145 related articles for article (PubMed ID: 12777961)
21. Identification of cytochrome p450 enzymes involved in the metabolism of 4'-methyl-alpha-pyrrolidinopropiophenone, a novel scheduled designer drug, in human liver microsomes.
Springer D; Paul LD; Staack RF; Kraemer T; Maurer HH
Drug Metab Dispos; 2003 Aug; 31(8):979-82. PubMed ID: 12867484
[TBL] [Abstract][Full Text] [Related]
22. Novel binding mode of the acidic CYP2D6 substrates pactimibe and its metabolite R-125528.
Kotsuma M; Hanzawa H; Iwata Y; Takahashi K; Tokui T
Drug Metab Dispos; 2008 Sep; 36(9):1938-43. PubMed ID: 18524873
[TBL] [Abstract][Full Text] [Related]
23. Identification of human cytochrome P450 2D6 as major enzyme involved in the O-demethylation of the designer drug p-methoxymethamphetamine.
Staack RF; Theobald DS; Paul LD; Springer D; Kraemer T; Maurer HH
Drug Metab Dispos; 2004 Apr; 32(4):379-81. PubMed ID: 15039289
[TBL] [Abstract][Full Text] [Related]
24. Mechanism-based inactivation of CYP2D6 by methylenedioxymethamphetamine.
Heydari A; Yeo KR; Lennard MS; Ellis SW; Tucker GT; Rostami-Hodjegan A
Drug Metab Dispos; 2004 Nov; 32(11):1213-7. PubMed ID: 15328252
[TBL] [Abstract][Full Text] [Related]
25. Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6.
Yamaori S; Okamoto Y; Yamamoto I; Watanabe K
Drug Metab Dispos; 2011 Nov; 39(11):2049-56. PubMed ID: 21821735
[TBL] [Abstract][Full Text] [Related]
26. Catalyzation of cocaine N-demethylation by cytochromes P4502B, P4503A, and P4502D in fish liver.
Arinç E; Bozcaarmutlu A
J Biochem Mol Toxicol; 2003; 17(3):169-76. PubMed ID: 12815613
[TBL] [Abstract][Full Text] [Related]
27. Identification of human cytochrome p450 isozymes involved in diphenhydramine N-demethylation.
Akutsu T; Kobayashi K; Sakurada K; Ikegaya H; Furihata T; Chiba K
Drug Metab Dispos; 2007 Jan; 35(1):72-8. PubMed ID: 17020955
[TBL] [Abstract][Full Text] [Related]
28. The impact of experimental design on assessing mechanism-based inactivation of CYP2D6 by MDMA (Ecstasy).
Van LM; Heydari A; Yang J; Hargreaves J; Rowland-Yeo K; Lennard MS; Tucker GT; Rostami-Hodjegan A
J Psychopharmacol; 2006 Nov; 20(6):834-41. PubMed ID: 16478752
[TBL] [Abstract][Full Text] [Related]
29. Biotransformation of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes.
Yao HT; Wu YS; Chang YW; Hsieh HP; Chen WC; Lan SJ; Chen CT; Chao YS; Chang L; Sun HY; Yeh TK
Drug Metab Dispos; 2007 Jul; 35(7):1042-9. PubMed ID: 17403915
[TBL] [Abstract][Full Text] [Related]
30. Effect of sodium ozagrel on the activity of rat CYP2D6.
Wu H; Yu W; Huang L; Wang J; Tang X; Yang W; Liu Y; Yu H; Zhu D
Eur J Pharmacol; 2007 Nov; 573(1-3):55-9. PubMed ID: 17651725
[TBL] [Abstract][Full Text] [Related]
31. Functional analysis of CYP2D6.31 variant: homology modeling suggests possible disruption of redox partner interaction by Arg440His substitution.
Allorge D; Bréant D; Harlow J; Chowdry J; Lo-Guidice JM; Chevalier D; Cauffiez C; Lhermitte M; Blaney FE; Tucker GT; Broly F; Ellis SW
Proteins; 2005 May; 59(2):339-46. PubMed ID: 15726636
[TBL] [Abstract][Full Text] [Related]
32. Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes.
Yamanaka H; Nakajima M; Katoh M; Kanoh A; Tamura O; Ishibashi H; Yokoi T
Drug Metab Dispos; 2005 Jan; 33(1):23-30. PubMed ID: 15470160
[TBL] [Abstract][Full Text] [Related]
33. Autoradiographic localization of [3H]-pinoline binding sites in mouse tissues.
Pähkla R; Masso R; Zilmer M; Rägo L; Airaksinen MM
Methods Find Exp Clin Pharmacol; 1996; 18(6):359-66. PubMed ID: 8892265
[TBL] [Abstract][Full Text] [Related]
34. Polymorphic cytochrome P450 2D6: humanized mouse model and endogenous substrates.
Yu AM; Idle JR; Gonzalez FJ
Drug Metab Rev; 2004 May; 36(2):243-77. PubMed ID: 15237854
[TBL] [Abstract][Full Text] [Related]
35. Recombinant production of human microsomal cytochrome P450 2D6 in the methylotrophic yeast Pichia pastoris.
Dietrich M; Grundmann L; Kurr K; Valinotto L; Saussele T; Schmid RD; Lange S
Chembiochem; 2005 Nov; 6(11):2014-22. PubMed ID: 16222729
[TBL] [Abstract][Full Text] [Related]
36. Brain chemistry: how does P450 catalyze the O-demethylation reaction of 5-methoxytryptamine to yield serotonin?
Schyman P; Usharani D; Wang Y; Shaik S
J Phys Chem B; 2010 May; 114(20):7078-89. PubMed ID: 20405876
[TBL] [Abstract][Full Text] [Related]
37. LC-MS/MS analysis of dextromethorphan metabolism in human saliva and urine to determine CYP2D6 phenotype and individual variability in N-demethylation and glucuronidation.
Lutz U; Völkel W; Lutz RW; Lutz WK
J Chromatogr B Analyt Technol Biomed Life Sci; 2004 Dec; 813(1-2):217-25. PubMed ID: 15556536
[TBL] [Abstract][Full Text] [Related]
38. Kinetics of the time-dependent inactivation of CYP2D6 in cryopreserved human hepatocytes by methylenedioxymethamphetamine (MDMA).
Van LM; Swales J; Hammond C; Wilson C; Hargreaves JA; Rostami-Hodjegan A
Eur J Pharm Sci; 2007 May; 31(1):53-61. PubMed ID: 17387004
[TBL] [Abstract][Full Text] [Related]
39. Importance of amine pKa and distribution coefficient in the metabolism of fluorinated propranolol derivatives. Preparation, identification of metabolite regioisomers, and metabolism by CYP2D6.
Upthagrove AL; Nelson WL
Drug Metab Dispos; 2001 Nov; 29(11):1377-88. PubMed ID: 11602512
[TBL] [Abstract][Full Text] [Related]
40. A real-time fluorescence assay for measuring N-dealkylation.
Mayer RT; Dolence EK; Mayer GE
Drug Metab Dispos; 2007 Jan; 35(1):103-9. PubMed ID: 17035601
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
