BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1110 related articles for article (PubMed ID: 12755637)

  • 1. DNA binding mode of the cis and trans geometries of new antitumor nonclassical platinum complexes containing piperidine, piperazine, or 4-picoline ligand in cell-free media. Relations to their activity in cancer cell lines.
    Kasparkova J; Marini V; Najajreh Y; Gibson D; Brabec V
    Biochemistry; 2003 May; 42(20):6321-32. PubMed ID: 12755637
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA interactions of new antitumor platinum complexes with trans geometry activated by a 2-metylbutylamine or sec-butylamine ligand.
    Prokop R; Kasparkova J; Novakova O; Marini V; Pizarro AM; Navarro-Ranninger C; Brabec V
    Biochem Pharmacol; 2004 Mar; 67(6):1097-109. PubMed ID: 15006546
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA binding by antitumor trans-[PtCl2(NH3)(thiazole)]. Protein recognition and nucleotide excision repair of monofunctional adducts.
    Kasparkova J; Novakova O; Farrell N; Brabec V
    Biochemistry; 2003 Jan; 42(3):792-800. PubMed ID: 12534292
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of a piperidine ligand on DNA modification by antitumor cisplatin analogues.
    Kasparkova J; Novakova O; Najajreh Y; Gibson D; Perez JM; Brabec V
    Chem Res Toxicol; 2003 Nov; 16(11):1424-32. PubMed ID: 14615968
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA interactions of new cytotoxic tetrafunctional dinuclear platinum complex trans,trans-[{PtCl2(NH3)}2(piperazine)].
    Brabec V; Christofis P; Slámová M; Kostrhunová H; Nováková O; Najajreh Y; Gibson D; Kaspárková J
    Biochem Pharmacol; 2007 Jun; 73(12):1887-900. PubMed ID: 17400194
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Unique properties of DNA interstrand cross-links of antitumor oxaliplatin and the effect of chirality of the carrier ligand.
    Kasparkova J; Vojtiskova M; Natile G; Brabec V
    Chemistry; 2008; 14(4):1330-41. PubMed ID: 18022972
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanism-related circumvention of acquired cis-diamminedichloroplatinum(II) resistance using two pairs of human ovarian carcinoma cell lines by ammine/amine platinum(IV) dicarboxylates.
    Kelland LR; Mistry P; Abel G; Loh SY; O'Neill CF; Murrer BA; Harrap KR
    Cancer Res; 1992 Jul; 52(14):3857-64. PubMed ID: 1617660
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biochemical pharmacology of homologous alicyclic mixed amine platinum(II) complexes in sensitive and resistant tumor cell lines.
    Yoshida M; Khokhar AR; Siddik ZH
    Cancer Res; 1994 Jul; 54(13):3468-73. PubMed ID: 8012968
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism of cytotoxicity of anticancer platinum drugs: evidence that cis-diamminedichloroplatinum(II) and cis-diammine-(1,1-cyclobutanedicarboxylato)platinum(II) differ only in the kinetics of their interaction with DNA.
    Knox RJ; Friedlos F; Lydall DA; Roberts JJ
    Cancer Res; 1986 Apr; 46(4 Pt 2):1972-9. PubMed ID: 3512077
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of trans geometry in bifunctional mononuclear platinum complexes by a non-bulky methylamine ligand.
    Frybortova M; Novakova O; Stepankova J; Novohradsky V; Gibson D; Kasparkova J; Brabec V
    J Inorg Biochem; 2013 Sep; 126():46-54. PubMed ID: 23770803
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of geometric isomerism in dinuclear platinum antitumor complexes on DNA interstrand cross-linking.
    Kaspárková J; Nováková O; Vrána O; Farrell N; Brabec V
    Biochemistry; 1999 Aug; 38(34):10997-1005. PubMed ID: 10460154
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural characterization and DNA interactions of new cytotoxic transplatin analogues containing one planar and one nonplanar heterocyclic amine ligand.
    Najajreh Y; Kasparkova J; Marini V; Gibson D; Brabec V
    J Biol Inorg Chem; 2005 Nov; 10(7):722-31. PubMed ID: 16208494
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chemical, biochemical and pharmacological activity of the novel sterically hindered platinum co-ordination complex, cis-[amminedichloro(2-methylpyridine)] platinum(II) (AMD473).
    Holford J; Raynaud F; Murrer BA; Grimaldi K; Hartley JA; Abrams M; Kelland LR
    Anticancer Drug Des; 1998 Jan; 13(1):1-18. PubMed ID: 9474239
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of the geometry of the central coordination sphere in antitumor trinuclear platinum complexes on DNA binding.
    Kasparkova J; Vrana O; Farrell N; Brabec V
    J Inorg Biochem; 2004 Oct; 98(10):1560-9. PubMed ID: 15458817
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro.
    Kostrhunova H; Vrana O; Suchankova T; Gibson D; Kasparkova J; Brabec V
    Chem Res Toxicol; 2010 Nov; 23(11):1833-42. PubMed ID: 20939593
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biophysical analysis of natural, double-helical DNA modified by a dinuclear platinum(II) organometallic compound in a cell-free medium.
    Marini V; Kasparkova J; Novakova O; Monsú Scolaro L; Romeo R; Brabec V
    J Biol Inorg Chem; 2002 Sep; 7(7-8):725-34. PubMed ID: 12203009
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural characterization, DNA interactions, and cytotoxicity of new transplatin analogues containing one aliphatic and one planar heterocyclic amine ligand.
    Ramos-Lima FJ; Vrána O; Quiroga AG; Navarro-Ranninger C; Halámiková A; Rybnícková H; Hejmalová L; Brabec V
    J Med Chem; 2006 Apr; 49(8):2640-51. PubMed ID: 16610807
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cytotoxicity, mutagenicity, cellular uptake, DNA and glutathione interactions of lipophilic trans-platinum complexes tethered to 1-adamantylamine.
    Halámiková A; Heringová P; Kaspárková J; Intini FP; Natile G; Nemirovski A; Gibson D; Brabec V
    J Inorg Biochem; 2008; 102(5-6):1077-89. PubMed ID: 18237783
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modulation of cytotoxicity and cellular pharmacology of 1,2-diaminocyclohexane platinum (IV) complexes mediated by axial and equatorial ligands.
    Kido Y; Khokhar AR; al-Baker S; Siddik ZH
    Cancer Res; 1993 Oct; 53(19):4567-72. PubMed ID: 8402629
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA interactions of a novel platinum drug, cis-[PtCl(NH3)2(N7-acyclovir)]+.
    Balcarová Z; Kaspárková J; Zákovská A; Nováková O; Sivo MF; Natile G; Brabec V
    Mol Pharmacol; 1998 May; 53(5):846-55. PubMed ID: 9584210
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 56.