186 related articles for article (PubMed ID: 12816949)
1. Facilitated interaction between the pyruvate dehydrogenase kinase isoform 2 and the dihydrolipoyl acetyltransferase.
Hiromasa Y; Roche TE
J Biol Chem; 2003 Sep; 278(36):33681-93. PubMed ID: 12816949
[TBL] [Abstract][Full Text] [Related]
2. Marked differences between two isoforms of human pyruvate dehydrogenase kinase.
Baker JC; Yan X; Peng T; Kasten S; Roche TE
J Biol Chem; 2000 May; 275(21):15773-81. PubMed ID: 10748134
[TBL] [Abstract][Full Text] [Related]
3. Pyruvate dehydrogenase kinase isoform 2 activity limited and further inhibited by slowing down the rate of dissociation of ADP.
Bao H; Kasten SA; Yan X; Roche TE
Biochemistry; 2004 Oct; 43(42):13432-41. PubMed ID: 15491150
[TBL] [Abstract][Full Text] [Related]
4. Pyruvate dehydrogenase kinase isoform 2 activity stimulated by speeding up the rate of dissociation of ADP.
Bao H; Kasten SA; Yan X; Hiromasa Y; Roche TE
Biochemistry; 2004 Oct; 43(42):13442-51. PubMed ID: 15491151
[TBL] [Abstract][Full Text] [Related]
5. Binding of the pyruvate dehydrogenase kinase to recombinant constructs containing the inner lipoyl domain of the dihydrolipoyl acetyltransferase component.
Liu S; Baker JC; Roche TE
J Biol Chem; 1995 Jan; 270(2):793-800. PubMed ID: 7822313
[TBL] [Abstract][Full Text] [Related]
6. Lipoyl domain-based mechanism for the integrated feedback control of the pyruvate dehydrogenase complex by enhancement of pyruvate dehydrogenase kinase activity.
Ravindran S; Radke GA; Guest JR; Roche TE
J Biol Chem; 1996 Jan; 271(2):653-62. PubMed ID: 8557670
[TBL] [Abstract][Full Text] [Related]
7. Partial activation of the pyruvate dehydrogenase kinase by the lipoyl domain region of E2 and interchange of the kinase between lipoyl domain regions.
Ono K; Radke GA; Roche TE; Rahmatullah M
J Biol Chem; 1993 Dec; 268(35):26135-43. PubMed ID: 8253731
[TBL] [Abstract][Full Text] [Related]
8. Reaction mechanism for mammalian pyruvate dehydrogenase using natural lipoyl domain substrates.
Liu S; Gong X; Yan X; Peng T; Baker JC; Li L; Robben PM; Ravindran S; Andersson LA; Cole AB; Roche TE
Arch Biochem Biophys; 2001 Feb; 386(2):123-35. PubMed ID: 11368334
[TBL] [Abstract][Full Text] [Related]
9. Requirements for the adaptor protein role of dihydrolipoyl acetyltransferase in the up-regulated function of the pyruvate dehydrogenase kinase and pyruvate dehydrogenase phosphatase.
Yang D; Gong X; Yakhnin A; Roche TE
J Biol Chem; 1998 Jun; 273(23):14130-7. PubMed ID: 9603912
[TBL] [Abstract][Full Text] [Related]
10. Assembly and full functionality of recombinantly expressed dihydrolipoyl acetyltransferase component of the human pyruvate dehydrogenase complex.
Yang D; Song J; Wagenknecht T; Roche TE
J Biol Chem; 1997 Mar; 272(10):6361-9. PubMed ID: 9045657
[TBL] [Abstract][Full Text] [Related]
11. Activated function of the pyruvate dehydrogenase phosphatase through Ca2+-facilitated binding to the inner lipoyl domain of the dihydrolipoyl acetyltransferase.
Chen G; Wang L; Liu S; Chuang C; Roche TE
J Biol Chem; 1996 Nov; 271(45):28064-70. PubMed ID: 8910418
[TBL] [Abstract][Full Text] [Related]
12. Ligand-induced effects on pyruvate dehydrogenase kinase isoform 2.
Hiromasa Y; Hu L; Roche TE
J Biol Chem; 2006 May; 281(18):12568-79. PubMed ID: 16517984
[TBL] [Abstract][Full Text] [Related]
13. Recombinant expression and evaluation of the lipoyl domains of the dihydrolipoyl acetyltransferase component of the human pyruvate dehydrogenase complex.
Liu S; Baker JC; Andrews PC; Roche TE
Arch Biochem Biophys; 1995 Feb; 316(2):926-40. PubMed ID: 7864652
[TBL] [Abstract][Full Text] [Related]
14. Specific ion influences on self-association of pyruvate dehydrogenase kinase isoform 2 (PDHK2), binding of PDHK2 to the L2 lipoyl domain, and effects of the lipoyl group-binding site inhibitor, Nov3r.
Hiromasa Y; Yan X; Roche TE
Biochemistry; 2008 Feb; 47(8):2312-24. PubMed ID: 18220415
[TBL] [Abstract][Full Text] [Related]
15. Organization of the cores of the mammalian pyruvate dehydrogenase complex formed by E2 and E2 plus the E3-binding protein and their capacities to bind the E1 and E3 components.
Hiromasa Y; Fujisawa T; Aso Y; Roche TE
J Biol Chem; 2004 Feb; 279(8):6921-33. PubMed ID: 14638692
[TBL] [Abstract][Full Text] [Related]
16. Interaction between the individual isoenzymes of pyruvate dehydrogenase kinase and the inner lipoyl-bearing domain of transacetylase component of pyruvate dehydrogenase complex.
Tuganova A; Boulatnikov I; Popov KM
Biochem J; 2002 Aug; 366(Pt 1):129-36. PubMed ID: 11978179
[TBL] [Abstract][Full Text] [Related]
17. Critical role of a lipoyl cofactor of the dihydrolipoyl acetyltransferase in the binding and enhanced function of the pyruvate dehydrogenase kinase.
Radke GA; Ono K; Ravindran S; Roche TE
Biochem Biophys Res Commun; 1993 Feb; 190(3):982-91. PubMed ID: 8439347
[TBL] [Abstract][Full Text] [Related]
18. Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia, and cancer.
Roche TE; Hiromasa Y
Cell Mol Life Sci; 2007 Apr; 64(7-8):830-49. PubMed ID: 17310282
[TBL] [Abstract][Full Text] [Related]
19. R-lipoic acid inhibits mammalian pyruvate dehydrogenase kinase.
Korotchkina LG; Sidhu S; Patel MS
Free Radic Res; 2004 Oct; 38(10):1083-92. PubMed ID: 15512796
[TBL] [Abstract][Full Text] [Related]
20. Nematode pyruvate dehydrogenase kinases: role of the C-terminus in binding to the dihydrolipoyl transacetylase core of the pyruvate dehydrogenase complex.
Chen W; Komuniecki PR; Komuniecki R
Biochem J; 1999 Apr; 339 ( Pt 1)(Pt 1):103-9. PubMed ID: 10085233
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]