143 related articles for article (PubMed ID: 12835482)
1. Bruton's tyrosine kinase cooperates with the B cell linker protein SLP-65 as a tumor suppressor in Pre-B cells.
Kersseboom R; Middendorp S; Dingjan GM; Dahlenborg K; Reth M; Jumaa H; Hendriks RW
J Exp Med; 2003 Jul; 198(1):91-8. PubMed ID: 12835482
[TBL] [Abstract][Full Text] [Related]
2. Involvement of SLP-65 and Btk in tumor suppression and malignant transformation of pre-B cells.
Hendriks RW; Kersseboom R
Semin Immunol; 2006 Feb; 18(1):67-76. PubMed ID: 16300960
[TBL] [Abstract][Full Text] [Related]
3. The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion.
Flemming A; Brummer T; Reth M; Jumaa H
Nat Immunol; 2003 Jan; 4(1):38-43. PubMed ID: 12436112
[TBL] [Abstract][Full Text] [Related]
4. Bruton's tyrosine kinase and SLP-65 regulate pre-B cell differentiation and the induction of Ig light chain gene rearrangement.
Kersseboom R; Ta VB; Zijlstra AJ; Middendorp S; Jumaa H; van Loo PF; Hendriks RW
J Immunol; 2006 Apr; 176(8):4543-52. PubMed ID: 16585544
[TBL] [Abstract][Full Text] [Related]
5. Deficiency of the adaptor SLP-65 in pre-B-cell acute lymphoblastic leukaemia.
Jumaa H; Bossaller L; Portugal K; Storch B; Lotz M; Flemming A; Schrappe M; Postila V; Riikonen P; Pelkonen J; Niemeyer CM; Reth M
Nature; 2003 May; 423(6938):452-6. PubMed ID: 12761551
[TBL] [Abstract][Full Text] [Related]
6. Pre-B-cell leukemias in Btk/Slp65-deficient mice arise independently of ongoing V(D)J recombination activity.
Ta VB; de Haan AB; de Bruijn MJ; Dingjan GM; Hendriks RW
Leukemia; 2011 Jan; 25(1):48-56. PubMed ID: 21030983
[TBL] [Abstract][Full Text] [Related]
7. Tumor suppressor function of Bruton tyrosine kinase is independent of its catalytic activity.
Middendorp S; Zijlstra AJ; Kersseboom R; Dingjan GM; Jumaa H; Hendriks RW
Blood; 2005 Jan; 105(1):259-65. PubMed ID: 15331445
[TBL] [Abstract][Full Text] [Related]
8. Deficiency of Bruton's tyrosine kinase in B cell precursor leukemia cells.
Feldhahn N; Río P; Soh BN; Liedtke S; Sprangers M; Klein F; Wernet P; Jumaa H; Hofmann WK; Hanenberg H; Rowley JD; Müschen M
Proc Natl Acad Sci U S A; 2005 Sep; 102(37):13266-71. PubMed ID: 16141323
[TBL] [Abstract][Full Text] [Related]
9. Dual role of the adaptor protein SLP-65: organizer of signal transduction and tumor suppressor of pre-B cell leukemia.
Herzog S; Storch B; Jumaa H
Immunol Res; 2006; 34(2):143-55. PubMed ID: 16760574
[TBL] [Abstract][Full Text] [Related]
10. Btk and phospholipase C gamma 2 can function independently during B cell development.
Halcomb KE; Contreras CM; Hinman RM; Coursey TG; Wright HL; Satterthwaite AB
Eur J Immunol; 2007 Apr; 37(4):1033-42. PubMed ID: 17372989
[TBL] [Abstract][Full Text] [Related]
11. Constitutive activation of Bruton's tyrosine kinase induces the formation of autoreactive IgM plasma cells.
Kersseboom R; Kil L; Flierman R; van der Zee M; Dingjan GM; Middendorp S; Maas A; Hendriks RW
Eur J Immunol; 2010 Sep; 40(9):2643-54. PubMed ID: 20623551
[TBL] [Abstract][Full Text] [Related]
12. Severe B cell deficiency and disrupted splenic architecture in transgenic mice expressing the E41K mutated form of Bruton's tyrosine kinase.
Dingjan GM; Maas A; Nawijn MC; Smit L; Voerman JS; Grosveld F; Hendriks RW
EMBO J; 1998 Sep; 17(18):5309-20. PubMed ID: 9736610
[TBL] [Abstract][Full Text] [Related]
13. The B cell-restricted adaptor BASH is required for normal development and antigen receptor-mediated activation of B cells.
Hayashi K; Nittono R; Okamoto N; Tsuji S; Hara Y; Goitsuka R; Kitamura D
Proc Natl Acad Sci U S A; 2000 Mar; 97(6):2755-60. PubMed ID: 10688901
[TBL] [Abstract][Full Text] [Related]
14. Early arrest in B cell development in transgenic mice that express the E41K Bruton's tyrosine kinase mutant under the control of the CD19 promoter region.
Maas A; Dingjan GM; Grosveld F; Hendriks RW
J Immunol; 1999 Jun; 162(11):6526-33. PubMed ID: 10352268
[TBL] [Abstract][Full Text] [Related]
15. Function of Bruton's tyrosine kinase during B cell development is partially independent of its catalytic activity.
Middendorp S; Dingjan GM; Maas A; Dahlenborg K; Hendriks RW
J Immunol; 2003 Dec; 171(11):5988-96. PubMed ID: 14634110
[TBL] [Abstract][Full Text] [Related]
16. Bruton's tyrosine kinase prevents activation of the anti-apoptotic transcription factor STAT3 and promotes apoptosis in neoplastic B-cells and B-cell precursors exposed to oxidative stress.
Uckun F; Ozer Z; Vassilev A
Br J Haematol; 2007 Feb; 136(4):574-89. PubMed ID: 17367410
[TBL] [Abstract][Full Text] [Related]
17. The pre-BCR checkpoint as a cell-autonomous proliferation switch.
Hendriks RW; Middendorp S
Trends Immunol; 2004 May; 25(5):249-56. PubMed ID: 15099565
[No Abstract] [Full Text] [Related]
18. The Bruton's tyrosine kinase gene is expressed throughout B cell differentiation, from early precursor B cell stages preceding immunoglobulin gene rearrangement up to mature B cell stages.
de Weers M; Verschuren MC; Kraakman ME; Mensink RG; Schuurman RK; van Dongen JJ; Hendriks RW
Eur J Immunol; 1993 Dec; 23(12):3109-14. PubMed ID: 8258324
[TBL] [Abstract][Full Text] [Related]
19. Inactivation of Btk by insertion of lacZ reveals defects in B cell development only past the pre-B cell stage.
Hendriks RW; de Bruijn MF; Maas A; Dingjan GM; Karis A; Grosveld F
EMBO J; 1996 Sep; 15(18):4862-72. PubMed ID: 8890160
[TBL] [Abstract][Full Text] [Related]
20. The BCR-ABL1 kinase bypasses selection for the expression of a pre-B cell receptor in pre-B acute lymphoblastic leukemia cells.
Klein F; Feldhahn N; Harder L; Wang H; Wartenberg M; Hofmann WK; Wernet P; Siebert R; Müschen M
J Exp Med; 2004 Mar; 199(5):673-85. PubMed ID: 14993251
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]