BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

423 related articles for article (PubMed ID: 12810655)

  • 1. The different biological effects of telomestatin and TMPyP4 can be attributed to their selectivity for interaction with intramolecular or intermolecular G-quadruplex structures.
    Kim MY; Gleason-Guzman M; Izbicka E; Nishioka D; Hurley LH
    Cancer Res; 2003 Jun; 63(12):3247-56. PubMed ID: 12810655
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Binding of G-quadruplex-interactive agents to distinct G-quadruplexes induces different biological effects in MiaPaCa cells.
    Liu W; Sun D; Hurley LH
    Nucleosides Nucleotides Nucleic Acids; 2005; 24(10-12):1801-15. PubMed ID: 16438049
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex.
    Kim MY; Vankayalapati H; Shin-Ya K; Wierzba K; Hurley LH
    J Am Chem Soc; 2002 Mar; 124(10):2098-9. PubMed ID: 11878947
    [TBL] [Abstract][Full Text] [Related]  

  • 4. G-Quadruplex stabilization by telomestatin induces TRF2 protein dissociation from telomeres and anaphase bridge formation accompanied by loss of the 3' telomeric overhang in cancer cells.
    Tahara H; Shin-Ya K; Seimiya H; Yamada H; Tsuruo T; Ide T
    Oncogene; 2006 Mar; 25(13):1955-66. PubMed ID: 16302000
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A G-quadruplex-interactive agent, telomestatin (SOT-095), induces telomere shortening with apoptosis and enhances chemosensitivity in acute myeloid leukemia.
    Sumi M; Tauchi T; Sashida G; Nakajima A; Gotoh A; Shin-Ya K; Ohyashiki JH; Ohyashiki K
    Int J Oncol; 2004 Jun; 24(6):1481-7. PubMed ID: 15138591
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure.
    Rezler EM; Seenisamy J; Bashyam S; Kim MY; White E; Wilson WD; Hurley LH
    J Am Chem Soc; 2005 Jul; 127(26):9439-47. PubMed ID: 15984871
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Telomerase inhibition, telomere shortening, cell growth suppression and induction of apoptosis by telomestatin in childhood neuroblastoma cells.
    Binz N; Shalaby T; Rivera P; Shin-ya K; Grotzer MA
    Eur J Cancer; 2005 Dec; 41(18):2873-81. PubMed ID: 16253503
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Telomerase inhibitor, telomestatin, a specific mechanism to interact with telomere structure].
    Shin-ya K
    Nihon Rinsho; 2004 Jul; 62(7):1277-82. PubMed ID: 15283144
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Telomere-interactive agents affect proliferation rates and induce chromosomal destabilization in sea urchin embryos.
    Izbicka E; Nishioka D; Marcell V; Raymond E; Davidson KK; Lawrence RA; Wheelhouse RT; Hurley LH; Wu RS; Von Hoff DD
    Anticancer Drug Des; 1999 Aug; 14(4):355-65. PubMed ID: 10625928
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Affinity and selectivity of G4 ligands measured by FRET.
    De Cian A; Guittat L; Shin-ya K; Riou JF; Mergny JL
    Nucleic Acids Symp Ser (Oxf); 2005; (49):235-6. PubMed ID: 17150720
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cells.
    Izbicka E; Wheelhouse RT; Raymond E; Davidson KK; Lawrence RA; Sun D; Windle BE; Hurley LH; Von Hoff DD
    Cancer Res; 1999 Feb; 59(3):639-44. PubMed ID: 9973212
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stabilization of the c-myc gene promoter quadruplex by specific ligands' inhibitors of telomerase.
    Lemarteleur T; Gomez D; Paterski R; Mandine E; Mailliet P; Riou JF
    Biochem Biophys Res Commun; 2004 Oct; 323(3):802-8. PubMed ID: 15381071
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents.
    Sun D; Guo K; Rusche JJ; Hurley LH
    Nucleic Acids Res; 2005; 33(18):6070-80. PubMed ID: 16239639
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: in vitro and in vivo studies in acute leukemia.
    Tauchi T; Shin-ya K; Sashida G; Sumi M; Okabe S; Ohyashiki JH; Ohyashiki K
    Oncogene; 2006 Sep; 25(42):5719-25. PubMed ID: 16652154
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Energetics of the human Tel-22 quadruplex-telomestatin interaction: a molecular dynamics study.
    Agrawal S; Ojha RP; Maiti S
    J Phys Chem B; 2008 Jun; 112(22):6828-36. PubMed ID: 18461983
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of telomere and telomerase interactive agents on human tumor and normal cell lines.
    Rha SY; Izbicka E; Lawrence R; Davidson K; Sun D; Moyer MP; Roodman GD; Hurley L; Von Hoff D
    Clin Cancer Res; 2000 Mar; 6(3):987-93. PubMed ID: 10741725
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase.
    Gomez D; Aouali N; Renaud A; Douarre C; Shin-Ya K; Tazi J; Martinez S; Trentesaux C; Morjani H; Riou JF
    Cancer Res; 2003 Oct; 63(19):6149-53. PubMed ID: 14559794
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Studying telomere replication by Q-CO-FISH: the effect of telomestatin, a potent G-quadruplex ligand.
    Arnoult N; Shin-Ya K; LondoƱo-Vallejo JA
    Cytogenet Genome Res; 2008; 122(3-4):229-36. PubMed ID: 19188691
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sequence specificity of inter- and intramolecular G-quadruplex formation by human telomeric DNA.
    Pedroso IM; Duarte LF; Yanez G; Burkewitz K; Fletcher TM
    Biopolymers; 2007 Sep; 87(1):74-84. PubMed ID: 17549693
    [TBL] [Abstract][Full Text] [Related]  

  • 20. G-quadruplexes as therapeutic targets.
    Neidle S; Read MA
    Biopolymers; 2000-2001; 56(3):195-208. PubMed ID: 11745111
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.