BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 12813054)

  • 1. Chloroquine resistance modulated in vitro by expression levels of the Plasmodium falciparum chloroquine resistance transporter.
    Waller KL; Muhle RA; Ursos LM; Horrocks P; Verdier-Pinard D; Sidhu AB; Fujioka H; Roepe PD; Fidock DA
    J Biol Chem; 2003 Aug; 278(35):33593-601. PubMed ID: 12813054
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Combinatorial Genetic Modeling of pfcrt-Mediated Drug Resistance Evolution in Plasmodium falciparum.
    Gabryszewski SJ; Modchang C; Musset L; Chookajorn T; Fidock DA
    Mol Biol Evol; 2016 Jun; 33(6):1554-70. PubMed ID: 26908582
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance.
    Bray PG; Martin RE; Tilley L; Ward SA; Kirk K; Fidock DA
    Mol Microbiol; 2005 Apr; 56(2):323-33. PubMed ID: 15813727
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chloroquine-resistant isoforms of the Plasmodium falciparum chloroquine resistance transporter acidify lysosomal pH in HEK293 cells more than chloroquine-sensitive isoforms.
    Reeves DC; Liebelt DA; Lakshmanan V; Roepe PD; Fidock DA; Akabas MH
    Mol Biochem Parasitol; 2006 Dec; 150(2):288-99. PubMed ID: 17014918
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A 2-amino quinoline, 5-(3-(2-(7-chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid, interacts with PfMDR1 and inhibits its drug transport in Plasmodium falciparum.
    Edaye S; Reiling SJ; Leimanis ML; Wunderlich J; Rohrbach P; Georges E
    Mol Biochem Parasitol; 2014 Jun; 195(1):34-42. PubMed ID: 24914817
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Drug resistance-associated pfCRT mutations confer decreased Plasmodium falciparum digestive vacuolar pH.
    Bennett TN; Kosar AD; Ursos LM; Dzekunov S; Singh Sidhu AB; Fidock DA; Roepe PD
    Mol Biochem Parasitol; 2004 Jan; 133(1):99-114. PubMed ID: 14668017
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations.
    Sidhu AB; Verdier-Pinard D; Fidock DA
    Science; 2002 Oct; 298(5591):210-3. PubMed ID: 12364805
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural and evolutionary analyses of the Plasmodium falciparum chloroquine resistance transporter.
    Coppée R; Sabbagh A; Clain J
    Sci Rep; 2020 Mar; 10(1):4842. PubMed ID: 32179795
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutations in transmembrane domains 1, 4 and 9 of the Plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine.
    Cooper RA; Lane KD; Deng B; Mu J; Patel JJ; Wellems TE; Su X; Ferdig MT
    Mol Microbiol; 2007 Jan; 63(1):270-82. PubMed ID: 17163969
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance.
    Lakshmanan V; Bray PG; Verdier-Pinard D; Johnson DJ; Horrocks P; Muhle RA; Alakpa GE; Hughes RH; Ward SA; Krogstad DJ; Sidhu AB; Fidock DA
    EMBO J; 2005 Jul; 24(13):2294-305. PubMed ID: 15944738
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Polymorphism in the Plasmodium falciparum chloroquine-resistance transporter protein links verapamil enhancement of chloroquine sensitivity with the clinical efficacy of amodiaquine.
    Warhurst DC
    Malar J; 2003 Sep; 2():31. PubMed ID: 14599295
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Variations in the sequence and expression of the Plasmodium falciparum chloroquine resistance transporter (Pfcrt) and their relationship to chloroquine resistance in vitro.
    Durrand V; Berry A; Sem R; Glaziou P; Beaudou J; Fandeur T
    Mol Biochem Parasitol; 2004 Aug; 136(2):273-85. PubMed ID: 15478806
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Analysis of pfcrt point mutations and chloroquine susceptibility in isolates of Plasmodium falciparum.
    Durand R; Jafari S; Vauzelle J; Delabre JF; Jesic Z; Le Bras J
    Mol Biochem Parasitol; 2001 Apr; 114(1):95-102. PubMed ID: 11356518
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chloroquine resistance-conferring mutations in pfcrt give rise to a chloroquine-associated H+ leak from the malaria parasite's digestive vacuole.
    Lehane AM; Kirk K
    Antimicrob Agents Chemother; 2008 Dec; 52(12):4374-80. PubMed ID: 18852275
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chloroquine transport via the malaria parasite's chloroquine resistance transporter.
    Martin RE; Marchetti RV; Cowan AI; Howitt SM; Bröer S; Kirk K
    Science; 2009 Sep; 325(5948):1680-2. PubMed ID: 19779197
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Multiple drugs compete for transport via the Plasmodium falciparum chloroquine resistance transporter at distinct but interdependent sites.
    Bellanca S; Summers RL; Meyrath M; Dave A; Nash MN; Dittmer M; Sanchez CP; Stein WD; Martin RE; Lanzer M
    J Biol Chem; 2014 Dec; 289(52):36336-51. PubMed ID: 25378409
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Is PfCRT a channel or a carrier? Two competing models explaining chloroquine resistance in Plasmodium falciparum.
    Sanchez CP; Stein WD; Lanzer M
    Trends Parasitol; 2007 Jul; 23(7):332-9. PubMed ID: 17493873
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs.
    Jida M; Sanchez CP; Urgin K; Ehrhardt K; Mounien S; Geyer A; Elhabiri M; Lanzer M; Davioud-Charvet E
    ACS Infect Dis; 2017 Feb; 3(2):119-131. PubMed ID: 28183182
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Verapamil-Sensitive Transport of Quinacrine and Methylene Blue via the Plasmodium falciparum Chloroquine Resistance Transporter Reduces the Parasite's Susceptibility to these Tricyclic Drugs.
    van Schalkwyk DA; Nash MN; Shafik SH; Summers RL; Lehane AM; Smith PJ; Martin RE
    J Infect Dis; 2016 Mar; 213(5):800-10. PubMed ID: 26503982
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional Comparison of 45 Naturally Occurring Isoforms of the Plasmodium falciparum Chloroquine Resistance Transporter (PfCRT).
    Callaghan PS; Hassett MR; Roepe PD
    Biochemistry; 2015 Aug; 54(32):5083-94. PubMed ID: 26208441
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.