BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

107 related articles for article (PubMed ID: 12821945)

  • 1. p53 mutated in the transactivation domain retains regulatory functions in homology-directed double-strand break repair.
    Boehden GS; Akyüz N; Roemer K; Wiesmüller L
    Oncogene; 2003 Jun; 22(26):4111-7. PubMed ID: 12821945
    [TBL] [Abstract][Full Text] [Related]  

  • 2. p53 in recombination and repair.
    Gatz SA; Wiesmüller L
    Cell Death Differ; 2006 Jun; 13(6):1003-16. PubMed ID: 16543940
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA double-strand break repair activities in mammary epithelial cells--influence of endogenous p53 variants.
    Keimling M; Wiesmüller L
    Carcinogenesis; 2009 Jul; 30(7):1260-8. PubMed ID: 19429664
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel host cell reactivation assay to assess homologous recombination capacity in human cancer cell lines.
    Slebos RJ; Taylor JA
    Biochem Biophys Res Commun; 2001 Feb; 281(1):212-9. PubMed ID: 11178982
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA substrate dependence of p53-mediated regulation of double-strand break repair.
    Akyüz N; Boehden GS; Süsse S; Rimek A; Preuss U; Scheidtmann KH; Wiesmüller L
    Mol Cell Biol; 2002 Sep; 22(17):6306-17. PubMed ID: 12167722
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations.
    Suad O; Rozenberg H; Brosh R; Diskin-Posner Y; Kessler N; Shimon LJ; Frolow F; Liran A; Rotter V; Shakked Z
    J Mol Biol; 2009 Jan; 385(1):249-65. PubMed ID: 18996393
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The neurogene BTG2TIS21/PC3 is transactivated by DeltaNp73alpha via p53 specifically in neuroblastoma cells.
    Goldschneider D; Million K; Meiller A; Haddada H; Puisieux A; Bénard J; May E; Douc-Rasy S
    J Cell Sci; 2005 Mar; 118(Pt 6):1245-53. PubMed ID: 15741235
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Two critical hydrophobic amino acids in the N-terminal domain of the p53 protein are required for the gain of function phenotypes of human p53 mutants.
    Lin J; Teresky AK; Levine AJ
    Oncogene; 1995 Jun; 10(12):2387-90. PubMed ID: 7784087
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome.
    Sigal A; Rotter V
    Cancer Res; 2000 Dec; 60(24):6788-93. PubMed ID: 11156366
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Defective DNA strand break repair after DNA damage in prostate cancer cells: implications for genetic instability and prostate cancer progression.
    Fan R; Kumaravel TS; Jalali F; Marrano P; Squire JA; Bristow RG
    Cancer Res; 2004 Dec; 64(23):8526-33. PubMed ID: 15574758
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hypoxia down-regulates DNA double strand break repair gene expression in prostate cancer cells.
    Meng AX; Jalali F; Cuddihy A; Chan N; Bindra RS; Glazer PM; Bristow RG
    Radiother Oncol; 2005 Aug; 76(2):168-76. PubMed ID: 16026872
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lack of dependence on p53 for DNA double strand break repair of episomal vectors in human lymphoblasts.
    Kohli M; Jorgensen TJ
    Biochem Biophys Res Commun; 1999 Nov; 264(3):702-8. PubMed ID: 10543995
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Physical and functional interactions between members of the tumour suppressor p53 and the Sp families of transcription factors: importance for the regulation of genes involved in cell-cycle arrest and apoptosis.
    Koutsodontis G; Vasilaki E; Chou WC; Papakosta P; Kardassis D
    Biochem J; 2005 Jul; 389(Pt 2):443-55. PubMed ID: 15790310
    [TBL] [Abstract][Full Text] [Related]  

  • 14. p53 directly enhances rejoining of DNA double-strand breaks with cohesive ends in gamma-irradiated mouse fibroblasts.
    Tang W; Willers H; Powell SN
    Cancer Res; 1999 Jun; 59(11):2562-5. PubMed ID: 10363973
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Maintenance of genomic integrity by p53: complementary roles for activated and non-activated p53.
    Albrechtsen N; Dornreiter I; Grosse F; Kim E; Wiesmüller L; Deppert W
    Oncogene; 1999 Dec; 18(53):7706-17. PubMed ID: 10618711
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Analysis of DNA double-strand break repair pathways in mice.
    Brugmans L; Kanaar R; Essers J
    Mutat Res; 2007 Jan; 614(1-2):95-108. PubMed ID: 16797606
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural and functional involvement of p53 in BER in vitro and in vivo.
    Offer H; Milyavsky M; Erez N; Matas D; Zurer I; Harris CC; Rotter V
    Oncogene; 2001 Feb; 20(5):581-9. PubMed ID: 11313990
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The human p53 negative regulatory domain mediates inhibition of reporter gene transactivation in yeast lacking thioredoxin reductase.
    Merrill GF; Dowell P; Pearson GD
    Cancer Res; 1999 Jul; 59(13):3175-9. PubMed ID: 10397262
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hetero-oligomerization does not compromise 'gain of function' of tumor-derived p53 mutants.
    Deb D; Scian M; Roth KE; Li W; Keiger J; Chakraborti AS; Deb SP; Deb S
    Oncogene; 2002 Jan; 21(2):176-89. PubMed ID: 11803461
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deficiencies of double-strand break repair factors and effects on mutagenesis in directly gamma-irradiated and medium-mediated bystander human lymphoblastoid cells.
    Zhang Y; Zhou J; Held KD; Redmond RW; Prise KM; Liber HL
    Radiat Res; 2008 Feb; 169(2):197-206. PubMed ID: 18220473
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.