BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 12817475)

  • 1. Treatment of tumor cells with histone deacetylase inhibitors results in altered recruitment of methyl-CpG binding proteins to a methylated CpG island.
    Koizume S; Tachibana K; Shiraishi M
    Biol Chem; 2003 May; 384(5):787-90. PubMed ID: 12817475
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells.
    Stirzaker C; Song JZ; Davidson B; Clark SJ
    Cancer Res; 2004 Jun; 64(11):3871-7. PubMed ID: 15172996
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CpG methylation-dependent repression of the human O6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration.
    Bhakat KK; Mitra S
    Carcinogenesis; 2003 Aug; 24(8):1337-45. PubMed ID: 12807730
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cell type-specific methylation of an intronic CpG island controls expression of the MCJ gene.
    Strathdee G; Davies BR; Vass JK; Siddiqui N; Brown R
    Carcinogenesis; 2004 May; 25(5):693-701. PubMed ID: 14729589
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Epigenetic modulation of tumor suppressor CCAAT/enhancer binding protein alpha activity in lung cancer.
    Tada Y; Brena RM; Hackanson B; Morrison C; Otterson GA; Plass C
    J Natl Cancer Inst; 2006 Mar; 98(6):396-406. PubMed ID: 16537832
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Coordinated changes in DNA methylation and histone modifications regulate silencing/derepression of luteinizing hormone receptor gene transcription.
    Zhang Y; Fatima N; Dufau ML
    Mol Cell Biol; 2005 Sep; 25(18):7929-39. PubMed ID: 16135786
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Histone deacetylase inhibitor Trichostatin A induces global and gene-specific DNA demethylation in human cancer cell lines.
    Ou JN; Torrisani J; Unterberger A; Provençal N; Shikimi K; Karimi M; Ekström TJ; Szyf M
    Biochem Pharmacol; 2007 May; 73(9):1297-307. PubMed ID: 17276411
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Heterogeneity in the modification and involvement of chromatin components of the CpG island of the silenced human CDH1 gene in cancer cells.
    Koizume S; Tachibana K; Sekiya T; Hirohashi S; Shiraishi M
    Nucleic Acids Res; 2002 Nov; 30(21):4770-80. PubMed ID: 12409468
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning.
    Hinshelwood RA; Melki JR; Huschtscha LI; Paul C; Song JZ; Stirzaker C; Reddel RR; Clark SJ
    Hum Mol Genet; 2009 Aug; 18(16):3098-109. PubMed ID: 19477956
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transcriptional activation of estrogen receptor alpha in human breast cancer cells by histone deacetylase inhibition.
    Yang X; Ferguson AT; Nass SJ; Phillips DL; Butash KA; Wang SM; Herman JG; Davidson NE
    Cancer Res; 2000 Dec; 60(24):6890-4. PubMed ID: 11156387
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells.
    Konduri SD; Srivenugopal KS; Yanamandra N; Dinh DH; Olivero WC; Gujrati M; Foster DC; Kisiel W; Ali-Osman F; Kondraganti S; Lakka SS; Rao JS
    Oncogene; 2003 Jul; 22(29):4509-16. PubMed ID: 12881707
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Epigenomic changes during leukemia cell differentiation: analysis of histone acetylation and cytosine methylation using CpG island microarrays.
    Nouzova M; Holtan N; Oshiro MM; Isett RB; Munoz-Rodriguez JL; List AF; Narro ML; Miller SJ; Merchant NC; Futscher BW
    J Pharmacol Exp Ther; 2004 Dec; 311(3):968-81. PubMed ID: 15302897
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential distribution of DNA methylation within the RASSF1A CpG island in breast cancer.
    Yan PS; Shi H; Rahmatpanah F; Hsiau TH; Hsiau AH; Leu YW; Liu JC; Huang TH
    Cancer Res; 2003 Oct; 63(19):6178-86. PubMed ID: 14559801
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Uteroplacental insufficiency affects epigenetic determinants of chromatin structure in brains of neonatal and juvenile IUGR rats.
    Ke X; Lei Q; James SJ; Kelleher SL; Melnyk S; Jernigan S; Yu X; Wang L; Callaway CW; Gill G; Chan GM; Albertine KH; McKnight RA; Lane RH
    Physiol Genomics; 2006 Mar; 25(1):16-28. PubMed ID: 16380407
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase (MGMT) gene expression in human cancer.
    Nakagawachi T; Soejima H; Urano T; Zhao W; Higashimoto K; Satoh Y; Matsukura S; Kudo S; Kitajima Y; Harada H; Furukawa K; Matsuzaki H; Emi M; Nakabeppu Y; Miyazaki K; Sekiguchi M; Mukai T
    Oncogene; 2003 Dec; 22(55):8835-44. PubMed ID: 14647440
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cyclin D1 gene activation in human myeloma cells is independent of DNA hypomethylation or histone hyperacetylation.
    Krieger S; Grunau C; Sabbah M; Sola B
    Exp Hematol; 2005 Jun; 33(6):652-9. PubMed ID: 15911089
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer.
    Ballestar E; Paz MF; Valle L; Wei S; Fraga MF; Espada J; Cigudosa JC; Huang TH; Esteller M
    EMBO J; 2003 Dec; 22(23):6335-45. PubMed ID: 14633992
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation.
    Wade PA; Gegonne A; Jones PL; Ballestar E; Aubry F; Wolffe AP
    Nat Genet; 1999 Sep; 23(1):62-6. PubMed ID: 10471500
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Histone acetylation is not an accurate predictor of gene expression following treatment with histone deacetylase inhibitors.
    Ellis DJ; Lawman ZK; Bonham K
    Biochem Biophys Res Commun; 2008 Mar; 367(3):656-62. PubMed ID: 18179771
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Histone modification in the TGFbetaRII gene promoter and its significance for responsiveness to HDAC inhibitor in lung cancer cell lines.
    Osada H; Tatematsu Y; Sugito N; Horio Y; Takahashi T
    Mol Carcinog; 2005 Dec; 44(4):233-41. PubMed ID: 16163707
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.