826 related articles for article (PubMed ID: 1277151)
1. Elevation of dihydrofolate reductase, thymidylate synthetase, and thymidine kinase in cultured mammalian cells after exposure to folate antagonists.
Chello PL; McQueen CA; DeAngelis LM; Bertino JR
Cancer Res; 1976 Jul; 36(7 PT 1):2442-9. PubMed ID: 1277151
[TBL] [Abstract][Full Text] [Related]
2. Effect of methotrexate on thymidylate synthetase in cultured parenchymal cells isolated from regenerating rat liver.
Bonney RJ; Maley F
Cancer Res; 1975 Aug; 35(8):1950-6. PubMed ID: 1170938
[TBL] [Abstract][Full Text] [Related]
3. Thymidylate synthetase levels as a factor in 5-fluorodeoxyuridine and methotrexate cytotoxicity in gastrointestinal tumor cells.
Washtien WL
Mol Pharmacol; 1982 May; 21(3):723-8. PubMed ID: 6213845
[TBL] [Abstract][Full Text] [Related]
4. Cytotoxic effects of folate antagonists against methotrexate-resistant human leukemic lymphoblast CCRF-CEM cell lines.
Mini E; Moroson BA; Franco CT; Bertino JR
Cancer Res; 1985 Jan; 45(1):325-30. PubMed ID: 3855284
[TBL] [Abstract][Full Text] [Related]
5. Thymidylate synthetase and dihydrofolic acid reductase in the stimulated human lymphocyte.
Haurani FI; Kardinal CG; Biermann WA
J Cell Physiol; 1978 Apr; 95(1):49-55. PubMed ID: 147880
[TBL] [Abstract][Full Text] [Related]
6. Determinants of activity of the antifolate thymidylate synthase inhibitors Tomudex (ZD1694) and GW1843U89 against mono- and multilayered colon cancer cell lines under folate-restricted conditions.
Peters GJ; Smitskamp-Wilms E; Smid K; Pinedo HM; Jansen G
Cancer Res; 1999 Nov; 59(21):5529-35. PubMed ID: 10554030
[TBL] [Abstract][Full Text] [Related]
7. Interaction of thymidylate synthetase and dihydrofolate reductase enzymes in vitro and in vivo.
Kawai M; Hillcoat BL
Cancer Res; 1974 Jul; 34(7):1619-26. PubMed ID: 4833915
[No Abstract] [Full Text] [Related]
8. p14ARF expression increases dihydrofolate reductase degradation and paradoxically results in resistance to folate antagonists in cells with nonfunctional p53.
Magro PG; Russo AJ; Li WW; Banerjee D; Bertino JR
Cancer Res; 2004 Jun; 64(12):4338-45. PubMed ID: 15205349
[TBL] [Abstract][Full Text] [Related]
9. LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes.
Shih C; Chen VJ; Gossett LS; Gates SB; MacKellar WC; Habeck LL; Shackelford KA; Mendelsohn LG; Soose DJ; Patel VF; Andis SL; Bewley JR; Rayl EA; Moroson BA; Beardsley GP; Kohler W; Ratnam M; Schultz RM
Cancer Res; 1997 Mar; 57(6):1116-23. PubMed ID: 9067281
[TBL] [Abstract][Full Text] [Related]
10. Quinazoline antifolates as inhibitors of growth, dihydrofolate reductase, and thymidylate synthetase of mouse neuroblastoma cells in culture.
Carlin SC; Rosenberg RN; VandeVenter L; Friedkin M
Mol Pharmacol; 1974 Mar; 10(2):194-203. PubMed ID: 4546895
[No Abstract] [Full Text] [Related]
11. Intrinsic resistance to methotrexate of cultured mammalian cells in relation to the inhibition kinetics of their dihydrololate reductases.
Jackson RC; Hart LI; Harrap KR
Cancer Res; 1976 Jun; 36(6):1991-7. PubMed ID: 5189
[TBL] [Abstract][Full Text] [Related]
12. Synergistic growth inhibition of rat hepatoma cells exposed in vitro to N10-propargyl-5,8-dideazafolate with methotrexate or the lipophilic antifolates trimetrexate or metoprine.
Galivan J; Nimec Z; Rhee M
Cancer Res; 1987 Oct; 47(20):5256-60. PubMed ID: 2958130
[TBL] [Abstract][Full Text] [Related]
13. Biochemical and cellular pharmacology of 1843U89, a novel benzoquinazoline inhibitor of thymidylate synthase.
Duch DS; Banks S; Dev IK; Dickerson SH; Ferone R; Heath LS; Humphreys J; Knick V; Pendergast W; Singer S
Cancer Res; 1993 Feb; 53(4):810-8. PubMed ID: 8428362
[TBL] [Abstract][Full Text] [Related]
14. Increased thymidylate synthase in L1210 cells possessing acquired resistance to N10-propargyl-5,8-dideazafolic acid (CB3717): development, characterization, and cross-resistance studies.
Jackman AL; Alison DL; Calvert AH; Harrap KR
Cancer Res; 1986 Jun; 46(6):2810-5. PubMed ID: 2938731
[TBL] [Abstract][Full Text] [Related]
15. Antifolate polyglutamylation and competitive drug displacement at dihydrofolate reductase as important elements in leucovorin rescue in L1210 cells.
Matherly LH; Barlowe CK; Goldman ID
Cancer Res; 1986 Feb; 46(2):588-93. PubMed ID: 2416428
[TBL] [Abstract][Full Text] [Related]
16. Role of methylenetetrahydrofolate depletion in methotrexate-mediated intracellular thymidylate synthesis inhibition in cultured L1210 cells.
Bunni M; Doig MT; Donato H; Kesavan V; Priest DG
Cancer Res; 1988 Jun; 48(12):3398-404. PubMed ID: 3370638
[TBL] [Abstract][Full Text] [Related]
17. Biochemical and biological studies on 2-desamino-2-methylaminopterin, an antifolate the polyglutamates of which are more potent than the monoglutamate against three key enzymes of folate metabolism.
Rosowsky A; Galivan J; Beardsley GP; Bader H; O'Connor BM; Russello O; Moroson BA; DeYarman MT; Kerwar SS; Freisheim JH
Cancer Res; 1992 Apr; 52(8):2148-55. PubMed ID: 1313737
[TBL] [Abstract][Full Text] [Related]
18. Multifactorial resistance to 5,10-dideazatetrahydrofolic acid in cell lines derived from human lymphoblastic leukemia CCRF-CEM.
Pizzorno G; Moroson BA; Cashmore AR; Russello O; Mayer JR; Galivan J; Bunni MA; Priest DG; Beardsley GP
Cancer Res; 1995 Feb; 55(3):566-73. PubMed ID: 7834626
[TBL] [Abstract][Full Text] [Related]
19. Antifolate drug interactions: enhancement of growth inhibition due to the antipurine 5,10-dideazatetrahydrofolic acid by the lipophilic dihydrofolate reductase inhibitors metoprine and trimetrexate.
Galivan J; Nimec Z; Rhee M; Boschelli D; Oronsky AL; Kerwar SS
Cancer Res; 1988 May; 48(9):2421-5. PubMed ID: 2965613
[TBL] [Abstract][Full Text] [Related]
20. Biochemical effects of a quinazoline inhibitor of thymidylate synthetase, N-(4-(N-(( 2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino) benzoyl)-L-glutamic acid (CB3717), on human lymphoblastoid cells.
Jackson RC; Jackman AL; Calvert AH
Biochem Pharmacol; 1983 Dec; 32(24):3783-90. PubMed ID: 6661252
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
