BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 12759351)

  • 1. Phosphorylation at serine 75 is required for UV-mediated degradation of human Cdc25A phosphatase at the S-phase checkpoint.
    Hassepass I; Voit R; Hoffmann I
    J Biol Chem; 2003 Aug; 278(32):29824-9. PubMed ID: 12759351
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase.
    Jin J; Shirogane T; Xu L; Nalepa G; Qin J; Elledge SJ; Harper JW
    Genes Dev; 2003 Dec; 17(24):3062-74. PubMed ID: 14681206
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase.
    Jin J; Ang XL; Ye X; Livingstone M; Harper JW
    J Biol Chem; 2008 Jul; 283(28):19322-8. PubMed ID: 18480045
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Degradation of Cdc25A phosphatase in HeLa cells under normal and stress conditions].
    Goloudina AR; Aksenov ND; Pospelov VA
    Tsitologiia; 2004; 46(5):423-30. PubMed ID: 15344887
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rapid destruction of human Cdc25A in response to DNA damage.
    Mailand N; Falck J; Lukas C; Syljuâsen RG; Welcker M; Bartek J; Lukas J
    Science; 2000 May; 288(5470):1425-9. PubMed ID: 10827953
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential impact of diverse anticancer chemotherapeutics on the Cdc25A-degradation checkpoint pathway.
    Agner J; Falck J; Lukas J; Bartek J
    Exp Cell Res; 2005 Jan; 302(2):162-9. PubMed ID: 15561098
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents.
    Xiao Z; Chen Z; Gunasekera AH; Sowin TJ; Rosenberg SH; Fesik S; Zhang H
    J Biol Chem; 2003 Jun; 278(24):21767-73. PubMed ID: 12676925
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis.
    Falck J; Mailand N; Syljuåsen RG; Bartek J; Lukas J
    Nature; 2001 Apr; 410(6830):842-7. PubMed ID: 11298456
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of cyclin-dependent kinase 2 by the Chk1-Cdc25A pathway during the S-phase checkpoint activated by fludarabine: dysregulation by 7-hydroxystaurosporine.
    Sampath D; Shi Z; Plunkett W
    Mol Pharmacol; 2002 Sep; 62(3):680-8. PubMed ID: 12181445
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of human Cdc25A stability by Serine 75 phosphorylation is not sufficient to activate a S phase checkpoint.
    Goloudina A; Yamaguchi H; Chervyakova DB; Appella E; Fornace AJ; Bulavin DV
    Cell Cycle; 2003; 2(5):473-8. PubMed ID: 12963847
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.
    Sørensen CS; Syljuåsen RG; Falck J; Schroeder T; Rönnstrand L; Khanna KK; Zhou BB; Bartek J; Lukas J
    Cancer Cell; 2003 Mar; 3(3):247-58. PubMed ID: 12676583
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA damage-induced degradation of Cdc25A does not lead to inhibition of Cdk2 activity in mouse embryonic stem cells.
    Koledova Z; Kafkova LR; Krämer A; Divoky V
    Stem Cells; 2010 Mar; 28(3):450-61. PubMed ID: 20104581
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Serine-Threonine Kinase 38 regulates CDC25A stability and the DNA damage-induced G2/M checkpoint.
    Fukasawa T; Enomoto A; Miyagawa K
    Cell Signal; 2015 Aug; 27(8):1569-75. PubMed ID: 25936524
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chk1, but not Chk2, inhibits Cdc25 phosphatases by a novel common mechanism.
    Uto K; Inoue D; Shimuta K; Nakajo N; Sagata N
    EMBO J; 2004 Aug; 23(16):3386-96. PubMed ID: 15272308
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NEK11 regulates CDC25A degradation and the IR-induced G2/M checkpoint.
    Melixetian M; Klein DK; Sørensen CS; Helin K
    Nat Cell Biol; 2009 Oct; 11(10):1247-53. PubMed ID: 19734889
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68.
    Wei JH; Chou YF; Ou YH; Yeh YH; Tyan SW; Sun TP; Shen CY; Shieh SY
    J Biol Chem; 2005 Mar; 280(9):7748-57. PubMed ID: 15618221
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulatory interactions between the checkpoint kinase Chk1 and the proteins of the DNA-dependent protein kinase complex.
    Goudelock DM; Jiang K; Pereira E; Russell B; Sanchez Y
    J Biol Chem; 2003 Aug; 278(32):29940-7. PubMed ID: 12756247
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control.
    Demidova AR; Aau MY; Zhuang L; Yu Q
    J Biol Chem; 2009 Feb; 284(7):4132-9. PubMed ID: 19060337
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints.
    Zhao H; Watkins JL; Piwnica-Worms H
    Proc Natl Acad Sci U S A; 2002 Nov; 99(23):14795-800. PubMed ID: 12399544
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hierarchical order of phosphorylation events commits Cdc25A to betaTrCP-dependent degradation.
    Donzelli M; Busino L; Chiesa M; Ganoth D; Hershko A; Draetta GF
    Cell Cycle; 2004 Apr; 3(4):469-71. PubMed ID: 14752276
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.