BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

260 related articles for article (PubMed ID: 12777381)

  • 1. Assembly and topography of the prepore complex in cholesterol-dependent cytolysins.
    Heuck AP; Tweten RK; Johnson AE
    J Biol Chem; 2003 Aug; 278(33):31218-25. PubMed ID: 12777381
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The mechanism of pore assembly for a cholesterol-dependent cytolysin: formation of a large prepore complex precedes the insertion of the transmembrane beta-hairpins.
    Shepard LA; Shatursky O; Johnson AE; Tweten RK
    Biochemistry; 2000 Aug; 39(33):10284-93. PubMed ID: 10956018
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Cholesterol-dependent Cytolysin Membrane-binding Interface Discriminates Lipid Environments of Cholesterol to Support β-Barrel Pore Insertion.
    Farrand AJ; Hotze EM; Sato TK; Wade KR; Wimley WC; Johnson AE; Tweten RK
    J Biol Chem; 2015 Jul; 290(29):17733-17744. PubMed ID: 26032415
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Vertical collapse of a cytolysin prepore moves its transmembrane beta-hairpins to the membrane.
    Czajkowsky DM; Hotze EM; Shao Z; Tweten RK
    EMBO J; 2004 Aug; 23(16):3206-15. PubMed ID: 15297878
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Perfringolysin O structure and mechanism of pore formation as a paradigm for cholesterol-dependent cytolysins.
    Johnson BB; Heuck AP
    Subcell Biochem; 2014; 80():63-81. PubMed ID: 24798008
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The domains of a cholesterol-dependent cytolysin undergo a major FRET-detected rearrangement during pore formation.
    Ramachandran R; Tweten RK; Johnson AE
    Proc Natl Acad Sci U S A; 2005 May; 102(20):7139-44. PubMed ID: 15878993
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Studies on the structure and mechanism of a bacterial protein toxin by analytical ultracentrifugation and small-angle neutron scattering.
    Gilbert RJ; Heenan RK; Timmins PA; Gingles NA; Mitchell TJ; Rowe AJ; Rossjohn J; Parker MW; Andrew PW; Byron O
    J Mol Biol; 1999 Nov; 293(5):1145-60. PubMed ID: 10547292
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The cholesterol-dependent cytolysin family of gram-positive bacterial toxins.
    Heuck AP; Moe PC; Johnson BB
    Subcell Biochem; 2010; 51():551-77. PubMed ID: 20213558
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural insights into the membrane-anchoring mechanism of a cholesterol-dependent cytolysin.
    Ramachandran R; Heuck AP; Tweten RK; Johnson AE
    Nat Struct Biol; 2002 Nov; 9(11):823-7. PubMed ID: 12368903
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Monomer-monomer interactions drive the prepore to pore conversion of a beta-barrel-forming cholesterol-dependent cytolysin.
    Hotze EM; Heuck AP; Czajkowsky DM; Shao Z; Johnson AE; Tweten RK
    J Biol Chem; 2002 Mar; 277(13):11597-605. PubMed ID: 11799121
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Staphylococcal alpha-toxin, streptolysin-O, and Escherichia coli hemolysin: prototypes of pore-forming bacterial cytolysins.
    Bhakdi S; Bayley H; Valeva A; Walev I; Walker B; Kehoe M; Palmer M
    Arch Microbiol; 1996 Feb; 165(2):73-9. PubMed ID: 8593102
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanism of membrane insertion of a multimeric beta-barrel protein: perfringolysin O creates a pore using ordered and coupled conformational changes.
    Heuck AP; Hotze EM; Tweten RK; Johnson AE
    Mol Cell; 2000 Nov; 6(5):1233-42. PubMed ID: 11106760
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Key Motif in the Cholesterol-Dependent Cytolysins Reveals a Large Family of Related Proteins.
    Evans JC; Johnstone BA; Lawrence SL; Morton CJ; Christie MP; Parker MW; Tweten RK
    mBio; 2020 Sep; 11(5):. PubMed ID: 32994330
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Membrane-dependent conformational changes initiate cholesterol-dependent cytolysin oligomerization and intersubunit beta-strand alignment.
    Ramachandran R; Tweten RK; Johnson AE
    Nat Struct Mol Biol; 2004 Aug; 11(8):697-705. PubMed ID: 15235590
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An intermolecular electrostatic interaction controls the prepore-to-pore transition in a cholesterol-dependent cytolysin.
    Wade KR; Hotze EM; Kuiper MJ; Morton CJ; Parker MW; Tweten RK
    Proc Natl Acad Sci U S A; 2015 Feb; 112(7):2204-9. PubMed ID: 25646411
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Arresting pore formation of a cholesterol-dependent cytolysin by disulfide trapping synchronizes the insertion of the transmembrane beta-sheet from a prepore intermediate.
    Hotze EM; Wilson-Kubalek EM; Rossjohn J; Parker MW; Johnson AE; Tweten RK
    J Biol Chem; 2001 Mar; 276(11):8261-8. PubMed ID: 11102453
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The cholesterol-dependent cytolysin signature motif: a critical element in the allosteric pathway that couples membrane binding to pore assembly.
    Dowd KJ; Farrand AJ; Tweten RK
    PLoS Pathog; 2012; 8(7):e1002787. PubMed ID: 22792065
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural studies of Streptococcus pyogenes streptolysin O provide insights into the early steps of membrane penetration.
    Feil SC; Ascher DB; Kuiper MJ; Tweten RK; Parker MW
    J Mol Biol; 2014 Feb; 426(4):785-92. PubMed ID: 24316049
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The cholesterol-dependent cytolysins.
    Tweten RK; Parker MW; Johnson AE
    Curr Top Microbiol Immunol; 2001; 257():15-33. PubMed ID: 11417120
    [TBL] [Abstract][Full Text] [Related]  

  • 20. How cholesterol-dependent cytolysins bite holes into membranes.
    Walz T
    Mol Cell; 2005 May; 18(4):393-4. PubMed ID: 15893721
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.