186 related articles for article (PubMed ID: 12781628)
1. Characterisation of some cytotoxic endpoints using rat liver and HepG2 spheroids as in vitro models and their application in hepatotoxicity studies. I. Glucose metabolism and enzyme release as cytotoxic markers.
Xu J; Ma M; Purcell WM
Toxicol Appl Pharmacol; 2003 Jun; 189(2):100-11. PubMed ID: 12781628
[TBL] [Abstract][Full Text] [Related]
2. Characterisation of some cytotoxic endpoints using rat liver and HepG2 spheroids as in vitro models and their application in hepatotoxicity studies. II. Spheroid cell spreading inhibition as a new cytotoxic marker.
Xu J; Ma M; Purcell WM
Toxicol Appl Pharmacol; 2003 Jun; 189(2):112-9. PubMed ID: 12781629
[TBL] [Abstract][Full Text] [Related]
3. Energy metabolism and biotransformation as endpoints to pre-screen hepatotoxicity using a liver spheroid model.
Xu J; Purcell WM
Toxicol Appl Pharmacol; 2006 Oct; 216(2):293-302. PubMed ID: 16828827
[TBL] [Abstract][Full Text] [Related]
4. Utility of human hepatocyte spheroids without feeder cells for evaluation of hepatotoxicity.
Ogihara T; Arakawa H; Jomura T; Idota Y; Koyama S; Yano K; Kojima H
J Toxicol Sci; 2017; 42(4):499-507. PubMed ID: 28717109
[TBL] [Abstract][Full Text] [Related]
5. Biochemical and functional changes of rat liver spheroids during spheroid formation and maintenance in culture: I. morphological maturation and kinetic changes of energy metabolism, albumin synthesis, and activities of some enzymes.
Ma M; Xu J; Purcell WM
J Cell Biochem; 2003 Dec; 90(6):1166-75. PubMed ID: 14635190
[TBL] [Abstract][Full Text] [Related]
6. A sub-chronic Xysmalobium undulatum hepatotoxicity investigation in HepG2/C3A spheroid cultures compared to an in vivo model.
Calitz C; Hamman JH; Fey SJ; Viljoen AM; Gouws C; Wrzesinski K
J Ethnopharmacol; 2019 Jul; 239():111897. PubMed ID: 31009705
[TBL] [Abstract][Full Text] [Related]
7. Integrated in vitro models for hepatic safety and metabolism: evaluation of a human Liver-Chip and liver spheroid.
Foster AJ; Chouhan B; Regan SL; Rollison H; Amberntsson S; Andersson LC; Srivastava A; Darnell M; Cairns J; Lazic SE; Jang KJ; Petropolis DB; Kodella K; Rubins JE; Williams D; Hamilton GA; Ewart L; Morgan P
Arch Toxicol; 2019 Apr; 93(4):1021-1037. PubMed ID: 30915487
[TBL] [Abstract][Full Text] [Related]
8. Characterizing the reproducibility in using a liver microphysiological system for assaying drug toxicity, metabolism, and accumulation.
Rubiano A; Indapurkar A; Yokosawa R; Miedzik A; Rosenzweig B; Arefin A; Moulin CM; Dame K; Hartman N; Volpe DA; Matta MK; Hughes DJ; Strauss DG; Kostrzewski T; Ribeiro AJS
Clin Transl Sci; 2021 May; 14(3):1049-1061. PubMed ID: 33382907
[TBL] [Abstract][Full Text] [Related]
9. Advantages of in vitro cytotoxicity testing by using primary rat hepatocytes in comparison with established cell lines.
Wang K; Shindoh H; Inoue T; Horii I
J Toxicol Sci; 2002 Aug; 27(3):229-37. PubMed ID: 12238146
[TBL] [Abstract][Full Text] [Related]
10. Vitamin C protects against in vitro cytotoxicity of cypermethrin in rat hepatocytes.
Grajeda-Cota P; Ramírez-Mares MV; González de Mejía E
Toxicol In Vitro; 2004 Feb; 18(1):13-9. PubMed ID: 14630057
[TBL] [Abstract][Full Text] [Related]
11. High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening.
O'Brien PJ; Irwin W; Diaz D; Howard-Cofield E; Krejsa CM; Slaughter MR; Gao B; Kaludercic N; Angeline A; Bernardi P; Brain P; Hougham C
Arch Toxicol; 2006 Sep; 80(9):580-604. PubMed ID: 16598496
[TBL] [Abstract][Full Text] [Related]
12. Glucose and lipid metabolism screening models of hepatocyte spheroids after culture with injectable fiber fragments.
Wei J; Xia T; Chen W; Ran P; Chen M; Li X
J Tissue Eng Regen Med; 2020 Jun; 14(6):774-788. PubMed ID: 32285997
[TBL] [Abstract][Full Text] [Related]
13. Towards a more representative in vitro method for fish ecotoxicology: morphological and biochemical characterisation of three-dimensional spheroidal hepatocytes.
Baron MG; Purcell WM; Jackson SK; Owen SF; Jha AN
Ecotoxicology; 2012 Nov; 21(8):2419-29. PubMed ID: 22732941
[TBL] [Abstract][Full Text] [Related]
14. Metabolic profiling of the effects of D-galactosamine in liver spheroids using (1)H NMR and MAS-NMR spectroscopy.
Bollard ME; Xu J; Purcell W; Griffin JL; Quirk C; Holmes E; Nicholson JK
Chem Res Toxicol; 2002 Nov; 15(11):1351-9. PubMed ID: 12437325
[TBL] [Abstract][Full Text] [Related]
15. The toxicological relevance of paracetamol-induced inhibition of hepatic respiration and ATP depletion.
Strubelt O; Younes M
Biochem Pharmacol; 1992 Jul; 44(1):163-70. PubMed ID: 1632830
[TBL] [Abstract][Full Text] [Related]
16. Antioxidant and hepatoprotective activity of Fagonia schweinfurthii (Hadidi) Hadidi extract in carbon tetrachloride induced hepatotoxicity in HepG2 cell line and rats.
Pareek A; Godavarthi A; Issarani R; Nagori BP
J Ethnopharmacol; 2013 Dec; 150(3):973-81. PubMed ID: 24140589
[TBL] [Abstract][Full Text] [Related]
17. Cytotoxic and cytoprotective activities of curcumin. Effects on paracetamol-induced cytotoxicity, lipid peroxidation and glutathione depletion in rat hepatocytes.
Donatus IA; Sardjoko ; Vermeulen NP
Biochem Pharmacol; 1990 Jun; 39(12):1869-75. PubMed ID: 2353930
[TBL] [Abstract][Full Text] [Related]
18. Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell-Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Systems for Drug-Induced Liver Injury.
Bell CC; Lauschke VM; Vorrink SU; Palmgren H; Duffin R; Andersson TB; Ingelman-Sundberg M
Drug Metab Dispos; 2017 Apr; 45(4):419-429. PubMed ID: 28137721
[TBL] [Abstract][Full Text] [Related]
19. Intracellular lactate dehydrogenase concentration as an index of cytotoxicity in rat hepatocyte primary culture.
Chao ES; Dunbar D; Kaminsky LS
Cell Biol Toxicol; 1988 Mar; 4(1):1-11. PubMed ID: 3228704
[TBL] [Abstract][Full Text] [Related]
20. Studies on the age-dependent effects of galactosamine in primary rat hepatocyte cultures.
Abdul-Hussain SK; Mehendale HM
Toxicol Appl Pharmacol; 1991 Mar; 107(3):504-13. PubMed ID: 2000637
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
