BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

367 related articles for article (PubMed ID: 12825932)

  • 1. Structure-activity relationship comparison of (S)-2beta-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes and (R)-2beta-substituted 3beta-(3,4-dichlorophenyl)tropanes at the dopamine transporter.
    Zou MF; Kopajtic T; Katz JL; Newman AH
    J Med Chem; 2003 Jul; 46(14):2908-16. PubMed ID: 12825932
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-activity relationships at monoamine transporters for a series of N-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes: comparative molecular field analysis, synthesis, and pharmacological evaluation.
    Kulkarni SS; Grundt P; Kopajtic T; Katz JL; Newman AH
    J Med Chem; 2004 Jun; 47(13):3388-98. PubMed ID: 15189035
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel N-substituted 3 alpha-[bis(4'-fluorophenyl)methoxy]tropane analogues: selective ligands for the dopamine transporter.
    Agoston GE; Wu JH; Izenwasser S; George C; Katz J; Kline RH; Newman AH
    J Med Chem; 1997 Dec; 40(26):4329-39. PubMed ID: 9435902
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, monoamine transporter binding properties, and behavioral pharmacology of a series of 3beta-(substituted phenyl)-2beta-(3'-substituted isoxazol-5-yl)tropanes.
    Carroll FI; Pawlush N; Kuhar MJ; Pollard GT; Howard JL
    J Med Chem; 2004 Jan; 47(2):296-302. PubMed ID: 14711303
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-activity relationship studies on a novel series of (S)-2beta-substituted 3alpha-[bis(4-fluoro- or 4-chlorophenyl)methoxy]tropane analogues for in vivo investigation.
    Zou MF; Cao J; Kopajtic T; Desai RI; Katz JL; Newman AH
    J Med Chem; 2006 Oct; 49(21):6391-9. PubMed ID: 17034144
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biaryl analogues of conformationally constrained tricyclic tropanes as potent and selective norepinephrine reuptake inhibitors: synthesis and evaluation of their uptake inhibition at monoamine transporter sites.
    Zhou J; Zhang A; Kläss T; Johnson KM; Wang CZ; Ye YP; Kozikowski AP
    J Med Chem; 2003 May; 46(10):1997-2007. PubMed ID: 12723962
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CoMFA study of novel phenyl ring-substituted 3alpha-(diphenylmethoxy)tropane analogues at the dopamine transporter.
    Newman AH; Izenwasser S; Robarge MJ; Kline RH
    J Med Chem; 1999 Sep; 42(18):3502-9. PubMed ID: 10479283
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dual probes for the dopamine transporter and sigma1 receptors: novel piperazinyl alkyl-bis(4'-fluorophenyl)amine analogues as potential cocaine-abuse therapeutic agents.
    Cao J; Kulkarni SS; Husbands SM; Bowen WD; Williams W; Kopajtic T; Katz JL; George C; Newman AH
    J Med Chem; 2003 Jun; 46(13):2589-98. PubMed ID: 12801223
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 3'-Chloro-3 alpha-(diphenylmethoxy)tropane but not 4'-chloro-3 alpha-(diphenylmethoxy)tropane produces a cocaine-like behavioral profile.
    Kline RH; Izenwasser S; Katz JL; Joseph DB; Bowen WD; Newman AH
    J Med Chem; 1997 Mar; 40(6):851-7. PubMed ID: 9083473
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and monoamine transporter binding properties of 2,3-diaryltropanes.
    Kotturi SV; Jiang S; Chang AC; Abraham P; Navarro HA; Kuhar MJ; Carroll FI
    J Med Chem; 2005 Nov; 48(23):7437-44. PubMed ID: 16279803
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and monoamine transporter binding properties of 3beta-(3',4'-disubstituted phenyl)tropane-2beta-carboxylic acid methyl esters.
    Carroll FI; Blough BE; Nie Z; Kuhar MJ; Howell LL; Navarro HA
    J Med Chem; 2005 Apr; 48(8):2767-71. PubMed ID: 15828814
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Highly selective chiral N-substituted 3alpha-[bis(4'-fluorophenyl)methoxy]tropane analogues for the dopamine transporter: synthesis and comparative molecular field analysis.
    Robarge MJ; Agoston GE; Izenwasser S; Kopajtic T; George C; Katz JL; Newman AH
    J Med Chem; 2000 Mar; 43(6):1085-93. PubMed ID: 10737741
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and monoamine transporter binding of 2-(diarylmethoxymethyl)-3 beta-aryltropane derivatives.
    Xu L; Kulkarni SS; Izenwasser S; Katz JL; Kopajtic T; Lomenzo SA; Newman AH; Trudell ML
    J Med Chem; 2004 Mar; 47(7):1676-82. PubMed ID: 15027858
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel tropane-based irreversible ligands for the dopamine transporter.
    Zou MF; Kopajtic T; Katz JL; Wirtz S; Justice JB; Newman AH
    J Med Chem; 2001 Dec; 44(25):4453-61. PubMed ID: 11728190
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, radiosynthesis, and biological evaluation of carbon-11 and iodine-123 labeled 2beta-carbomethoxy-3beta-[4'-((Z)-2-haloethenyl)phenyl]tropanes: candidate radioligands for in vivo imaging of the serotonin transporter.
    Plisson C; McConathy J; Martarello L; Malveaux EJ; Camp VM; Williams L; Votaw JR; Goodman MM
    J Med Chem; 2004 Feb; 47(5):1122-35. PubMed ID: 14971892
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of N-substituted analogs of benztropine: diminished cocaine-like effects in dopamine transporter ligands.
    Katz JL; Kopajtic TA; Agoston GE; Newman AH
    J Pharmacol Exp Ther; 2004 May; 309(2):650-60. PubMed ID: 14755006
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chemistry and pharmacology of the piperidine-based analogues of cocaine. Identification of potent DAT inhibitors lacking the tropane skeleton.
    Kozikowski AP; Araldi GL; Boja J; Meil WM; Johnson KM; Flippen-Anderson JL; George C; Saiah E
    J Med Chem; 1998 May; 41(11):1962-9. PubMed ID: 9599245
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-activity relationships at monoamine transporters and muscarinic receptors for N-substituted-3alpha-(3'-chloro-, 4'-chloro-, and 4',4''-dichloro-substituted-diphenyl)methoxytropanes.
    Newman AH; Robarge MJ; Howard IM; Wittkopp SL; George C; Kopajtic T; Izenwasser S; Katz JL
    J Med Chem; 2001 Feb; 44(4):633-40. PubMed ID: 11170654
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and pharmacology of 6-substituted benztropines: discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter.
    Simoni D; Rossi M; Bertolasi V; Roberti M; Pizzirani D; Rondanin R; Baruchello R; Invidiata FP; Tolomeo M; Grimaudo S; Merighi S; Varani K; Gessi S; Borea PA; Marino S; Cavallini S; Bianchi C; Siniscalchi A
    J Med Chem; 2005 May; 48(9):3337-43. PubMed ID: 15857139
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, structure, dopamine transporter affinity, and dopamine uptake inhibition of 6-alkyl-3-benzyl-2-[(methoxycarbonyl)methyl]tropane derivatives.
    Lomenzo SA; Izenwasser S; Katz JL; Terry PD; Zhu N; Klein CL; Trudell ML
    J Med Chem; 1997 Dec; 40(26):4406-14. PubMed ID: 9435910
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.