakuchi M; Masuda S; Tokioka T; Yamaoka S; Maruyama I; Kitajima I
    Oncogene; 2001 May; 20(20):2514-26. PubMed ID: 11420661
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.
    Zhong H; Chiles K; Feldser D; Laughner E; Hanrahan C; Georgescu MM; Simons JW; Semenza GL
    Cancer Res; 2000 Mar; 60(6):1541-5. PubMed ID: 10749120
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.
    Lenferink AE; Busse D; Flanagan WM; Yakes FM; Arteaga CL
    Cancer Res; 2001 Sep; 61(17):6583-91. PubMed ID: 11522658
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ERBB-2 overexpression confers PI 3' kinase-dependent invasion capacity on human mammary epithelial cells.
    Ignatoski KM; Maehama T; Markwart SM; Dixon JE; Livant DL; Ethier SP
    Br J Cancer; 2000 Feb; 82(3):666-74. PubMed ID: 10682681
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of phosphatidylinositol 3-kinase-Akt pathway in nucleophosmin/anaplastic lymphoma kinase-mediated lymphomagenesis.
    Slupianek A; Nieborowska-Skorska M; Hoser G; Morrione A; Majewski M; Xue L; Morris SW; Wasik MA; Skorski T
    Cancer Res; 2001 Mar; 61(5):2194-9. PubMed ID: 11280786
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of PI3K-Akt signaling pathway promotes prostate cancer cell invasion.
    Shukla S; Maclennan GT; Hartman DJ; Fu P; Resnick MI; Gupta S
    Int J Cancer; 2007 Oct; 121(7):1424-32. PubMed ID: 17551921
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Neuregulins rescue PC12-ErbB-4 cells from cell death induced by beta-amyloid peptide: involvement of PI3K and PKC.
    Di Segni A; Shaharabani E; Stein R; Pinkas-Kramarski R
    J Mol Neurosci; 2005; 26(1):57-69. PubMed ID: 15968086
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.