These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
23. Molecular modeling of the interaction of diagnostic radiopharmaceuticals with receptor proteins: m2 antagonist binding to the muscarinic m2 subtype receptor. Kapp OH; Siemion J; Eckelman WC; Cohen VI; Reba RC Recept Signal Transduct; 1997; 7(3):177-201. PubMed ID: 9440504 [TBL] [Abstract][Full Text] [Related]
24. M2 Subtype preferring dibenzodiazepinone-type muscarinic receptor ligands: Effect of chemical homo-dimerization on orthosteric (and allosteric?) binding. Keller M; Tränkle C; She X; Pegoli A; Bernhardt G; Buschauer A; Read RW Bioorg Med Chem; 2015 Jul; 23(14):3970-90. PubMed ID: 25650309 [TBL] [Abstract][Full Text] [Related]
25. Using a radioalloster to test predictions of the cooperativity model for gallamine binding to the allosteric site of muscarinic acetylcholine M(2) receptors. Tränkle C; Weyand O; Schröter A; Mohr K Mol Pharmacol; 1999 Nov; 56(5):962-5. PubMed ID: 10531401 [TBL] [Abstract][Full Text] [Related]
30. Mutational disruption of a conserved disulfide bond in muscarinic acetylcholine receptors attenuates positive homotropic cooperativity between multiple allosteric sites and has subtype-dependent effects on the affinities of muscarinic allosteric ligands. Huang XP; Ellis J Mol Pharmacol; 2007 Mar; 71(3):759-68. PubMed ID: 17132687 [TBL] [Abstract][Full Text] [Related]
31. Discovery and characterization of orthosteric and allosteric muscarinic M2 acetylcholine receptor ligands by affinity selection-mass spectrometry. Whitehurst CE; Nazef N; Annis DA; Hou Y; Murphy DM; Spacciapoli P; Yao Z; Ziebell MR; Cheng CC; Shipps GW; Felsch JS; Lau D; Nash HM J Biomol Screen; 2006 Mar; 11(2):194-207. PubMed ID: 16490772 [TBL] [Abstract][Full Text] [Related]
32. Modelling of the binding site of the human m1 muscarinic receptor: experimental validation and refinement. Bourdon H; Trumpp-Kallmeyer S; Schreuder H; Hoflack J; Hibert M; Wermuth CG J Comput Aided Mol Des; 1997 Jul; 11(4):317-32. PubMed ID: 9334899 [TBL] [Abstract][Full Text] [Related]
33. Dualsteric muscarinic antagonists--orthosteric binding pose controls allosteric subtype selectivity. Schmitz J; van der Mey D; Bermudez M; Klöckner J; Schrage R; Kostenis E; Tränkle C; Wolber G; Mohr K; Holzgrabe U J Med Chem; 2014 Aug; 57(15):6739-50. PubMed ID: 25051097 [TBL] [Abstract][Full Text] [Related]
34. Three-dimensional models of histamine H3 receptor antagonist complexes and their pharmacophore. Axe FU; Bembenek SD; Szalma S J Mol Graph Model; 2006 May; 24(6):456-64. PubMed ID: 16386444 [TBL] [Abstract][Full Text] [Related]
35. Structure-function studies of allosteric agonism at M2 muscarinic acetylcholine receptors. May LT; Avlani VA; Langmead CJ; Herdon HJ; Wood MD; Sexton PM; Christopoulos A Mol Pharmacol; 2007 Aug; 72(2):463-76. PubMed ID: 17525129 [TBL] [Abstract][Full Text] [Related]
36. Allostery of atypical modulators at oligomeric G protein-coupled receptors. Shivnaraine RV; Kelly B; Elmslie G; Huang XP; Dong YJ; Seidenberg M; Wells JW; Ellis J Sci Rep; 2021 Apr; 11(1):9265. PubMed ID: 33927236 [TBL] [Abstract][Full Text] [Related]
37. Simulations of a G protein-coupled receptor homology model predict dynamic features and a ligand binding site. Wolf S; Böckmann M; Höweler U; Schlitter J; Gerwert K FEBS Lett; 2008 Oct; 582(23-24):3335-42. PubMed ID: 18775703 [TBL] [Abstract][Full Text] [Related]
38. Depolarization induces a conformational change in the binding site region of the M2 muscarinic receptor. Dekel N; Priest MF; Parnas H; Parnas I; Bezanilla F Proc Natl Acad Sci U S A; 2012 Jan; 109(1):285-90. PubMed ID: 22184214 [TBL] [Abstract][Full Text] [Related]
39. In Silico Analysis of Binding Interaction of Mamba Toxins with M4 and M2 Muscarinic Acetylcholine Receptors for Therapeutic Use in Alzheimer's Disease. Waqar M; Kamal MA; Batool S CNS Neurol Disord Drug Targets; 2015; 14(8):1031-40. PubMed ID: 26295818 [TBL] [Abstract][Full Text] [Related]
40. The M1 muscarinic receptor allosteric agonists AC-42 and 1-[1'-(2-methylbenzyl)-1,4'-bipiperidin-4-yl]-1,3-dihydro-2H-benzimidazol-2-one bind to a unique site distinct from the acetylcholine orthosteric site. Jacobson MA; Kreatsoulas C; Pascarella DM; O'Brien JA; Sur C Mol Pharmacol; 2010 Oct; 78(4):648-57. PubMed ID: 20660086 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]