503 related articles for article (PubMed ID: 12788921)
1. Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor.
Hirsilä M; Koivunen P; Günzler V; Kivirikko KI; Myllyharju J
J Biol Chem; 2003 Aug; 278(33):30772-80. PubMed ID: 12788921
[TBL] [Abstract][Full Text] [Related]
2. Characterization of a second Arabidopsis thaliana prolyl 4-hydroxylase with distinct substrate specificity.
Tiainen P; Myllyharju J; Koivunen P
J Biol Chem; 2005 Jan; 280(2):1142-8. PubMed ID: 15528200
[TBL] [Abstract][Full Text] [Related]
3. Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.
Koivunen P; Hirsilä M; Günzler V; Kivirikko KI; Myllyharju J
J Biol Chem; 2004 Mar; 279(11):9899-904. PubMed ID: 14701857
[TBL] [Abstract][Full Text] [Related]
4. An endoplasmic reticulum transmembrane prolyl 4-hydroxylase is induced by hypoxia and acts on hypoxia-inducible factor alpha.
Koivunen P; Tiainen P; Hyvärinen J; Williams KE; Sormunen R; Klaus SJ; Kivirikko KI; Myllyharju J
J Biol Chem; 2007 Oct; 282(42):30544-52. PubMed ID: 17726031
[TBL] [Abstract][Full Text] [Related]
5. Many amino acid substitutions in a hypoxia-inducible transcription factor (HIF)-1alpha-like peptide cause only minor changes in its hydroxylation by the HIF prolyl 4-hydroxylases: substitution of 3,4-dehydroproline or azetidine-2-carboxylic acid for the proline leads to a high rate of uncoupled 2-oxoglutarate decarboxylation.
Li D; Hirsilä M; Koivunen P; Brenner MC; Xu L; Yang C; Kivirikko KI; Myllyharju J
J Biol Chem; 2004 Dec; 279(53):55051-9. PubMed ID: 15485863
[TBL] [Abstract][Full Text] [Related]
6. A conserved family of prolyl-4-hydroxylases that modify HIF.
Bruick RK; McKnight SL
Science; 2001 Nov; 294(5545):1337-40. PubMed ID: 11598268
[TBL] [Abstract][Full Text] [Related]
7. The length of peptide substrates has a marked effect on hydroxylation by the hypoxia-inducible factor prolyl 4-hydroxylases.
Koivunen P; Hirsilä M; Kivirikko KI; Myllyharju J
J Biol Chem; 2006 Sep; 281(39):28712-20. PubMed ID: 16885164
[TBL] [Abstract][Full Text] [Related]
8. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor.
Appelhoff RJ; Tian YM; Raval RR; Turley H; Harris AL; Pugh CW; Ratcliffe PJ; Gleadle JM
J Biol Chem; 2004 Sep; 279(37):38458-65. PubMed ID: 15247232
[TBL] [Abstract][Full Text] [Related]
9. Cloning and characterization of a low molecular weight prolyl 4-hydroxylase from Arabidopsis thaliana. Effective hydroxylation of proline-rich, collagen-like, and hypoxia-inducible transcription factor alpha-like peptides.
Hieta R; Myllyharju J
J Biol Chem; 2002 Jun; 277(26):23965-71. PubMed ID: 11976332
[TBL] [Abstract][Full Text] [Related]
10. HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia.
Berra E; Benizri E; Ginouvès A; Volmat V; Roux D; Pouysségur J
EMBO J; 2003 Aug; 22(16):4082-90. PubMed ID: 12912907
[TBL] [Abstract][Full Text] [Related]
11. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of hypoxia-inducible factor (HIF) hydroxylases by citric acid cycle intermediates: possible links between cell metabolism and stabilization of HIF.
Koivunen P; Hirsilä M; Remes AM; Hassinen IE; Kivirikko KI; Myllyharju J
J Biol Chem; 2007 Feb; 282(7):4524-4532. PubMed ID: 17182618
[TBL] [Abstract][Full Text] [Related]
13. Determination and comparison of specific activity of the HIF-prolyl hydroxylases.
Tuckerman JR; Zhao Y; Hewitson KS; Tian YM; Pugh CW; Ratcliffe PJ; Mole DR
FEBS Lett; 2004 Oct; 576(1-2):145-50. PubMed ID: 15474027
[TBL] [Abstract][Full Text] [Related]
14. Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors.
Aprelikova O; Chandramouli GV; Wood M; Vasselli JR; Riss J; Maranchie JK; Linehan WM; Barrett JC
J Cell Biochem; 2004 Jun; 92(3):491-501. PubMed ID: 15156561
[TBL] [Abstract][Full Text] [Related]
15. Activation of hypoxia-induced transcription in normoxia.
Hägg M; Wennström S
Exp Cell Res; 2005 May; 306(1):180-91. PubMed ID: 15878343
[TBL] [Abstract][Full Text] [Related]
16. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation.
Epstein AC; Gleadle JM; McNeill LA; Hewitson KS; O'Rourke J; Mole DR; Mukherji M; Metzen E; Wilson MI; Dhanda A; Tian YM; Masson N; Hamilton DL; Jaakkola P; Barstead R; Hodgkin J; Maxwell PH; Pugh CW; Schofield CJ; Ratcliffe PJ
Cell; 2001 Oct; 107(1):43-54. PubMed ID: 11595184
[TBL] [Abstract][Full Text] [Related]
17. Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3.
Huang J; Zhao Q; Mooney SM; Lee FS
J Biol Chem; 2002 Oct; 277(42):39792-800. PubMed ID: 12181324
[TBL] [Abstract][Full Text] [Related]
18. Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation.
D'Angelo G; Duplan E; Boyer N; Vigne P; Frelin C
J Biol Chem; 2003 Oct; 278(40):38183-7. PubMed ID: 12876291
[TBL] [Abstract][Full Text] [Related]
19. Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway.
Hirsilä M; Koivunen P; Xu L; Seeley T; Kivirikko KI; Myllyharju J
FASEB J; 2005 Aug; 19(10):1308-10. PubMed ID: 15941769
[TBL] [Abstract][Full Text] [Related]
20. Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing.
Metzen E; Berchner-Pfannschmidt U; Stengel P; Marxsen JH; Stolze I; Klinger M; Huang WQ; Wotzlaw C; Hellwig-Bürgel T; Jelkmann W; Acker H; Fandrey J
J Cell Sci; 2003 Apr; 116(Pt 7):1319-26. PubMed ID: 12615973
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
