BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 12759434)

  • 1. Uncoupling of promitogenic and antiapoptotic functions of IL-2 by Smad-dependent TGF-beta signaling.
    Nelson BH; Martyak TP; Thompson LJ; Moon JJ; Wang T
    J Immunol; 2003 Jun; 170(11):5563-70. PubMed ID: 12759434
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphatidylinositol 3-kinase potentiates, but does not trigger, T cell proliferation mediated by the IL-2 receptor.
    Moon JJ; Nelson BH
    J Immunol; 2001 Sep; 167(5):2714-23. PubMed ID: 11509615
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Smad3 is essential for TGF-beta 1 to suppress IL-2 production and TCR-induced proliferation, but not IL-2-induced proliferation.
    McKarns SC; Schwartz RH; Kaminski NE
    J Immunol; 2004 Apr; 172(7):4275-84. PubMed ID: 15034041
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Distinct effects of TGF-beta 1 on CD4+ and CD8+ T cell survival, division, and IL-2 production: a role for T cell intrinsic Smad3.
    McKarns SC; Schwartz RH
    J Immunol; 2005 Feb; 174(4):2071-83. PubMed ID: 15699137
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stat5 and Sp1 regulate transcription of the cyclin D2 gene in response to IL-2.
    Martino A; Holmes JH; Lord JD; Moon JJ; Nelson BH
    J Immunol; 2001 Feb; 166(3):1723-9. PubMed ID: 11160217
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5.
    Lord JD; McIntosh BC; Greenberg PD; Nelson BH
    J Immunol; 2000 Mar; 164(5):2533-41. PubMed ID: 10679091
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Suppression of IL-2-induced T cell proliferation and phosphorylation of STAT3 and STAT5 by tumor-derived TGF beta is reversed by IL-15.
    Campbell JD; Cook G; Robertson SE; Fraser A; Boyd KS; Gracie JA; Franklin IM
    J Immunol; 2001 Jul; 167(1):553-61. PubMed ID: 11418694
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transcriptional regulation of the beta-casein gene by cytokines: cross-talk between STAT5 and other signaling molecules.
    Chida D; Wakao H; Yoshimura A; Miyajima A
    Mol Endocrinol; 1998 Nov; 12(11):1792-806. PubMed ID: 9817603
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional uncoupling of the Janus kinase 3-Stat5 pathway in malignant growth of human T cell leukemia virus type 1-transformed human T cells.
    Kirken RA; Erwin RA; Wang L; Wang Y; Rui H; Farrar WL
    J Immunol; 2000 Nov; 165(9):5097-104. PubMed ID: 11046040
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Beta-hydroxybutyrate-induced growth inhibition and collagen production in HK-2 cells are dependent on TGF-beta and Smad3.
    Guh JY; Chuang TD; Chen HC; Hung WC; Lai YH; Shin SJ; Chuang LY
    Kidney Int; 2003 Dec; 64(6):2041-51. PubMed ID: 14633126
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IL-4 selectively inhibits IL-2-triggered Stat5 activation, but not proliferation, in human T cells.
    Castro A; Sengupta TK; Ruiz DC; Yang E; Ivashkiv LB
    J Immunol; 1999 Feb; 162(3):1261-9. PubMed ID: 9973378
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular role of TGF-beta, secreted from a new type of CD4+ suppressor T cell, NY4.2, in the prevention of autoimmune IDDM in NOD mice.
    Han HS; Jun HS; Utsugi T; Yoon JW
    J Autoimmun; 1997 Jun; 10(3):299-307. PubMed ID: 9218758
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The IL-2 receptor promotes proliferation, bcl-2 and bcl-x induction, but not cell viability through the adapter molecule Shc.
    Lord JD; McIntosh BC; Greenberg PD; Nelson BH
    J Immunol; 1998 Nov; 161(9):4627-33. PubMed ID: 9794391
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription.
    Zhang Y; Feng XH; Derynck R
    Nature; 1998 Aug; 394(6696):909-13. PubMed ID: 9732876
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Smad3 has a critical role in TGF-beta-mediated growth inhibition and apoptosis in colonic epithelial cells.
    Mithani SK; Balch GC; Shiou SR; Whitehead RH; Datta PK; Beauchamp RD
    J Surg Res; 2004 Apr; 117(2):296-305. PubMed ID: 15047135
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interleukin-2 inhibits glucocorticoid receptor transcriptional activity through a mechanism involving STAT5 (signal transducer and activator of transcription 5) but not AP-1.
    Biola A; Lefebvre P; Perrin-Wolff M; Sturm M; Bertoglio J; Pallardy M
    Mol Endocrinol; 2001 Jul; 15(7):1062-76. PubMed ID: 11435608
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Repression of Smad-dependent transforming growth factor-beta signaling by Epstein-Barr virus latent membrane protein 1 through nuclear factor-kappaB.
    Mori N; Morishita M; Tsukazaki T; Yamamoto N
    Int J Cancer; 2003 Jul; 105(5):661-8. PubMed ID: 12740915
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutations of the Smad4 gene in acute myelogeneous leukemia and their functional implications in leukemogenesis.
    Imai Y; Kurokawa M; Izutsu K; Hangaishi A; Maki K; Ogawa S; Chiba S; Mitani K; Hirai H
    Oncogene; 2001 Jan; 20(1):88-96. PubMed ID: 11244507
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of IL-2-induced Jak-STAT signaling by glucocorticoids.
    Bianchi M; Meng C; Ivashkiv LB
    Proc Natl Acad Sci U S A; 2000 Aug; 97(17):9573-8. PubMed ID: 10920190
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Concomitant inhibition of Janus kinase 3 and calcineurin-dependent signaling pathways synergistically prolongs the survival of rat heart allografts.
    Behbod F; Erwin-Cohen RA; Wang ME; Trawick BW; Qu X; Verani R; Kahan BD; Stepkowski SM; Kirken RA
    J Immunol; 2001 Mar; 166(6):3724-32. PubMed ID: 11238613
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.