These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 12825928)

  • 21. Discodermolide: just another microtubule-stabilizing agent? No! A lesson in synergy.
    Giannakakou P; Fojo T
    Clin Cancer Res; 2000 May; 6(5):1613-5. PubMed ID: 10815877
    [No Abstract]   [Full Text] [Related]  

  • 22. A quantitative evaluation of the effects of inhibitors of tubulin assembly on polymerization induced by discodermolide, epothilone B, and paclitaxel.
    Dabydeen DA; Florence GJ; Paterson I; Hamel E
    Cancer Chemother Pharmacol; 2004 May; 53(5):397-403. PubMed ID: 15060743
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Design and synthesis of (+)-discodermolide-paclitaxel hybrids leading to enhanced biological activity.
    Smith AB; Sugasawa K; Atasoylu O; Yang CP; Horwitz SB
    J Med Chem; 2011 Sep; 54(18):6319-27. PubMed ID: 21870795
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Toward understanding how the lactone moiety of discodermolide affects activity.
    Shaw SJ; Sundermann KF; Burlingame MA; Myles DC; Freeze BS; Xian M; Brouard I; Smith AB
    J Am Chem Soc; 2005 May; 127(18):6532-3. PubMed ID: 15869264
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Design, synthesis and cytotoxicity of 7-deoxy aryl discodermolide analogues.
    Burlingame MA; Shaw SJ; Sundermann KF; Zhang D; Petryka J; Mendoza E; Liu F; Myles DC; LaMarche MJ; Hirose T; Scott Freeze B; Smith AB
    Bioorg Med Chem Lett; 2004 May; 14(9):2335-8. PubMed ID: 15081036
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Differential effects of natural product microtubule stabilizers on microtubule assembly: single agent and combination studies with taxol, epothilone B, and discodermolide.
    Gertsch J; Meier S; Müller M; Altmann KH
    Chembiochem; 2009 Jan; 10(1):166-75. PubMed ID: 19058273
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Structure-activity relationship studies of discodermolide and its semisynthetic acetylated analogs on microtubule function and cytotoxicity.
    Isbrucker RA; Gunasekera SP; Longley RE
    Cancer Chemother Pharmacol; 2001 Jul; 48(1):29-36. PubMed ID: 11488521
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Distinct pose of discodermolide in taxol binding pocket drives a complementary mode of microtubule stabilization.
    Khrapunovich-Baine M; Menon V; Verdier-Pinard P; Smith AB; Angeletti RH; Fiser A; Horwitz SB; Xiao H
    Biochemistry; 2009 Dec; 48(49):11664-77. PubMed ID: 19863156
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Total synthesis of a potent hybrid of the anticancer natural products dictyostatin and discodermolide.
    Paterson I; Naylor GJ; Wright AE
    Chem Commun (Camb); 2008 Oct; (38):4628-30. PubMed ID: 18815706
    [TBL] [Abstract][Full Text] [Related]  

  • 30. 1,6-asymmetric induction in boron-mediated aldol reactions: application to a practical total synthesis of (+)-discodermolide.
    Paterson I; Delgado O; Florence GJ; Lyothier I; Scott JP; Sereinig N
    Org Lett; 2003 Jan; 5(1):35-8. PubMed ID: 12509884
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Development of practical syntheses of the marine anticancer agents discodermolide and dictyostatin.
    Florence GJ; Gardner NM; Paterson I
    Nat Prod Rep; 2008 Apr; 25(2):342-75. PubMed ID: 18389141
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Acetylated analogues of the microtubule-stabilizing agent discodermolide: preparation and biological activity.
    Gunasekera SP; Longley RE; Isbrucker RA
    J Nat Prod; 2001 Feb; 64(2):171-4. PubMed ID: 11429994
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Suppression of microtubule dynamics by discodermolide by a novel mechanism is associated with mitotic arrest and inhibition of tumor cell proliferation.
    Honore S; Kamath K; Braguer D; Wilson L; Briand C; Jordan MA
    Mol Cancer Ther; 2003 Dec; 2(12):1303-11. PubMed ID: 14707271
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Total synthesis of (+)-discodermolide: a highly convergent fourth-generation approach.
    Smith AB; Freeze BS; Xian M; Hirose T
    Org Lett; 2005 Apr; 7(9):1825-8. PubMed ID: 15844916
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Design, synthesis and biological evaluation of a simplified fluorescently labeled discodermolide as a molecular probe to study the binding of discodermolide to tubulin.
    Qi J; Blanden AR; Bane S; Kingston DG
    Bioorg Med Chem; 2011 Sep; 19(17):5247-54. PubMed ID: 21802957
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Toward a commercial synthesis of (+)-discodermolide.
    Mickel SJ
    Curr Opin Drug Discov Devel; 2004 Nov; 7(6):869-81. PubMed ID: 15595446
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Total synthesis and biological evaluation of a series of macrocyclic hybrids and analogues of the antimitotic natural products dictyostatin, discodermolide, and taxol.
    Paterson I; Naylor GJ; Gardner NM; Guzmán E; Wright AE
    Chem Asian J; 2011 Feb; 6(2):459-73. PubMed ID: 21254424
    [TBL] [Abstract][Full Text] [Related]  

  • 38. [Natural anti-tumor compounds with activity of promoting microtubule assembly].
    Li YZ; Hu W; Zhou L
    Yao Xue Xue Bao; 2001 Feb; 36(2):155-60. PubMed ID: 12579888
    [No Abstract]   [Full Text] [Related]  

  • 39. Formal synthesis of (+)-discodermolide.
    Francavilla C; Chen W; Kinder FR
    Org Lett; 2003 Apr; 5(8):1233-6. PubMed ID: 12688727
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Microtubule interactions with chemically diverse stabilizing agents: thermodynamics of binding to the paclitaxel site predicts cytotoxicity.
    Buey RM; Barasoain I; Jackson E; Meyer A; Giannakakou P; Paterson I; Mooberry S; Andreu JM; Díaz JF
    Chem Biol; 2005 Dec; 12(12):1269-79. PubMed ID: 16356844
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.