147 related articles for article (PubMed ID: 12796721)
1. The Ras inhibitor S-trans, trans-farnesylthiosalicylic acid exerts long-lasting neuroprotection in a mouse closed head injury model.
Shohami E; Yatsiv I; Alexandrovich A; Haklai R; Elad-Sfadia G; Grossman R; Biegon A; Kloog Y
J Cereb Blood Flow Metab; 2003 Jun; 23(6):728-38. PubMed ID: 12796721
[TBL] [Abstract][Full Text] [Related]
2. New derivatives of farnesylthiosalicylic acid (salirasib) for cancer treatment: farnesylthiosalicylamide inhibits tumor growth in nude mice models.
Goldberg L; Haklai R; Bauer V; Heiss A; Kloog Y
J Med Chem; 2009 Jan; 52(1):197-205. PubMed ID: 19072665
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of intimal thickening in the rat carotid artery injury model by a nontoxic Ras inhibitor.
George J; Sack J; Barshack I; Keren P; Goldberg I; Haklai R; Elad-Sfadia G; Kloog Y; Keren G
Arterioscler Thromb Vasc Biol; 2004 Feb; 24(2):363-8. PubMed ID: 14670932
[TBL] [Abstract][Full Text] [Related]
4. Neuroprotective effects of the Ras inhibitor S-trans-trans-farnesylthiosalicylic acid, measured by diffusion-weighted imaging after traumatic brain injury in rats.
Marciano D; Shohami E; Kloog Y; Alexandrovitch A; Brandeis R; Goelman G
J Neurotrauma; 2007 Aug; 24(8):1378-86. PubMed ID: 17711399
[TBL] [Abstract][Full Text] [Related]
5. The Ras inhibitor farnesylthiosalicylic acid as a potential therapy for neurofibromatosis type 1.
Barkan B; Starinsky S; Friedman E; Stein R; Kloog Y
Clin Cancer Res; 2006 Sep; 12(18):5533-42. PubMed ID: 17000690
[TBL] [Abstract][Full Text] [Related]
6. Ras inhibitor S-trans, trans-farnesylthiosalicylic acid enhances spatial memory and hippocampal long-term potentiation via up-regulation of NMDA receptor.
Wang Y; Chen T; Yuan Z; Zhang Y; Zhang B; Zhao L; Chen L
Neuropharmacology; 2018 Sep; 139():257-267. PubMed ID: 29578035
[TBL] [Abstract][Full Text] [Related]
7. Ras inhibition attenuates myocardial ischemia-reperfusion injury.
Pando R; Cheporko Y; Haklai R; Maysel-Auslender S; Keren G; George J; Porat E; Sagie A; Kloog Y; Hochhauser E
Biochem Pharmacol; 2009 May; 77(10):1593-601. PubMed ID: 19426696
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of the Ras oncoprotein reduces proliferation of hepatocytes in vitro and in vivo in rats.
da Silva Morais A; Saliez A; Leclercq I; Horsmans Y; Stärkel P
Clin Sci (Lond); 2008 Jan; 114(1):73-83. PubMed ID: 17678500
[TBL] [Abstract][Full Text] [Related]
9. The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer.
Rotblat B; Ehrlich M; Haklai R; Kloog Y
Methods Enzymol; 2008; 439():467-89. PubMed ID: 18374183
[TBL] [Abstract][Full Text] [Related]
10. Ras inhibition increases the frequency and function of regulatory T cells and attenuates type-1 diabetes in non-obese diabetic mice.
Mor A; Kloog Y; Keren G; George J
Eur J Pharmacol; 2009 Aug; 616(1-3):301-5. PubMed ID: 19527709
[TBL] [Abstract][Full Text] [Related]
11. Hitting Ras where it counts: Ras antagonism in the basolateral amygdala inhibits long-term fear memory.
Merino SM; Maren S
Eur J Neurosci; 2006 Jan; 23(1):196-204. PubMed ID: 16420429
[TBL] [Abstract][Full Text] [Related]
12. The Ras antagonist farnesylthiosalicylic acid ameliorates experimental myocarditis in the rat.
Pando R; Barshack I; Raz A; Luboshits G; Haklai R; Maysel-Auslender S; Kloog Y; Keren G; George J
Cardiovasc Pathol; 2010; 19(2):94-101. PubMed ID: 19144546
[TBL] [Abstract][Full Text] [Related]
13. Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death.
Blum R; Jacob-Hirsch J; Amariglio N; Rechavi G; Kloog Y
Cancer Res; 2005 Feb; 65(3):999-1006. PubMed ID: 15705901
[TBL] [Abstract][Full Text] [Related]
14. Gene expression signature of human cancer cell lines treated with the ras inhibitor salirasib (S-farnesylthiosalicylic acid).
Blum R; Elkon R; Yaari S; Zundelevich A; Jacob-Hirsch J; Rechavi G; Shamir R; Kloog Y
Cancer Res; 2007 Apr; 67(7):3320-8. PubMed ID: 17409441
[TBL] [Abstract][Full Text] [Related]
15. D-cycloserine improves functional recovery and reinstates long-term potentiation (LTP) in a mouse model of closed head injury.
Yaka R; Biegon A; Grigoriadis N; Simeonidou C; Grigoriadis S; Alexandrovich AG; Matzner H; Schumann J; Trembovler V; Tsenter J; Shohami E
FASEB J; 2007 Jul; 21(9):2033-41. PubMed ID: 17351125
[TBL] [Abstract][Full Text] [Related]
16. Ras inhibition in hepatocarcinoma by S-trans-trans-farnesylthiosalicyclic acid: association of its tumor preventive effect with cell proliferation, cell cycle events, and angiogenesis.
Stärkel P; Charette N; Borbath I; Schneider-Merck T; De Saeger C; Abarca J; Leclercq I; Horsmans Y
Mol Carcinog; 2012 Oct; 51(10):816-25. PubMed ID: 21882255
[TBL] [Abstract][Full Text] [Related]
17. The influence of the peptide NAP on Mac-1-deficient mice following closed head injury.
Zaltzman R; Alexandrovich A; Trembovler V; Shohami E; Gozes I
Peptides; 2005 Aug; 26(8):1520-7. PubMed ID: 16042992
[TBL] [Abstract][Full Text] [Related]
18. Farnesylthiosalicylic acid induces caspase activation and apoptosis in glioblastoma cells.
Amos S; Redpath GT; Polar G; McPheson R; Schiff D; Hussaini IM
Cell Death Differ; 2006 Apr; 13(4):642-51. PubMed ID: 16239932
[TBL] [Abstract][Full Text] [Related]
19. Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuroprotective effects of IL-18-binding protein after experimental closed head injury.
Yatsiv I; Morganti-Kossmann MC; Perez D; Dinarello CA; Novick D; Rubinstein M; Otto VI; Rancan M; Kossmann T; Redaelli CA; Trentz O; Shohami E; Stahel PF
J Cereb Blood Flow Metab; 2002 Aug; 22(8):971-8. PubMed ID: 12172382
[TBL] [Abstract][Full Text] [Related]
20. Neuroprotective Effect of S-trans, Trans-farnesylthiosalicylic Acid via Inhibition of RAS/ERK Pathway for the Treatment of Alzheimer's Disease.
Wang X; Wang Y; Zhu Y; Yan L; Zhao L
Drug Des Devel Ther; 2019; 13():4053-4063. PubMed ID: 31819374
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]