BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 12808067)

  • 1. Analysis of the PI-3-Kinase-PTEN-AKT pathway in human lymphoma and leukemia using a cell line microarray.
    Abbott RT; Tripp S; Perkins SL; Elenitoba-Johnson KS; Lim MS
    Mod Pathol; 2003 Jun; 16(6):607-12. PubMed ID: 12808067
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PTEN reverses MDM2-mediated chemotherapy resistance by interacting with p53 in acute lymphoblastic leukemia cells.
    Zhou M; Gu L; Findley HW; Jiang R; Woods WG
    Cancer Res; 2003 Oct; 63(19):6357-62. PubMed ID: 14559824
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells.
    Asano T; Yao Y; Zhu J; Li D; Abbruzzese JL; Reddy SA
    Oncogene; 2004 Nov; 23(53):8571-80. PubMed ID: 15467756
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Akt regulates COX-2 mRNA and protein expression in mutated-PTEN human endometrial cancer cells.
    St-Germain ME; Gagnon V; Mathieu I; Parent S; Asselin E
    Int J Oncol; 2004 May; 24(5):1311-24. PubMed ID: 15067356
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Abnormal PTEN expression in portal hypertensive gastric mucosa: a key to impaired PI 3-kinase/Akt activation and delayed injury healing?
    Tsugawa K; Jones MK; Akahoshi T; Moon WS; Maehara Y; Hashizume M; Sarfeh IJ; Tarnawski AS
    FASEB J; 2003 Dec; 17(15):2316-8. PubMed ID: 14525948
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line.
    Lee S; Choi EJ; Jin C; Kim DH
    Gynecol Oncol; 2005 Apr; 97(1):26-34. PubMed ID: 15790433
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1.
    Ozes ON; Akca H; Mayo LD; Gustin JA; Maehama T; Dixon JE; Donner DB
    Proc Natl Acad Sci U S A; 2001 Apr; 98(8):4640-5. PubMed ID: 11287630
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Preferential killing of PTEN-null myelomas by PI3K inhibitors through Akt pathway.
    Zhang J; Choi Y; Mavromatis B; Lichtenstein A; Li W
    Oncogene; 2003 Sep; 22(40):6289-95. PubMed ID: 13679867
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma.
    Pene F; Claessens YE; Muller O; Viguié F; Mayeux P; Dreyfus F; Lacombe C; Bouscary D
    Oncogene; 2002 Sep; 21(43):6587-97. PubMed ID: 12242656
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN.
    Pianetti S; Arsura M; Romieu-Mourez R; Coffey RJ; Sonenshein GE
    Oncogene; 2001 Mar; 20(11):1287-99. PubMed ID: 11313873
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The role of PTEN and its signalling pathways, including AKT, in breast cancer; an assessment of relationships with other prognostic factors and with outcome.
    Panigrahi AR; Pinder SE; Chan SY; Paish EC; Robertson JF; Ellis IO
    J Pathol; 2004 Sep; 204(1):93-100. PubMed ID: 15307142
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein.
    Paramio JM; Navarro M; Segrelles C; Gómez-Casero E; Jorcano JL
    Oncogene; 1999 Dec; 18(52):7462-8. PubMed ID: 10602505
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Loss of PTEN expression leading to high Akt activation in human multiple myelomas.
    Hyun T; Yam A; Pece S; Xie X; Zhang J; Miki T; Gutkind JS; Li W
    Blood; 2000 Nov; 96(10):3560-8. PubMed ID: 11071655
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells.
    Choi Y; Zhang J; Murga C; Yu H; Koller E; Monia BP; Gutkind JS; Li W
    Oncogene; 2002 Aug; 21(34):5289-300. PubMed ID: 12149650
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway.
    Seo JH; Ahn Y; Lee SR; Yeol Yeo C; Chung Hur K
    Mol Biol Cell; 2005 Jan; 16(1):348-57. PubMed ID: 15537704
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer.
    Yuan ZQ; Sun M; Feldman RI; Wang G; Ma X; Jiang C; Coppola D; Nicosia SV; Cheng JQ
    Oncogene; 2000 May; 19(19):2324-30. PubMed ID: 10822383
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The inducible expression of the tumor suppressor gene PTEN promotes apoptosis and decreases cell size by inhibiting the PI3K/Akt pathway in Jurkat T cells.
    Xu Z; Stokoe D; Kane LP; Weiss A
    Cell Growth Differ; 2002 Jul; 13(7):285-96. PubMed ID: 12133897
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway.
    Wu X; Senechal K; Neshat MS; Whang YE; Sawyers CL
    Proc Natl Acad Sci U S A; 1998 Dec; 95(26):15587-91. PubMed ID: 9861013
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of sensitivity to TRAIL by the PTEN tumor suppressor.
    Whang YE; Yuan XJ; Liu Y; Majumder S; Lewis TD
    Vitam Horm; 2004; 67():409-26. PubMed ID: 15110188
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Impact of PTEN on the expression of insulin-like growth factors (IGFs) and IGF-binding proteins in human gastric adenocarcinoma cells.
    Yi HK; Kim SY; Hwang PH; Kim CY; Yang DH; Oh Y; Lee DY
    Biochem Biophys Res Commun; 2005 May; 330(3):760-7. PubMed ID: 15809062
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.