BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

517 related articles for article (PubMed ID: 12810709)

  • 1. Ligand-dependent inhibition of B16 melanoma cell migration and invasion via endogenous S1P2 G protein-coupled receptor. Requirement of inhibition of cellular RAC activity.
    Arikawa K; Takuwa N; Yamaguchi H; Sugimoto N; Kitayama J; Nagawa H; Takehara K; Takuwa Y
    J Biol Chem; 2003 Aug; 278(35):32841-51. PubMed ID: 12810709
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibitory and stimulatory regulation of Rac and cell motility by the G12/13-Rho and Gi pathways integrated downstream of a single G protein-coupled sphingosine-1-phosphate receptor isoform.
    Sugimoto N; Takuwa N; Okamoto H; Sakurada S; Takuwa Y
    Mol Cell Biol; 2003 Mar; 23(5):1534-45. PubMed ID: 12588974
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and haematogenous metastasis of melanoma cells.
    Yamaguchi H; Kitayama J; Takuwa N; Arikawa K; Inoki I; Takehara K; Nagawa H; Takuwa Y
    Biochem J; 2003 Sep; 374(Pt 3):715-22. PubMed ID: 12803545
    [TBL] [Abstract][Full Text] [Related]  

  • 4. G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase.
    Takashima S; Sugimoto N; Takuwa N; Okamoto Y; Yoshioka K; Takamura M; Takata S; Kaneko S; Takuwa Y
    Cardiovasc Res; 2008 Sep; 79(4):689-97. PubMed ID: 18480127
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3.
    Okamoto H; Takuwa N; Yokomizo T; Sugimoto N; Sakurada S; Shigematsu H; Takuwa Y
    Mol Cell Biol; 2000 Dec; 20(24):9247-61. PubMed ID: 11094076
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sphingosine-1-phosphate, a platelet-derived lysophospholipid mediator, negatively regulates cellular Rac activity and cell migration in vascular smooth muscle cells.
    Ryu Y; Takuwa N; Sugimoto N; Sakurada S; Usui S; Okamoto H; Matsui O; Takuwa Y
    Circ Res; 2002 Feb; 90(3):325-32. PubMed ID: 11861422
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The G protein-coupled receptor S1P2 regulates Rho/Rho kinase pathway to inhibit tumor cell migration.
    Lepley D; Paik JH; Hla T; Ferrer F
    Cancer Res; 2005 May; 65(9):3788-95. PubMed ID: 15867375
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Testosterone regulates the expression and functional activity of sphingosine-1-phosphate receptors in the rat corpus cavernosum.
    Yin J; Guo YM; Chen P; Xiao H; Wang XH; DiSanto ME; Zhang XH
    J Cell Mol Med; 2018 Mar; 22(3):1507-1516. PubMed ID: 29266713
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Extracellular mechanism through the Edg family of receptors might be responsible for sphingosine-1-phosphate-induced regulation of DNA synthesis and migration of rat aortic smooth-muscle cells.
    Tamama K; Kon J; Sato K; Tomura H; Kuwabara A; Kimura T; Kanda T; Ohta H; Ui M; Kobayashi I; Okajima F
    Biochem J; 2001 Jan; 353(Pt 1):139-146. PubMed ID: 11115407
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparison of sphingosine 1-phosphate-induced intracellular signaling pathways in vascular smooth muscles: differential role in vasoconstriction.
    Coussin F; Scott RH; Wise A; Nixon GF
    Circ Res; 2002 Jul; 91(2):151-7. PubMed ID: 12142348
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN.
    Sanchez T; Skoura A; Wu MT; Casserly B; Harrington EO; Hla T
    Arterioscler Thromb Vasc Biol; 2007 Jun; 27(6):1312-8. PubMed ID: 17431187
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selective coupling of the S1P
    Yung BS; Brand CS; Xiang SY; Gray CB; Means CK; Rosen H; Chun J; Purcell NH; Brown JH; Miyamoto S
    J Mol Cell Cardiol; 2017 Feb; 103():1-10. PubMed ID: 28017639
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prostacyclin induction by high-density lipoprotein (HDL) in vascular smooth muscle cells depends on sphingosine 1-phosphate receptors: effect of simvastatin.
    González-Díez M; Rodríguez C; Badimon L; Martínez-González J
    Thromb Haemost; 2008 Jul; 100(1):119-26. PubMed ID: 18612546
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sphingosine 1-phosphate elicits RhoA-dependent proliferation and MRTF-A mediated gene induction in CPCs.
    Castaldi A; Chesini GP; Taylor AE; Sussman MA; Brown JH; Purcell NH
    Cell Signal; 2016 Aug; 28(8):871-9. PubMed ID: 27094722
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sphingosine-1-phosphate receptor subtypes differentially regulate smooth muscle cell phenotype.
    Wamhoff BR; Lynch KR; Macdonald TL; Owens GK
    Arterioscler Thromb Vasc Biol; 2008 Aug; 28(8):1454-61. PubMed ID: 18535287
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Down-regulation of EDG5/S1P2 during myogenic differentiation results in the specific uncoupling of sphingosine 1-phosphate signalling to phospholipase D.
    Meacci E; Cencetti F; Donati C; Nuti F; Farnararo M; Kohno T; Igarashi Y; Bruni P
    Biochim Biophys Acta; 2003 Sep; 1633(3):133-42. PubMed ID: 14499732
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sphingosine 1-phosphate receptor 3 and RhoA signaling mediate inflammatory gene expression in astrocytes.
    Dusaban SS; Chun J; Rosen H; Purcell NH; Brown JH
    J Neuroinflammation; 2017 Jun; 14(1):111. PubMed ID: 28577576
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biochemical regulation of breast cancer cell expression of S1P2 (Edg-5) and S1P3 (Edg-3) G protein-coupled receptors for sphingosine 1-phosphate.
    Dolezalova H; Shankar G; Huang MC; Bikle DD; Goetzl EJ
    J Cell Biochem; 2003 Mar; 88(4):732-43. PubMed ID: 12577307
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PPARγ agonists upregulate sphingosine 1-phosphate (S1P) receptor 1 expression, which in turn reduces S1P-induced [Ca(2+)]i increases in renal mesangial cells.
    Koch A; Völzke A; Puff B; Blankenbach K; Meyer Zu Heringdorf D; Huwiler A; Pfeilschifter J
    Biochim Biophys Acta; 2013 Nov; 1831(11):1634-43. PubMed ID: 23906789
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sphingosine-1-phosphate receptor-2 mediated NFκB activation contributes to tumor necrosis factor-α induced VCAM-1 and ICAM-1 expression in endothelial cells.
    Zhang W; An J; Jawadi H; Siow DL; Lee JF; Zhao J; Gartung A; Maddipati KR; Honn KV; Wattenberg BW; Lee MJ
    Prostaglandins Other Lipid Mediat; 2013 Oct; 106():62-71. PubMed ID: 23770055
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.