BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

294 related articles for article (PubMed ID: 12761336)

  • 41. MT119, a new planar-structured compound, targets the colchicine site of tubulin arresting mitosis and inhibiting tumor cell proliferation.
    Zhang Z; Meng T; Yang N; Wang W; Xiong B; Chen Y; Ma L; Shen J; Miao ZH; Ding J
    Int J Cancer; 2011 Jul; 129(1):214-24. PubMed ID: 20830720
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Structure-activity studies with chiral isomers and with segments of the antimitotic marine peptide dolastatin 10.
    Bai RL; Pettit GR; Hamel E
    Biochem Pharmacol; 1990 Oct; 40(8):1859-64. PubMed ID: 2242019
    [TBL] [Abstract][Full Text] [Related]  

  • 43. A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors.
    Tahir SK; Han EK; Credo B; Jae HS; Pietenpol JA; Scatena CD; Wu-Wong JR; Frost D; Sham H; Rosenberg SH; Ng SC
    Cancer Res; 2001 Jul; 61(14):5480-5. PubMed ID: 11454695
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Antimitotic peptides and depsipeptides.
    Hamel E; Covell DG
    Curr Med Chem Anticancer Agents; 2002 Jan; 2(1):19-53. PubMed ID: 12678750
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Resveratrol analog (Z)-3,5,4'-trimethoxystilbene is a potent anti-mitotic drug inhibiting tubulin polymerization.
    Schneider Y; Chabert P; Stutzmann J; Coelho D; Fougerousse A; Gossé F; Launay JF; Brouillard R; Raul F
    Int J Cancer; 2003 Nov; 107(2):189-96. PubMed ID: 12949793
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Antitumour evaluation of dolastatins 10 and 15 and their measurement in plasma by radioimmunoassay.
    Aherne GW; Hardcastle A; Valenti M; Bryant A; Rogers P; Pettit GR; Srirangam JK; Kelland LR
    Cancer Chemother Pharmacol; 1996; 38(3):225-32. PubMed ID: 8646796
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Microtubule binding and disruption and induction of premature senescence by disorazole C(1).
    Tierno MB; Kitchens CA; Petrik B; Graham TH; Wipf P; Xu FL; Saunders WS; Raccor BS; Balachandran R; Day BW; Stout JR; Walczak CE; Ducruet AP; Reese CE; Lazo JS
    J Pharmacol Exp Ther; 2009 Mar; 328(3):715-22. PubMed ID: 19066338
    [TBL] [Abstract][Full Text] [Related]  

  • 48. MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules.
    Zhang Z; Meng T; He J; Li M; Tong LJ; Xiong B; Lin L; Shen J; Miao ZH; Ding J
    Invest New Drugs; 2010 Dec; 28(6):715-28. PubMed ID: 19705064
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Discovery of potent cytotoxic ortho-aryl chalcones as new scaffold targeting tubulin and mitosis with affinity-based fluorescence.
    Zhu C; Zuo Y; Wang R; Liang B; Yue X; Wen G; Shang N; Huang L; Chen Y; Du J; Bu X
    J Med Chem; 2014 Aug; 57(15):6364-82. PubMed ID: 25061803
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Synthesis and biological activity of chimeric structures derived from the cytotoxic natural compounds dolastatin 10 and dolastatin 15.
    Poncet J; Busquet M; Roux F; Pierré A; Atassi G; Jouin P
    J Med Chem; 1998 Apr; 41(9):1524-30. PubMed ID: 9554885
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Methylenedioxy-benzopyran analogs of podophyllotoxin, a new synthetic class of antimitotic agents that inhibit tubulin polymerization.
    Batra JK; Kang GJ; Jurd L; Hamel E
    Biochem Pharmacol; 1988 Jul; 37(13):2595-602. PubMed ID: 3390218
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Interaction of ustiloxin A with bovine brain tubulin.
    Ludueńa RF; Roach MC; Prasad V; Banerjee M; Koiso Y; Li Y; Iwasaki S
    Biochem Pharmacol; 1994 Apr; 47(9):1593-9. PubMed ID: 8185673
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Identification of novel antimitotic agents acting at the tubulin level by computer-assisted evaluation of differential cytotoxicity data.
    Paull KD; Lin CM; Malspeis L; Hamel E
    Cancer Res; 1992 Jul; 52(14):3892-900. PubMed ID: 1617665
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Rotenone inhibits mammalian cell proliferation by inhibiting microtubule assembly through tubulin binding.
    Srivastava P; Panda D
    FEBS J; 2007 Sep; 274(18):4788-801. PubMed ID: 17697112
    [TBL] [Abstract][Full Text] [Related]  

  • 55. 3-(Iodoacetamido)-benzoylurea: a novel cancericidal tubulin ligand that inhibits microtubule polymerization, phosphorylates bcl-2, and induces apoptosis in tumor cells.
    Jiang JD; Davis AS; Middleton K; Ling YH; Perez-Soler R; Holland JF; Bekesi JG
    Cancer Res; 1998 Dec; 58(23):5389-95. PubMed ID: 9850070
    [TBL] [Abstract][Full Text] [Related]  

  • 56. The interaction of spongistatin 1 with tubulin.
    Bai R; Smith AB; Pettit GR; Hamel E
    Arch Biochem Biophys; 2022 Sep; 727():109296. PubMed ID: 35594923
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Microtubule-disrupting effects of gallium chloride in vitro.
    Perchellet EM; Ladesich JB; Collery P; Perchellet JP
    Anticancer Drugs; 1999 Jun; 10(5):477-88. PubMed ID: 10477168
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Cornigerine, a potent antimitotic Colchicum alkaloid of unusual structure. Interactions with tubulin.
    Hamel E; Ho HH; Kang GJ; Lin CM
    Biochem Pharmacol; 1988 Jun; 37(12):2445-9. PubMed ID: 3390207
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Laulimalide and paclitaxel: a comparison of their effects on tubulin assembly and their synergistic action when present simultaneously.
    Gapud EJ; Bai R; Ghosh AK; Hamel E
    Mol Pharmacol; 2004 Jul; 66(1):113-21. PubMed ID: 15213302
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Growth inhibition of human lymphoma cell lines by the marine products, dolastatins 10 and 15.
    Beckwith M; Urba WJ; Longo DL
    J Natl Cancer Inst; 1993 Mar; 85(6):483-8. PubMed ID: 8445676
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.