296 related articles for article (PubMed ID: 12837490)
1. Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically exerts cytotoxicity towards human malignant cell lines.
Hostanska K; Reichling J; Bommer S; Weber M; Saller R
Eur J Pharm Biopharm; 2003 Jul; 56(1):121-32. PubMed ID: 12837490
[TBL] [Abstract][Full Text] [Related]
2. Aqueous ethanolic extract of St. John's wort (Hypericum perforatum L.) induces growth inhibition and apoptosis in human malignant cells in vitro.
Hostanska K; Reichling J; Bommer S; Weber M; Saller R
Pharmazie; 2002 May; 57(5):323-31. PubMed ID: 12061257
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis.
Schempp CM; Kirkin V; Simon-Haarhaus B; Kersten A; Kiss J; Termeer CC; Gilb B; Kaufmann T; Borner C; Sleeman JP; Simon JC
Oncogene; 2002 Feb; 21(8):1242-50. PubMed ID: 11850844
[TBL] [Abstract][Full Text] [Related]
4. Protective effects of St. John's wort extract and its component hyperforin against cytokine-induced cytotoxicity in a pancreatic beta-cell line.
Menegazzi M; Novelli M; Beffy P; D'Aleo V; Tedeschi E; Lupi R; Zoratti E; Marchetti P; Suzuki H; Masiello P
Int J Biochem Cell Biol; 2008; 40(8):1509-21. PubMed ID: 18226577
[TBL] [Abstract][Full Text] [Related]
5. Functional induction and de-induction of P-glycoprotein by St. John's wort and its ingredients in a human colon adenocarcinoma cell line.
Tian R; Koyabu N; Morimoto S; Shoyama Y; Ohtani H; Sawada Y
Drug Metab Dispos; 2005 Apr; 33(4):547-54. PubMed ID: 15640377
[TBL] [Abstract][Full Text] [Related]
6. [Hypericin and hyperforin: bioactive components of St. John's Wort (Hypericum perforatum). Their isolation, analysis and study of physiological effect].
Vacek J; Klejdus B; Kubán V
Ceska Slov Farm; 2007 Apr; 56(2):62-6. PubMed ID: 17619301
[TBL] [Abstract][Full Text] [Related]
7. Effect of St. John's wort on free radical production.
Hunt EJ; Lester CE; Lester EA; Tackett RL
Life Sci; 2001 Jun; 69(2):181-90. PubMed ID: 11441908
[TBL] [Abstract][Full Text] [Related]
8. In vitro binding studies with two hypericum perforatum extracts--hyperforin, hypericin and biapigenin--on 5-HT6, 5-HT7, GABA(A)/benzodiazepine, sigma, NPY-Y1/Y2 receptors and dopamine transporters.
Gobbi M; Moia M; Pirona L; Morizzoni P; Mennini T
Pharmacopsychiatry; 2001 Jul; 34 Suppl 1():S45-8. PubMed ID: 11518075
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of human cytochrome P450 enzymes by constituents of St. John's Wort, an herbal preparation used in the treatment of depression.
Obach RS
J Pharmacol Exp Ther; 2000 Jul; 294(1):88-95. PubMed ID: 10871299
[TBL] [Abstract][Full Text] [Related]
10. Quantitative characterization of direct P-glycoprotein inhibition by St John's wort constituents hypericin and hyperforin.
Wang EJ; Barecki-Roach M; Johnson WW
J Pharm Pharmacol; 2004 Jan; 56(1):123-8. PubMed ID: 14980009
[TBL] [Abstract][Full Text] [Related]
11. The main components of St John's Wort inhibit low-density lipoprotein atherogenic modification: a beneficial "side effect" of an OTC antidepressant drug?
Laggner H; Schreier S; Hermann M; Exner M; Mühl A; Gmeiner BM; Kapiotis S
Free Radic Res; 2007 Feb; 41(2):234-41. PubMed ID: 17364950
[TBL] [Abstract][Full Text] [Related]
12. Simultaneous determination of total hypericin and hyperforin in St. John's wort extracts by HPLC with electrochemical detection.
Rückert U; Likussar W; Michelitsch A
Phytochem Anal; 2007; 18(3):204-8. PubMed ID: 17500362
[TBL] [Abstract][Full Text] [Related]
13. Pharmacological and endocrine effects of Hypericum perforatum and hypericin after repeated treatment.
Butterweck V; Korte B; Winterhoff H
Pharmacopsychiatry; 2001 Jul; 34 Suppl 1():S2-7. PubMed ID: 11518068
[TBL] [Abstract][Full Text] [Related]
14. Step by step removal of hyperforin and hypericin: activity profile of different Hypericum preparations in behavioral models.
Butterweck V; Christoffel V; Nahrstedt A; Petereit F; Spengler B; Winterhoff H
Life Sci; 2003 Jun; 73(5):627-39. PubMed ID: 12770617
[TBL] [Abstract][Full Text] [Related]
15. St. John's wort: role of active compounds for its mechanism of action and efficacy.
Butterweck V; Schmidt M
Wien Med Wochenschr; 2007; 157(13-14):356-61. PubMed ID: 17704987
[TBL] [Abstract][Full Text] [Related]
16. The pro-apoptotic and anti-invasive effects of hypericin-mediated photodynamic therapy are enhanced by hyperforin or aristoforin in HT-29 colon adenocarcinoma cells.
Šemeláková M; Mikeš J; Jendželovský R; Fedoročko P
J Photochem Photobiol B; 2012 Dec; 117():115-25. PubMed ID: 23099482
[TBL] [Abstract][Full Text] [Related]
17. Topical application of St John's wort (Hypericum perforatum L.) and of its metabolite hyperforin inhibits the allostimulatory capacity of epidermal cells.
Schempp CM; Winghofer B; Lüdtke R; Simon-Haarhaus B; Schöpf E; Simon JC
Br J Dermatol; 2000 May; 142(5):979-84. PubMed ID: 10809859
[TBL] [Abstract][Full Text] [Related]
18. Researching the antidepressant actions of Hypericum perforatum (St. John's wort) in animals and man.
Franklin M; Cowen PJ
Pharmacopsychiatry; 2001 Jul; 34 Suppl 1():S29-37. PubMed ID: 11518072
[TBL] [Abstract][Full Text] [Related]
19. Understanding drug interactions with St John's wort (Hypericum perforatum L.): impact of hyperforin content.
Chrubasik-Hausmann S; Vlachojannis J; McLachlan AJ
J Pharm Pharmacol; 2019 Jan; 71(1):129-138. PubMed ID: 29411879
[TBL] [Abstract][Full Text] [Related]
20. Involvement of serotoninergic 5-HT1A/2A, alpha-adrenergic and dopaminergic D1 receptors in St. John's wort-induced prepulse inhibition deficit: a possible role of hyperforin.
Tadros MG; Mohamed MR; Youssef AM; Sabry GM; Sabry NA; Khalifa AE
Behav Brain Res; 2009 May; 199(2):334-9. PubMed ID: 19136030
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
