BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

316 related articles for article (PubMed ID: 12785787)

  • 1. Aminoglycoside complexation with a DNA.RNA hybrid duplex: the thermodynamics of recognition and inhibition of RNA processing enzymes.
    Barbieri CM; Li TK; Guo S; Wang G; Shallop AJ; Pan W; Yang G; Gaffney BL; Jones RA; Pilch DS
    J Am Chem Soc; 2003 May; 125(21):6469-77. PubMed ID: 12785787
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Drug targeting of HIV-1 RNA.DNA hybrid structures: thermodynamics of recognition and impact on reverse transcriptase-mediated ribonuclease H activity and viral replication.
    Li TK; Barbieri CM; Lin HC; Rabson AB; Yang G; Fan Y; Gaffney BL; Jones RA; Pilch DS
    Biochemistry; 2004 Aug; 43(30):9732-42. PubMed ID: 15274628
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aminoglycoside binding in the major groove of duplex RNA: the thermodynamic and electrostatic forces that govern recognition.
    Jin E; Katritch V; Olson WK; Kharatisvili M; Abagyan R; Pilch DS
    J Mol Biol; 2000 Apr; 298(1):95-110. PubMed ID: 10756107
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Thermodynamics of aminoglycoside-rRNA recognition: the binding of neomycin-class aminoglycosides to the A site of 16S rRNA.
    Kaul M; Pilch DS
    Biochemistry; 2002 Jun; 41(24):7695-706. PubMed ID: 12056901
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure, recognition properties, and flexibility of the DNA.RNA hybrid.
    Noy A; Pérez A; Márquez M; Luque FJ; Orozco M
    J Am Chem Soc; 2005 Apr; 127(13):4910-20. PubMed ID: 15796556
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RNase H1 can catalyze RNA/DNA hybrid formation and cleavage with stable hairpin or duplex DNA oligomers.
    Li J; Wartell RM
    Biochemistry; 1998 Apr; 37(15):5154-61. PubMed ID: 9548746
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Efficient stabilization of phosphodiester (PO), phosphorothioate (PS), and 2'-O-methoxy (2'-OMe) DNA·RNA hybrid duplexes by amino sugars.
    Charles I; Davis E; Arya DP
    Biochemistry; 2012 Jul; 51(27):5496-505. PubMed ID: 22639785
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparison of the RNase H cleavage kinetics and blood serum stability of the north-conformationally constrained and 2'-alkoxy modified oligonucleotides.
    Honcharenko D; Barman J; Varghese OP; Chattopadhyaya J
    Biochemistry; 2007 May; 46(19):5635-46. PubMed ID: 17411072
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Binding affinity and specificity of Escherichia coli RNase H1: impact on the kinetics of catalysis of antisense oligonucleotide-RNA hybrids.
    Lima WF; Crooke ST
    Biochemistry; 1997 Jan; 36(2):390-8. PubMed ID: 9003192
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Conformation of formacetal and 3'-thioformacetal nucleotide linkers and stability of their antisense RNA.DNA hybrid duplexes.
    Rice JS; Gao X
    Biochemistry; 1997 Jan; 36(2):399-411. PubMed ID: 9003193
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hybrid oligomer duplexes formed with phosphorothioate DNAs: CD spectra and melting temperatures of S-DNA.RNA hybrids are sequence-dependent but consistent with similar heteronomous conformations.
    Hashem GM; Pham L; Vaughan MR; Gray DM
    Biochemistry; 1998 Jan; 37(1):61-72. PubMed ID: 9425026
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular recognition of a DNA:RNA hybrid: sub-nanomolar binding by a neomycin-methidium conjugate.
    Shaw NN; Xi H; Arya DP
    Bioorg Med Chem Lett; 2008 Jul; 18(14):4142-5. PubMed ID: 18573660
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Influences of ribonucleotide on a duplex conformation and its thermal stability: study with the chimeric RNA-DNA strands.
    Nakano S; Kanzaki T; Sugimoto N
    J Am Chem Soc; 2004 Feb; 126(4):1088-95. PubMed ID: 14746477
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Minimum sequence requirements for the binding of paromomycin to the rRNA decoding site A.
    Anderson PC; Mecozzi S
    Biopolymers; 2007 Jun; 86(2):95-111. PubMed ID: 17323326
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The impact of an exocyclic cytosine adduct on DNA duplex properties: significant thermodynamic consequences despite modest lesion-induced structural alterations.
    Gelfand CA; Plum GE; Grollman AP; Johnson F; Breslauer KJ
    Biochemistry; 1998 Sep; 37(36):12507-12. PubMed ID: 9730823
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Duplex stability of DNA.DNA and DNA.RNA duplexes containing 3'-S-phosphorothiolate linkages.
    Bentley J; Brazier JA; Fisher J; Cosstick R
    Org Biomol Chem; 2007 Nov; 5(22):3698-702. PubMed ID: 17972000
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chemically modified oligonucleotides with efficient RNase H response.
    Vester B; Boel AM; Lobedanz S; Babu BR; Raunkjaer M; Lindegaard D; Raunak ; Hrdlicka PJ; Højland T; Sharma PK; Kumar S; Nielsen P; Wengel J
    Bioorg Med Chem Lett; 2008 Apr; 18(7):2296-300. PubMed ID: 18356048
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular dynamics simulations of a r(GA12G).d(CT12C) hybrid duplex.
    Fritsch V; Wolf RM
    J Biomol Struct Dyn; 1994 Jun; 11(6):1161-74. PubMed ID: 7524540
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular requirements for duplex recognition and cleavage by eukaryotic RNase III: discovery of an RNA-dependent DNA cleavage activity of yeast Rnt1p.
    Lamontagne B; Hannoush RN; Damha MJ; Abou Elela S
    J Mol Biol; 2004 Apr; 338(2):401-18. PubMed ID: 15066440
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thermodynamics of DNA-RNA heteroduplex formation: effects of locked nucleic acid nucleotides incorporated into the DNA strand.
    Kaur H; Wengel J; Maiti S
    Biochemistry; 2008 Jan; 47(4):1218-27. PubMed ID: 18171024
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.