These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

374 related articles for article (PubMed ID: 12819211)

  • 1. cAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension.
    Christensen AE; Selheim F; de Rooij J; Dremier S; Schwede F; Dao KK; Martinez A; Maenhaut C; Bos JL; Genieser HG; Døskeland SO
    J Biol Chem; 2003 Sep; 278(37):35394-402. PubMed ID: 12819211
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells.
    Roscioni SS; Kistemaker LE; Menzen MH; Elzinga CR; Gosens R; Halayko AJ; Meurs H; Schmidt M
    Respir Res; 2009 Sep; 10(1):88. PubMed ID: 19788733
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3.
    Herfindal L; Krakstad C; Myhren L; Hagland H; Kopperud R; Teigen K; Schwede F; Kleppe R; Døskeland SO
    PLoS One; 2014; 9(4):e94926. PubMed ID: 24740327
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: studies with 8-pCPT-2'-O-Me-cAMP-AM.
    Chepurny OG; Leech CA; Kelley GG; Dzhura I; Dzhura E; Li X; Rindler MJ; Schwede F; Genieser HG; Holz GG
    J Biol Chem; 2009 Apr; 284(16):10728-36. PubMed ID: 19244230
    [TBL] [Abstract][Full Text] [Related]  

  • 5. cAMP effector mechanisms. Novel twists for an 'old' signaling system.
    Kopperud R; Krakstad C; Selheim F; Døskeland SO
    FEBS Lett; 2003 Jul; 546(1):121-6. PubMed ID: 12829247
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Off-target effect of the Epac agonist 8-pCPT-2'-O-Me-cAMP on P2Y12 receptors in blood platelets.
    Herfindal L; Nygaard G; Kopperud R; Krakstad C; Døskeland SO; Selheim F
    Biochem Biophys Res Commun; 2013 Aug; 437(4):603-8. PubMed ID: 23850619
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification and validation of modulators of exchange protein activated by cAMP (Epac) activity: structure-function implications for Epac activation and inhibition.
    Brown LM; Rogers KE; McCammon JA; Insel PA
    J Biol Chem; 2014 Mar; 289(12):8217-30. PubMed ID: 24497631
    [TBL] [Abstract][Full Text] [Related]  

  • 8. cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic beta cells and rat INS-1 cells.
    Kang G; Chepurny OG; Malester B; Rindler MJ; Rehmann H; Bos JL; Schwede F; Coetzee WA; Holz GG
    J Physiol; 2006 Jun; 573(Pt 3):595-609. PubMed ID: 16613879
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors.
    Holz GG; Chepurny OG; Schwede F
    Cell Signal; 2008 Jan; 20(1):10-20. PubMed ID: 17716863
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Epac1 and cAMP-dependent protein kinase holoenzyme have similar cAMP affinity, but their cAMP domains have distinct structural features and cyclic nucleotide recognition.
    Dao KK; Teigen K; Kopperud R; Hodneland E; Schwede F; Christensen AE; Martinez A; Døskeland SO
    J Biol Chem; 2006 Jul; 281(30):21500-21511. PubMed ID: 16728394
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cyclic adenosine 3',5'-monophosphate (cAMP)-dependent protein kinases, but not exchange proteins directly activated by cAMP (Epac), mediate thyrotropin/cAMP-dependent regulation of thyroid cells.
    Dremier S; Milenkovic M; Blancquaert S; Dumont JE; Døskeland SO; Maenhaut C; Roger PP
    Endocrinology; 2007 Oct; 148(10):4612-22. PubMed ID: 17584967
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans.
    Chepurny OG; Kelley GG; Dzhura I; Leech CA; Roe MW; Dzhura E; Li X; Schwede F; Genieser HG; Holz GG
    Am J Physiol Endocrinol Metab; 2010 Mar; 298(3):E622-33. PubMed ID: 20009023
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Influence of cAMP and protein kinase A on neurite length from spiral ganglion neurons.
    Xu N; Engbers J; Khaja S; Xu L; Clark JJ; Hansen MR
    Hear Res; 2012 Jan; 283(1-2):33-44. PubMed ID: 22154930
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1).
    Courilleau D; Bouyssou P; Fischmeister R; Lezoualc'h F; Blondeau JP
    Biochem Biophys Res Commun; 2013 Oct; 440(3):443-8. PubMed ID: 24099776
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential Pharmacophore Definition of the cAMP Binding Sites of Neuritogenic cAMP Sensor-Rapgef2, Protein Kinase A, and Exchange Protein Activated by cAMP in Neuroendocrine Cells Using an Adenine-Based Scaffold.
    Emery AC; Alvarez RA; Eiden MV; Xu W; Siméon FG; Eiden LE
    ACS Chem Neurosci; 2017 Jul; 8(7):1500-1509. PubMed ID: 28290664
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor.
    Rangarajan S; Enserink JM; Kuiperij HB; de Rooij J; Price LS; Schwede F; Bos JL
    J Cell Biol; 2003 Feb; 160(4):487-93. PubMed ID: 12578910
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel Epac fluorescent ligand reveals distinct Epac1 vs. Epac2 distribution and function in cardiomyocytes.
    Pereira L; Rehmann H; Lao DH; Erickson JR; Bossuyt J; Chen J; Bers DM
    Proc Natl Acad Sci U S A; 2015 Mar; 112(13):3991-6. PubMed ID: 25829540
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Epac1 mediates protein kinase A-independent mechanism of forskolin-activated intestinal chloride secretion.
    Hoque KM; Woodward OM; van Rossum DB; Zachos NC; Chen L; Leung GP; Guggino WB; Guggino SE; Tse CM
    J Gen Physiol; 2010 Jan; 135(1):43-58. PubMed ID: 20038525
    [TBL] [Abstract][Full Text] [Related]  

  • 19. cAMP protects neutrophils against TNF-alpha-induced apoptosis by activation of cAMP-dependent protein kinase, independently of exchange protein directly activated by cAMP (Epac).
    Krakstad C; Christensen AE; Døskeland SO
    J Leukoc Biol; 2004 Sep; 76(3):641-7. PubMed ID: 15178699
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of the activation of the Rap-specific exchange factor Epac by cyclic nucleotides.
    Rehmann H
    Methods Enzymol; 2006; 407():159-73. PubMed ID: 16757322
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.