403 related articles for article (PubMed ID: 12832479)
1. Critical contribution of the MDM2 acidic domain to p53 ubiquitination.
Kawai H; Wiederschain D; Yuan ZM
Mol Cell Biol; 2003 Jul; 23(14):4939-47. PubMed ID: 12832479
[TBL] [Abstract][Full Text] [Related]
2. Overexpression of Mdm2 and MdmX fusion proteins alters p53 mediated transactivation, ubiquitination, and degradation.
Ghosh M; Huang K; Berberich SJ
Biochemistry; 2003 Mar; 42(8):2291-9. PubMed ID: 12600196
[TBL] [Abstract][Full Text] [Related]
3. Critical role for a central part of Mdm2 in the ubiquitylation of p53.
Meulmeester E; Frenk R; Stad R; de Graaf P; Marine JC; Vousden KH; Jochemsen AG
Mol Cell Biol; 2003 Jul; 23(14):4929-38. PubMed ID: 12832478
[TBL] [Abstract][Full Text] [Related]
4. A site-directed mutagenesis study of the MdmX RING domain.
Egorova O; Mis M; Sheng Y
Biochem Biophys Res Commun; 2014 May; 447(4):696-701. PubMed ID: 24755078
[TBL] [Abstract][Full Text] [Related]
5. MdmX is a RING finger ubiquitin ligase capable of synergistically enhancing Mdm2 ubiquitination.
Badciong JC; Haas AL
J Biol Chem; 2002 Dec; 277(51):49668-75. PubMed ID: 12393902
[TBL] [Abstract][Full Text] [Related]
6. p53 regulation: teamwork between RING domains of Mdm2 and MdmX.
Wang X
Cell Cycle; 2011 Dec; 10(24):4225-9. PubMed ID: 22134240
[TBL] [Abstract][Full Text] [Related]
7. MDMX is essential for the regulation of p53 protein levels in the absence of a functional MDM2 C-terminal tail.
Sanford JD; Yang J; Han J; Tollini LA; Jin A; Zhang Y
BMC Mol Cell Biol; 2021 Sep; 22(1):46. PubMed ID: 34551723
[TBL] [Abstract][Full Text] [Related]
8. MDMX Recruits UbcH5c to Facilitate MDM2 E3 Ligase Activity and Subsequent p53 Degradation
Yang J; Jin A; Han J; Chen X; Zheng J; Zhang Y
Cancer Res; 2021 Feb; 81(4):898-909. PubMed ID: 33277368
[TBL] [Abstract][Full Text] [Related]
9. Inactivation of the MDM2 RING domain enhances p53 transcriptional activity in mice.
Tian H; Tackmann NR; Jin A; Zheng J; Zhang Y
J Biol Chem; 2017 Dec; 292(52):21614-21622. PubMed ID: 29123033
[TBL] [Abstract][Full Text] [Related]
10. Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms.
Stad R; Little NA; Xirodimas DP; Frenk R; van der Eb AJ; Lane DP; Saville MK; Jochemsen AG
EMBO Rep; 2001 Nov; 2(11):1029-34. PubMed ID: 11606419
[TBL] [Abstract][Full Text] [Related]
11. MDM2 promotes ubiquitination and degradation of MDMX.
Pan Y; Chen J
Mol Cell Biol; 2003 Aug; 23(15):5113-21. PubMed ID: 12860999
[TBL] [Abstract][Full Text] [Related]
12. The MDM2 RING domain and central acidic domain play distinct roles in MDM2 protein homodimerization and MDM2-MDMX protein heterodimerization.
Leslie PL; Ke H; Zhang Y
J Biol Chem; 2015 May; 290(20):12941-50. PubMed ID: 25809483
[TBL] [Abstract][Full Text] [Related]
13. MdmX protein is essential for Mdm2 protein-mediated p53 polyubiquitination.
Wang X; Wang J; Jiang X
J Biol Chem; 2011 Jul; 286(27):23725-34. PubMed ID: 21572037
[TBL] [Abstract][Full Text] [Related]
14. Mdm2 and MdmX RING Domains Play Distinct Roles in the Regulation of p53 Responses: A Comparative Study of Mdm2 and MdmX RING Domains in U2OS Cells.
Egorova O; Lau HH; McGraphery K; Sheng Y
Int J Mol Sci; 2020 Feb; 21(4):. PubMed ID: 32075226
[TBL] [Abstract][Full Text] [Related]
15. Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase.
Okamoto K; Taya Y; Nakagama H
FEBS Lett; 2009 Sep; 583(17):2710-4. PubMed ID: 19619542
[TBL] [Abstract][Full Text] [Related]
16. The contribution of the acidic domain of MDM2 to p53 and MDM2 stability.
Argentini M; Barboule N; Wasylyk B
Oncogene; 2001 Mar; 20(11):1267-75. PubMed ID: 11313871
[TBL] [Abstract][Full Text] [Related]
17. Interplay between MDM2, MDMX, Pirh2 and COP1: the negative regulators of p53.
Wang L; He G; Zhang P; Wang X; Jiang M; Yu L
Mol Biol Rep; 2011 Jan; 38(1):229-36. PubMed ID: 20333547
[TBL] [Abstract][Full Text] [Related]
18. Mutant p53 Sequestration of the MDM2 Acidic Domain Inhibits E3 Ligase Activity.
Yang L; Song T; Cheng Q; Chen L; Chen J
Mol Cell Biol; 2019 Feb; 39(4):. PubMed ID: 30455251
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of p53 degradation by Mdm2 acetylation.
Wang X; Taplick J; Geva N; Oren M
FEBS Lett; 2004 Mar; 561(1-3):195-201. PubMed ID: 15013777
[TBL] [Abstract][Full Text] [Related]
20. Auto-ubiquitination of Mdm2 enhances its substrate ubiquitin ligase activity.
Ranaweera RS; Yang X
J Biol Chem; 2013 Jun; 288(26):18939-46. PubMed ID: 23671280
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]