283 related articles for article (PubMed ID: 12773159)
1. Aspects of tuberous sclerosis complex (TSC) protein function in the brain.
Ramesh V
Biochem Soc Trans; 2003 Jun; 31(Pt 3):579-83. PubMed ID: 12773159
[TBL] [Abstract][Full Text] [Related]
2. Survey of somatic mutations in tuberous sclerosis complex (TSC) hamartomas suggests different genetic mechanisms for pathogenesis of TSC lesions.
Niida Y; Stemmer-Rachamimov AO; Logrip M; Tapon D; Perez R; Kwiatkowski DJ; Sims K; MacCollin M; Louis DN; Ramesh V
Am J Hum Genet; 2001 Sep; 69(3):493-503. PubMed ID: 11468687
[TBL] [Abstract][Full Text] [Related]
3. Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: biallelic inactivation of TSC1 or TSC2 leads to mTOR activation.
Chan JA; Zhang H; Roberts PS; Jozwiak S; Wieslawa G; Lewin-Kowalik J; Kotulska K; Kwiatkowski DJ
J Neuropathol Exp Neurol; 2004 Dec; 63(12):1236-42. PubMed ID: 15624760
[TBL] [Abstract][Full Text] [Related]
4. Tuberous sclerosis as an underlying basis for infantile spasm.
Yeung RS
Int Rev Neurobiol; 2002; 49():315-32. PubMed ID: 12040899
[TBL] [Abstract][Full Text] [Related]
5. Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34.
van Slegtenhorst M; de Hoogt R; Hermans C; Nellist M; Janssen B; Verhoef S; Lindhout D; van den Ouweland A; Halley D; Young J; Burley M; Jeremiah S; Woodward K; Nahmias J; Fox M; Ekong R; Osborne J; Wolfe J; Povey S; Snell RG; Cheadle JP; Jones AC; Tachataki M; Ravine D; Sampson JR; Reeve MP; Richardson P; Wilmer F; Munro C; Hawkins TL; Sepp T; Ali JB; Ward S; Green AJ; Yates JR; Kwiatkowska J; Henske EP; Short MP; Haines JH; Jozwiak S; Kwiatkowski DJ
Science; 1997 Aug; 277(5327):805-8. PubMed ID: 9242607
[TBL] [Abstract][Full Text] [Related]
6. Evidence for separable functions of tuberous sclerosis gene products in mammalian cell cycle regulation.
Miloloza A; Kubista M; Rosner M; Hengstschläger M
J Neuropathol Exp Neurol; 2002 Feb; 61(2):154-63. PubMed ID: 11853018
[TBL] [Abstract][Full Text] [Related]
7. Comprehensive mutation analysis of TSC1 and TSC2-and phenotypic correlations in 150 families with tuberous sclerosis.
Jones AC; Shyamsundar MM; Thomas MW; Maynard J; Idziaszczyk S; Tomkins S; Sampson JR; Cheadle JP
Am J Hum Genet; 1999 May; 64(5):1305-15. PubMed ID: 10205261
[TBL] [Abstract][Full Text] [Related]
8. TSC2 missense mutations inhibit tuberin phosphorylation and prevent formation of the tuberin-hamartin complex.
Nellist M; Verhaaf B; Goedbloed MA; Reuser AJ; van den Ouweland AM; Halley DJ
Hum Mol Genet; 2001 Dec; 10(25):2889-98. PubMed ID: 11741832
[TBL] [Abstract][Full Text] [Related]
9. Localization of tuberous sclerosis 2 mRNA and its protein product tuberin in normal human brain and in cerebral lesions of patients with tuberous sclerosis.
Kerfoot C; Wienecke R; Menchine M; Emelin J; Maize JC; Welsh CT; Norman MG; DeClue JE; Vinters HV
Brain Pathol; 1996 Oct; 6(4):367-75. PubMed ID: 8944308
[TBL] [Abstract][Full Text] [Related]
10. Mutational analysis in a cohort of 224 tuberous sclerosis patients indicates increased severity of TSC2, compared with TSC1, disease in multiple organs.
Dabora SL; Jozwiak S; Franz DN; Roberts PS; Nieto A; Chung J; Choy YS; Reeve MP; Thiele E; Egelhoff JC; Kasprzyk-Obara J; Domanska-Pakiela D; Kwiatkowski DJ
Am J Hum Genet; 2001 Jan; 68(1):64-80. PubMed ID: 11112665
[TBL] [Abstract][Full Text] [Related]
11. Tuberin and hamartin are aberrantly expressed and linked to clinical outcome in human breast cancer: the role of promoter methylation of TSC genes.
Jiang WG; Sampson J; Martin TA; Lee-Jones L; Watkins G; Douglas-Jones A; Mokbel K; Mansel RE
Eur J Cancer; 2005 Jul; 41(11):1628-36. PubMed ID: 15951164
[TBL] [Abstract][Full Text] [Related]
12. Pathological mutations in TSC1 and TSC2 disrupt the interaction between hamartin and tuberin.
Hodges AK; Li S; Maynard J; Parry L; Braverman R; Cheadle JP; DeClue JE; Sampson JR
Hum Mol Genet; 2001 Dec; 10(25):2899-905. PubMed ID: 11741833
[TBL] [Abstract][Full Text] [Related]
13. The expression of hamartin, the product of the TSC1 gene, in normal human tissues and in TSC1- and TSC2-linked angiomyolipomas.
Plank TL; Logginidou H; Klein-Szanto A; Henske EP
Mod Pathol; 1999 May; 12(5):539-45. PubMed ID: 10349994
[TBL] [Abstract][Full Text] [Related]
14. Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products.
van Slegtenhorst M; Nellist M; Nagelkerken B; Cheadle J; Snell R; van den Ouweland A; Reuser A; Sampson J; Halley D; van der Sluijs P
Hum Mol Genet; 1998 Jun; 7(6):1053-7. PubMed ID: 9580671
[TBL] [Abstract][Full Text] [Related]
15. Tuberin phosphorylation regulates its interaction with hamartin. Two proteins involved in tuberous sclerosis.
Aicher LD; Campbell JS; Yeung RS
J Biol Chem; 2001 Jun; 276(24):21017-21. PubMed ID: 11290735
[TBL] [Abstract][Full Text] [Related]
16. Regulation of tuberous sclerosis complex (TSC) function by 14-3-3 proteins.
Nellist M; Goedbloed MA; Halley DJ
Biochem Soc Trans; 2003 Jun; 31(Pt 3):587-91. PubMed ID: 12773161
[TBL] [Abstract][Full Text] [Related]
17. Loss of heterozygosity in the tuberous sclerosis (TSC2) region of chromosome band 16p13 occurs in sporadic as well as TSC-associated renal angiomyolipomas.
Henske EP; Neumann HP; Scheithauer BW; Herbst EW; Short MP; Kwiatkowski DJ
Genes Chromosomes Cancer; 1995 Aug; 13(4):295-8. PubMed ID: 7547639
[TBL] [Abstract][Full Text] [Related]
18. The TSC1 tumor suppressor hamartin interacts with neurofilament-L and possibly functions as a novel integrator of the neuronal cytoskeleton.
Haddad LA; Smith N; Bowser M; Niida Y; Murthy V; Gonzalez-Agosti C; Ramesh V
J Biol Chem; 2002 Nov; 277(46):44180-6. PubMed ID: 12226091
[TBL] [Abstract][Full Text] [Related]
19. Giant cells: contradiction to two-hit model of tuber formation?
Jozwiak J; Jozwiak S
Cell Mol Neurobiol; 2007 Mar; 27(2):251-61. PubMed ID: 16897363
[TBL] [Abstract][Full Text] [Related]
20. Tuberous sclerosis complex: genetics to pathogenesis.
Narayanan V
Pediatr Neurol; 2003 Nov; 29(5):404-9. PubMed ID: 14684235
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]