382 related articles for article (PubMed ID: 12807357)
1. Effect of halogenated substituents on the metabolism and estrogenic effects of the equine estrogen, equilenin.
Liu X; Zhang F; Liu H; Burdette JE; Li Y; Overk CR; Pisha E; Yao J; van Breemen RB; Swanson SM; Bolton JL
Chem Res Toxicol; 2003 Jun; 16(6):741-9. PubMed ID: 12807357
[TBL] [Abstract][Full Text] [Related]
2. The major metabolite of equilin, 4-hydroxyequilin, autoxidizes to an o-quinone which isomerizes to the potent cytotoxin 4-hydroxyequilenin-o-quinone.
Zhang F; Chen Y; Pisha E; Shen L; Xiong Y; van Breemen RB; Bolton JL
Chem Res Toxicol; 1999 Feb; 12(2):204-13. PubMed ID: 10027800
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of glutathione S-transferase activity by the quinoid metabolites of equine estrogens.
Chang M; Zhang F; Shen L; Pauss N; Alam I; van Breemen RB; Blond SY; Bolton JL
Chem Res Toxicol; 1998 Jul; 11(7):758-65. PubMed ID: 9671538
[TBL] [Abstract][Full Text] [Related]
4. Equine estrogen metabolite 4-hydroxyequilenin induces anchorage-independent growth of human mammary epithelial MCF-10A cells: differential gene expression.
Cuendet M; Liu X; Pisha E; Li Y; Yao J; Yu L; Bolton JL
Mutat Res; 2004 Jun; 550(1-2):109-21. PubMed ID: 15135645
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of the equine estrogen metabolites 2-hydroxyequilin and 2-hydroxyequilenin.
Zhang F; Bolton JL
Chem Res Toxicol; 1999 Feb; 12(2):200-3. PubMed ID: 10027799
[TBL] [Abstract][Full Text] [Related]
6. Antiestrogenic and DNA damaging effects induced by tamoxifen and toremifene metabolites.
Liu X; Pisha E; Tonetti DA; Yao D; Li Y; Yao J; Burdette JE; Bolton JL
Chem Res Toxicol; 2003 Jul; 16(7):832-7. PubMed ID: 12870885
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and reactivity of the catechol metabolites from the equine estrogen, 8,9-dehydroestrone.
Zhang F; Yao D; Hua Y; van Breemen RB; Bolton JL
Chem Res Toxicol; 2001 Jun; 14(6):754-63. PubMed ID: 11409947
[TBL] [Abstract][Full Text] [Related]
8. Steroidal affinity labels of the estrogen receptor. 3. Estradiol 11 beta-n-alkyl derivatives bearing a terminal electrophilic group: antiestrogenic and cytotoxic properties.
Lobaccaro C; Pons JF; Duchesne MJ; Auzou G; Pons M; Nique F; Teutsch G; Borgna JL
J Med Chem; 1997 Jul; 40(14):2217-27. PubMed ID: 9216841
[TBL] [Abstract][Full Text] [Related]
9. Equine estrogen metabolite 4-hydroxyequilenin induces DNA damage in the rat mammary tissues: formation of single-strand breaks, apurinic sites, stable adducts, and oxidized bases.
Zhang F; Swanson SM; van Breemen RB; Liu X; Yang Y; Gu C; Bolton JL
Chem Res Toxicol; 2001 Dec; 14(12):1654-9. PubMed ID: 11743748
[TBL] [Abstract][Full Text] [Related]
10. Catechol estrogen 4-hydroxyequilenin is a substrate and an inhibitor of catechol-O-methyltransferase.
Yao J; Li Y; Chang M; Wu H; Yang X; Goodman JE; Liu X; Liu H; Mesecar AD; Van Breemen RB; Yager JD; Bolton JL
Chem Res Toxicol; 2003 May; 16(5):668-75. PubMed ID: 12755597
[TBL] [Abstract][Full Text] [Related]
11. Bioreductive activation of catechol estrogen-ortho-quinones: aromatization of the B ring in 4-hydroxyequilenin markedly alters quinoid formation and reactivity.
Shen L; Pisha E; Huang Z; Pezzuto JM; Krol E; Alam Z; van Breemen RB; Bolton JL
Carcinogenesis; 1997 May; 18(5):1093-101. PubMed ID: 9163701
[TBL] [Abstract][Full Text] [Related]
12. A metabolite of equine estrogens, 4-hydroxyequilenin, induces DNA damage and apoptosis in breast cancer cell lines.
Chen Y; Liu X; Pisha E; Constantinou AI; Hua Y; Shen L; van Breemen RB; Elguindi EC; Blond SY; Zhang F; Bolton JL
Chem Res Toxicol; 2000 May; 13(5):342-50. PubMed ID: 10813650
[TBL] [Abstract][Full Text] [Related]
13. Dietary genistein results in larger MNU-induced, estrogen-dependent mammary tumors following ovariectomy of Sprague-Dawley rats.
Allred CD; Allred KF; Ju YH; Clausen LM; Doerge DR; Schantz SL; Korol DL; Wallig MA; Helferich WG
Carcinogenesis; 2004 Feb; 25(2):211-8. PubMed ID: 14578162
[TBL] [Abstract][Full Text] [Related]
14. The naphthol selective estrogen receptor modulator (SERM), LY2066948, is oxidized to an o-quinone analogous to the naphthol equine estrogen, equilenin.
Gherezghiher TB; Michalsen B; Chandrasena RE; Qin Z; Sohn J; Thatcher GR; Bolton JL
Chem Biol Interact; 2012 Mar; 196(1-2):1-10. PubMed ID: 22290292
[TBL] [Abstract][Full Text] [Related]
15. Hydroxylated polychlorinated biphenyls (PCBs) as estrogens and antiestrogens: structure-activity relationships.
Connor K; Ramamoorthy K; Moore M; Mustain M; Chen I; Safe S; Zacharewski T; Gillesby B; Joyeux A; Balaguer P
Toxicol Appl Pharmacol; 1997 Jul; 145(1):111-23. PubMed ID: 9221830
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and evaluation of B-, C-, and D-ring-substituted estradiol carboxylic acid esters as locally active estrogens.
Labaree DC; Zhang JX; Harris HA; O'Connor C; Reynolds TY; Hochberg RB
J Med Chem; 2003 May; 46(10):1886-904. PubMed ID: 12723952
[TBL] [Abstract][Full Text] [Related]
17. The equine estrogen metabolite 4-hydroxyequilenin causes DNA single-strand breaks and oxidation of DNA bases in vitro.
Chen Y; Shen L; Zhang F; Lau SS; van Breemen RB; Nikolic D; Bolton JL
Chem Res Toxicol; 1998 Sep; 11(9):1105-11. PubMed ID: 9760286
[TBL] [Abstract][Full Text] [Related]
18. Oxidative DNA damage induced by equine estrogen metabolites: role of estrogen receptor alpha.
Liu X; Yao J; Pisha E; Yang Y; Hua Y; van Breemen RB; Bolton JL
Chem Res Toxicol; 2002 Apr; 15(4):512-9. PubMed ID: 11952337
[TBL] [Abstract][Full Text] [Related]
19. Equine catechol estrogen 4-hydroxyequilenin is a more potent inhibitor of the variant form of catechol-O-methyltransferase.
Li Y; Yao J; Chang M; Nikolic D; Yu L; Yager JD; Mesecar AD; van Breemen RB; Bolton JL
Chem Res Toxicol; 2004 Apr; 17(4):512-20. PubMed ID: 15089093
[TBL] [Abstract][Full Text] [Related]
20. Altered apoptotic response in MCF 10A cells treated with the equine estrogen metabolite, 4-hydroxyequilenin.
Li Y; Yao J; Chang M; Cuendet M; Bolton JL
Toxicol Lett; 2004 Dec; 154(3):225-33. PubMed ID: 15501614
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
