BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

320 related articles for article (PubMed ID: 12755607)

  • 21. Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: important implications for the mechanism of catalysis.
    Bzowska A; Koellner G; Wielgus-Kutrowska B; Stroh A; Raszewski G; Holý A; Steiner T; Frank J
    J Mol Biol; 2004 Sep; 342(3):1015-32. PubMed ID: 15342253
    [TBL] [Abstract][Full Text] [Related]  

  • 22. [Tight binding transition state analogues of purine nucleoside phosphorylase--meaning, design and properties].
    Lewandowicz A
    Postepy Biochem; 2004; 50(3):218-27. PubMed ID: 15822751
    [No Abstract]   [Full Text] [Related]  

  • 23. Energetic mapping of transition state analogue interactions with human and Plasmodium falciparum purine nucleoside phosphorylases.
    Lewandowicz A; Ringia EA; Ting LM; Kim K; Tyler PC; Evans GB; Zubkova OV; Mee S; Painter GF; Lenz DH; Furneaux RH; Schramm VL
    J Biol Chem; 2005 Aug; 280(34):30320-8. PubMed ID: 15961383
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase.
    Lewandowicz A; Tyler PC; Evans GB; Furneaux RH; Schramm VL
    J Biol Chem; 2003 Aug; 278(34):31465-8. PubMed ID: 12842889
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis of a transition state analogue inhibitor of purine nucleoside phosphorylase via the Mannich reaction.
    Evans GB; Furneaux RH; Tyler PC; Schramm VL
    Org Lett; 2003 Oct; 5(20):3639-40. PubMed ID: 14507192
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function.
    Shi W; Ting LM; Kicska GA; Lewandowicz A; Tyler PC; Evans GB; Furneaux RH; Kim K; Almo SC; Schramm VL
    J Biol Chem; 2004 Apr; 279(18):18103-6. PubMed ID: 14982926
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Intracellular rebinding of transition-state analogues provides extended
    Gebre ST; Cameron SA; Li L; Babu YS; Schramm VL
    J Biol Chem; 2017 Sep; 292(38):15907-15915. PubMed ID: 28794158
    [TBL] [Abstract][Full Text] [Related]  

  • 28. 1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state.
    Chojnowski G; Breer K; Narczyk M; Wielgus-Kutrowska B; Czapinska H; Hashimoto M; Hikishima S; Yokomatsu T; Bochtler M; Girstun A; Staroń K; Bzowska A
    Biochem Biophys Res Commun; 2010 Jan; 391(1):703-8. PubMed ID: 19944078
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase.
    Evans GB; Furneaux RH; Schramm VL; Singh V; Tyler PC
    J Med Chem; 2004 Jun; 47(12):3275-81. PubMed ID: 15163207
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Purine nucleoside phosphorylase from Mycobacterium tuberculosis. Analysis of inhibition by a transition-state analogue and dissection by parts.
    Basso LA; Santos DS; Shi W; Furneaux RH; Tyler PC; Schramm VL; Blanchard JS
    Biochemistry; 2001 Jul; 40(28):8196-203. PubMed ID: 11444965
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Distortional binding of transition state analogs to human purine nucleoside phosphorylase probed by magic angle spinning solid-state NMR.
    Vetticatt MJ; Itin B; Evans GB; Schramm VL
    Proc Natl Acad Sci U S A; 2013 Oct; 110(40):15991-6. PubMed ID: 24043827
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor.
    Shi W; Li CM; Tyler PC; Furneaux RH; Cahill SM; Girvin ME; Grubmeyer C; Schramm VL; Almo SC
    Biochemistry; 1999 Aug; 38(31):9872-80. PubMed ID: 10433693
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Calf spleen purine-nucleoside phosphorylase: crystal structure of the binary complex with a potent multisubstrate analogue inhibitor.
    Luić M; Koellner G; Yokomatsu T; Shibuya S; Bzowska A
    Acta Crystallogr D Biol Crystallogr; 2004 Aug; 60(Pt 8):1417-24. PubMed ID: 15272165
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Crystal structure and molecular dynamics studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis associated with acyclovir.
    Caceres RA; Timmers LF; Ducati RG; da Silva DO; Basso LA; de Azevedo WF; Santos DS
    Biochimie; 2012 Jan; 94(1):155-65. PubMed ID: 22033138
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Transition state analogues for enzymes of nucleic acid metabolism.
    Schramm VL
    Nucleic Acids Res Suppl; 2003; (3):107-8. PubMed ID: 14510403
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis.
    Versées W; Barlow J; Steyaert J
    J Mol Biol; 2006 Jun; 359(2):331-46. PubMed ID: 16630632
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structure of human PNP complexed with ligands.
    Canduri F; Silva RG; dos Santos DM; Palma MS; Basso LA; Santos DS; de Azevedo WF
    Acta Crystallogr D Biol Crystallogr; 2005 Jul; 61(Pt 7):856-62. PubMed ID: 15983407
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Crystallographic structure of PNP from Mycobacterium tuberculosis at 1.9A resolution.
    Nolasco DO; Canduri F; Pereira JH; Cortinóz JR; Palma MS; Oliveira JS; Basso LA; de Azevedo WF; Santos DS
    Biochem Biophys Res Commun; 2004 Nov; 324(2):789-94. PubMed ID: 15474496
    [TBL] [Abstract][Full Text] [Related]  

  • 39. New catalytic mechanism for human purine nucleoside phosphorylase.
    Canduri F; Fadel V; Basso LA; Palma MS; Santos DS; de Azevedo WF
    Biochem Biophys Res Commun; 2005 Feb; 327(3):646-9. PubMed ID: 15649395
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Transition states and inhibitors of the purine nucleoside phosphorylase family.
    Taylor Ringia EA; Schramm VL
    Curr Top Med Chem; 2005; 5(13):1237-58. PubMed ID: 16305529
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.