These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
863 related articles for article (PubMed ID: 12801228)
1. The most potent organophosphorus inhibitors of leucine aminopeptidase. Structure-based design, chemistry, and activity. Grembecka J; Mucha A; Cierpicki T; Kafarski P J Med Chem; 2003 Jun; 46(13):2641-55. PubMed ID: 12801228 [TBL] [Abstract][Full Text] [Related]
2. A synthetic method for diversification of the P1' substituent in phosphinic dipeptides as a tool for exploration of the specificity of the S1' binding pockets of leucine aminopeptidases. Vassiliou S; Xeilari M; Yiotakis A; Grembecka J; Pawełczak M; Kafarski P; Mucha A Bioorg Med Chem; 2007 May; 15(9):3187-200. PubMed ID: 17337192 [TBL] [Abstract][Full Text] [Related]
3. alpha-Aminoalkylphosphonates as a tool in experimental optimisation of P1 side chain shape of potential inhibitors in S1 pocket of leucine- and neutral aminopeptidases. Drag M; Grembecka J; Pawełczak M; Kafarski P Eur J Med Chem; 2005 Aug; 40(8):764-71. PubMed ID: 16122579 [TBL] [Abstract][Full Text] [Related]
4. Identification of phosphinate dipeptide analog inhibitors directed against the Plasmodium falciparum M17 leucine aminopeptidase as lead antimalarial compounds. Skinner-Adams TS; Lowther J; Teuscher F; Stack CM; Grembecka J; Mucha A; Kafarski P; Trenholme KR; Dalton JP; Gardiner DL J Med Chem; 2007 Nov; 50(24):6024-31. PubMed ID: 17960925 [TBL] [Abstract][Full Text] [Related]
5. In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug design. Costanzo MJ; Almond HR; Hecker LR; Schott MR; Yabut SC; Zhang HC; Andrade-Gordon P; Corcoran TW; Giardino EC; Kauffman JA; Lewis JM; de Garavilla L; Haertlein BJ; Maryanoff BE J Med Chem; 2005 Mar; 48(6):1984-2008. PubMed ID: 15771442 [TBL] [Abstract][Full Text] [Related]
6. Novel hydroxamic acid-related phosphinates: inhibition of neutral aminopeptidase N (APN). Drag M; Grzywa R; Oleksyszyn J Bioorg Med Chem Lett; 2007 Mar; 17(6):1516-9. PubMed ID: 17270439 [TBL] [Abstract][Full Text] [Related]
7. [Affinity labeling of leucine aminopeptidase with new substrate analog inhibitors]. Fittkau S; Schunck WH; Mootsi S Acta Biol Med Ger; 1976; 35(3-4):365-78. PubMed ID: 970045 [TBL] [Abstract][Full Text] [Related]
8. A phosphonamidate containing aromatic N-terminal amino group as inhibitor of leucine aminopeptidase-design, synthesis and stability. Mucha A; Kunert A; Grembecka J; Pawełczak M; Kafarski P Eur J Med Chem; 2006 Jun; 41(6):768-72. PubMed ID: 16690170 [TBL] [Abstract][Full Text] [Related]
9. Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity. Devadas B; Freeman SK; Zupec ME; Lu HF; Nagarajan SR; Kishore NS; Lodge JK; Kuneman DW; McWherter CA; Vinjamoori DV; Getman DP; Gordon JI; Sikorski JA J Med Chem; 1997 Aug; 40(16):2609-25. PubMed ID: 9258368 [TBL] [Abstract][Full Text] [Related]
10. First synthesis of alpha-aminoalkyl-(N-substituted)thiocarbamoyl-phosphinates: inhibitors of aminopeptidase N (APN/CD13) with the new zinc-binding group. Grzywa R; Oleksyszyn J Bioorg Med Chem Lett; 2008 Jul; 18(13):3734-6. PubMed ID: 18524593 [TBL] [Abstract][Full Text] [Related]
11. A novel amino-benzosuberone derivative is a picomolar inhibitor of mammalian aminopeptidase N/CD13. Maiereanu C; Schmitt C; Schifano-Faux N; Le Nouën D; Defoin A; Tarnus C Bioorg Med Chem; 2011 Sep; 19(18):5716-33. PubMed ID: 21843945 [TBL] [Abstract][Full Text] [Related]
12. Binding structure of the leucine aminopeptidase inhibitor microginin FR1. Kraft M; Schleberger C; Weckesser J; Schulz GE FEBS Lett; 2006 Dec; 580(30):6943-7. PubMed ID: 17157838 [TBL] [Abstract][Full Text] [Related]
13. A structural insight into the P1S1 binding mode of diaminoethylphosphonic and phosphinic acids, selective inhibitors of alanine aminopeptidases. Węglarz-Tomczak E; Berlicki Ł; Pawełczak M; Nocek B; Joachimiak A; Mucha A Eur J Med Chem; 2016 Jul; 117():187-96. PubMed ID: 27100031 [TBL] [Abstract][Full Text] [Related]
14. Individual stereoisomers of phosphinic dipeptide inhibitor of leucine aminopeptidase. Mucha A; Lämmerhofer M; Lindner W; Pawełczak M; Kafarski P Bioorg Med Chem Lett; 2008 Mar; 18(5):1550-4. PubMed ID: 18262419 [TBL] [Abstract][Full Text] [Related]
16. Biochemical characterization and structural prediction of a novel cytosolic leucyl aminopeptidase of the M17 family from Schizosaccharomyces pombe. Herrera-Camacho I; Rosas-Murrieta NH; Rojo-Domínguez A; Millán L; Reyes-Leyva J; Santos-López G; Suárez-Rendueles P FEBS J; 2007 Dec; 274(23):6228-40. PubMed ID: 18028193 [TBL] [Abstract][Full Text] [Related]
17. Crystal structure of the leucine aminopeptidase from Pseudomonas putida reveals the molecular basis for its enantioselectivity and broad substrate specificity. Kale A; Pijning T; Sonke T; Dijkstra BW; Thunnissen AM J Mol Biol; 2010 May; 398(5):703-14. PubMed ID: 20359484 [TBL] [Abstract][Full Text] [Related]
18. Unusual activity pattern of leucine aminopeptidase inhibitors based on phosphorus containing derivatives of methionine and norleucine. Pícha J; Liboska R; Buděšínský M; Jiráček J; Pawełczak M; Mucha A J Enzyme Inhib Med Chem; 2011 Apr; 26(2):155-61. PubMed ID: 20578976 [TBL] [Abstract][Full Text] [Related]
19. Design, synthesis, and evaluation of novel organophosphorus inhibitors of bacterial ureases. Vassiliou S; Grabowiecka A; Kosikowska P; Yiotakis A; Kafarski P; Berlicki Ł J Med Chem; 2008 Sep; 51(18):5736-44. PubMed ID: 18717581 [TBL] [Abstract][Full Text] [Related]
20. T-state inhibitors of E. coli aspartate transcarbamoylase that prevent the allosteric transition. Heng S; Stieglitz KA; Eldo J; Xia J; Cardia JP; Kantrowitz ER Biochemistry; 2006 Aug; 45(33):10062-71. PubMed ID: 16906764 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]