689 related articles for article (PubMed ID: 12764143)
1. Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells.
Mottet D; Dumont V; Deccache Y; Demazy C; Ninane N; Raes M; Michiels C
J Biol Chem; 2003 Aug; 278(33):31277-85. PubMed ID: 12764143
[TBL] [Abstract][Full Text] [Related]
2. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
Blancher C; Moore JW; Robertson N; Harris AL
Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
[TBL] [Abstract][Full Text] [Related]
3. Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3'-kinase/protein kinase B in prostate cancer cells.
Mabjeesh NJ; Willard MT; Frederickson CE; Zhong H; Simons JW
Clin Cancer Res; 2003 Jul; 9(7):2416-25. PubMed ID: 12855613
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of GSK3beta by indirubins restores HIF-1alpha accumulation under prolonged periods of hypoxia/anoxia.
Schnitzer SE; Schmid T; Zhou J; Eisenbrand G; Brüne B
FEBS Lett; 2005 Jan; 579(2):529-33. PubMed ID: 15642371
[TBL] [Abstract][Full Text] [Related]
5. In vitro study of HIF-1 activation and VEGF release by bFGF in the T47D breast cancer cell line under normoxic conditions: involvement of PI-3K/Akt and MEK1/ERK pathways.
Shi YH; Wang YX; Bingle L; Gong LH; Heng WJ; Li Y; Fang WG
J Pathol; 2005 Mar; 205(4):530-6. PubMed ID: 15714461
[TBL] [Abstract][Full Text] [Related]
6. Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of follicular differentiation.
Alam H; Maizels ET; Park Y; Ghaey S; Feiger ZJ; Chandel NS; Hunzicker-Dunn M
J Biol Chem; 2004 May; 279(19):19431-40. PubMed ID: 14982927
[TBL] [Abstract][Full Text] [Related]
7. Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension.
Alvarez-Tejado M; Alfranca A; Aragonés J; Vara A; Landázuri MO; del Peso L
J Biol Chem; 2002 Apr; 277(16):13508-17. PubMed ID: 11815624
[TBL] [Abstract][Full Text] [Related]
8. VEGF production by primary human renal proximal tubular cells: requirement of HIF-1, PI3-kinase and MAPKK-1 signaling.
Hellwig-Bürgel T; Stiehl DP; Katschinski DM; Marxsen J; Kreft B; Jelkmann W
Cell Physiol Biochem; 2005; 15(1-4):99-108. PubMed ID: 15665520
[TBL] [Abstract][Full Text] [Related]
9. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.
Zhong H; Chiles K; Feldser D; Laughner E; Hanrahan C; Georgescu MM; Simons JW; Semenza GL
Cancer Res; 2000 Mar; 60(6):1541-5. PubMed ID: 10749120
[TBL] [Abstract][Full Text] [Related]
10. PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.
Zhou J; Schmid T; Frank R; Brüne B
J Biol Chem; 2004 Apr; 279(14):13506-13. PubMed ID: 14726529
[TBL] [Abstract][Full Text] [Related]
11. Cell cycle kinase inhibitor expression and hypoxia-induced cell cycle arrest in human cancer cell lines.
Box AH; Demetrick DJ
Carcinogenesis; 2004 Dec; 25(12):2325-35. PubMed ID: 15347600
[TBL] [Abstract][Full Text] [Related]
12. Induction of hypoxia-inducible-factor 1 by nitric oxide is mediated via the PI 3K pathway.
Sandau KB; Faus HG; Brüne B
Biochem Biophys Res Commun; 2000 Nov; 278(1):263-7. PubMed ID: 11071882
[TBL] [Abstract][Full Text] [Related]
13. Hypoxia-independent overexpression of hypoxia-inducible factor 1alpha as an early change in mouse hepatocarcinogenesis.
Tanaka H; Yamamoto M; Hashimoto N; Miyakoshi M; Tamakawa S; Yoshie M; Tokusashi Y; Yokoyama K; Yaginuma Y; Ogawa K
Cancer Res; 2006 Dec; 66(23):11263-70. PubMed ID: 17145871
[TBL] [Abstract][Full Text] [Related]
14. Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1alpha, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling.
Skinner HD; Zheng JZ; Fang J; Agani F; Jiang BH
J Biol Chem; 2004 Oct; 279(44):45643-51. PubMed ID: 15337760
[TBL] [Abstract][Full Text] [Related]
15. Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway.
Treins C; Giorgetti-Peraldi S; Murdaca J; Semenza GL; Van Obberghen E
J Biol Chem; 2002 Aug; 277(31):27975-81. PubMed ID: 12032158
[TBL] [Abstract][Full Text] [Related]
16. 4-Hydroxy estradiol but not 2-hydroxy estradiol induces expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor A through phosphatidylinositol 3-kinase/Akt/FRAP pathway in OVCAR-3 and A2780-CP70 human ovarian carcinoma cells.
Gao N; Nester RA; Sarkar MA
Toxicol Appl Pharmacol; 2004 Apr; 196(1):124-35. PubMed ID: 15050414
[TBL] [Abstract][Full Text] [Related]
17. Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1.
Jiang BH; Jiang G; Zheng JZ; Lu Z; Hunter T; Vogt PK
Cell Growth Differ; 2001 Jul; 12(7):363-9. PubMed ID: 11457733
[TBL] [Abstract][Full Text] [Related]
18. Celecoxib Down-Regulates the Hypoxia-Induced Expression of HIF-1α and VEGF Through the PI3K/AKT Pathway in Retinal Pigment Epithelial Cells.
Sun YZ; Cai N; Liu NN
Cell Physiol Biochem; 2017; 44(4):1640-1650. PubMed ID: 29216640
[TBL] [Abstract][Full Text] [Related]
19. HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression.
Laughner E; Taghavi P; Chiles K; Mahon PC; Semenza GL
Mol Cell Biol; 2001 Jun; 21(12):3995-4004. PubMed ID: 11359907
[TBL] [Abstract][Full Text] [Related]
20. Hepatocyte growth factor signalling stimulates hypoxia inducible factor-1 (HIF-1) activity in HepG2 hepatoma cells.
Tacchini L; Dansi P; Matteucci E; Desiderio MA
Carcinogenesis; 2001 Sep; 22(9):1363-71. PubMed ID: 11532856
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
