293 related articles for article (PubMed ID: 12761336)
1. Diazonamide A and a synthetic structural analog: disruptive effects on mitosis and cellular microtubules and analysis of their interactions with tubulin.
Cruz-Monserrate Z; Vervoort HC; Bai R; Newman DJ; Howell SB; Los G; Mullaney JT; Williams MD; Pettit GR; Fenical W; Hamel E
Mol Pharmacol; 2003 Jun; 63(6):1273-80. PubMed ID: 12761336
[TBL] [Abstract][Full Text] [Related]
2. Dolastatin 15, a potent antimitotic depsipeptide derived from Dolabella auricularia. Interaction with tubulin and effects of cellular microtubules.
Bai R; Friedman SJ; Pettit GR; Hamel E
Biochem Pharmacol; 1992 Jun; 43(12):2637-45. PubMed ID: 1632820
[TBL] [Abstract][Full Text] [Related]
3. Dolastatin 15 binds in the vinca domain of tubulin as demonstrated by Hummel-Dreyer chromatography.
Cruz-Monserrate Z; Mullaney JT; Harran PG; Pettit GR; Hamel E
Eur J Biochem; 2003 Sep; 270(18):3822-8. PubMed ID: 12950266
[TBL] [Abstract][Full Text] [Related]
4. Spongistatin 1, a highly cytotoxic, sponge-derived, marine natural product that inhibits mitosis, microtubule assembly, and the binding of vinblastine to tubulin.
Bai R; Cichacz ZA; Herald CL; Pettit GR; Hamel E
Mol Pharmacol; 1993 Oct; 44(4):757-66. PubMed ID: 8232226
[TBL] [Abstract][Full Text] [Related]
5. Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain.
Bai R; Pettit GR; Hamel E
Biochem Pharmacol; 1990 Jun; 39(12):1941-9. PubMed ID: 2353935
[TBL] [Abstract][Full Text] [Related]
6. Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data.
Bai RL; Paull KD; Herald CL; Malspeis L; Pettit GR; Hamel E
J Biol Chem; 1991 Aug; 266(24):15882-9. PubMed ID: 1874739
[TBL] [Abstract][Full Text] [Related]
7. LU103793 (NSC D-669356): a synthetic peptide that interacts with microtubules and inhibits mitosis.
de Arruda M; Cocchiaro CA; Nelson CM; Grinnell CM; Janssen B; Haupt A; Barlozzari T
Cancer Res; 1995 Jul; 55(14):3085-92. PubMed ID: 7606731
[TBL] [Abstract][Full Text] [Related]
8. Characterization of the interaction of TZT-1027, a potent antitumor agent, with tubulin.
Natsume T; Watanabe J; Tamaoki S; Fujio N; Miyasaka K; Kobayashi M
Jpn J Cancer Res; 2000 Jul; 91(7):737-47. PubMed ID: 10920282
[TBL] [Abstract][Full Text] [Related]
9. Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites.
Bai RL; Pettit GR; Hamel E
J Biol Chem; 1990 Oct; 265(28):17141-9. PubMed ID: 2211617
[TBL] [Abstract][Full Text] [Related]
10. The spongistatins, potently cytotoxic inhibitors of tubulin polymerization, bind in a distinct region of the vinca domain.
Bai R; Taylor GF; Cichacz ZA; Herald CL; Kepler JA; Pettit GR; Hamel E
Biochemistry; 1995 Aug; 34(30):9714-21. PubMed ID: 7626642
[TBL] [Abstract][Full Text] [Related]
11. Interaction of diazonamide A with tubulin.
Bai R; Cruz-Monserrate Z; Fenical W; Pettit GR; Hamel E
Arch Biochem Biophys; 2020 Feb; 680():108217. PubMed ID: 31830440
[TBL] [Abstract][Full Text] [Related]
12. Differential effects of active isomers, segments, and analogs of dolastatin 10 on ligand interactions with tubulin. Correlation with cytotoxicity.
Bai R; Roach MC; Jayaram SK; Barkoczy J; Pettit GR; Ludueña RF; Hamel E
Biochem Pharmacol; 1993 Apr; 45(7):1503-15. PubMed ID: 8471072
[TBL] [Abstract][Full Text] [Related]
13. The molecular pharmacology of symplostatin 1: a new antimitotic dolastatin 10 analog.
Mooberry SL; Leal RM; Tinley TL; Luesch H; Moore RE; Corbett TH
Int J Cancer; 2003 Apr; 104(4):512-21. PubMed ID: 12584751
[TBL] [Abstract][Full Text] [Related]
14. Chemistry and biology of diazonamide A: second total synthesis and biological investigations.
Nicolaou KC; Hao J; Reddy MV; Rao PB; Rassias G; Snyder SA; Huang X; Chen DY; Brenzovich WE; Giuseppone N; O'Brate A; Giannakakou P
J Am Chem Soc; 2004 Oct; 126(40):12897-906. PubMed ID: 15469287
[TBL] [Abstract][Full Text] [Related]
15. Effects of the antimitotic natural product dolastatin 10, and related peptides, on the human malarial parasite Plasmodium falciparum.
Fennell BJ; Carolan S; Pettit GR; Bell A
J Antimicrob Chemother; 2003 Apr; 51(4):833-41. PubMed ID: 12654761
[TBL] [Abstract][Full Text] [Related]
16. Therapeutic anticancer efficacy of a synthetic diazonamide analog in the absence of overt toxicity.
Williams NS; Burgett AW; Atkins AS; Wang X; Harran PG; McKnight SL
Proc Natl Acad Sci U S A; 2007 Feb; 104(7):2074-9. PubMed ID: 17287337
[TBL] [Abstract][Full Text] [Related]
17. Diazonamide toxins reveal an unexpected function for ornithine delta-amino transferase in mitotic cell division.
Wang G; Shang L; Burgett AW; Harran PG; Wang X
Proc Natl Acad Sci U S A; 2007 Feb; 104(7):2068-73. PubMed ID: 17287350
[TBL] [Abstract][Full Text] [Related]
18. The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity.
Wieczorek M; Tcherkezian J; Bernier C; Prota AE; Chaaban S; Rolland Y; Godbout C; Hancock MA; Arezzo JC; Ocal O; Rocha C; Olieric N; Hall A; Ding H; Bramoullé A; Annis MG; Zogopoulos G; Harran PG; Wilkie TM; Brekken RA; Siegel PM; Steinmetz MO; Shore GC; Brouhard GJ; Roulston A
Sci Transl Med; 2016 Nov; 8(365):365ra159. PubMed ID: 27856798
[TBL] [Abstract][Full Text] [Related]
19. Mechanism of action cryptophycin. Interaction with the Vinca alkaloid domain of tubulin.
Smith CD; Zhang X
J Biol Chem; 1996 Mar; 271(11):6192-8. PubMed ID: 8626409
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of tubulin polymerization by vitilevuamide, a bicyclic marine peptide, at a site distinct from colchicine, the vinca alkaloids, and dolastatin 10.
Edler MC; Fernandez AM; Lassota P; Ireland CM; Barrows LR
Biochem Pharmacol; 2002 Feb; 63(4):707-15. PubMed ID: 11992639
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]