These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

379 related articles for article (PubMed ID: 1283905)

  • 1. Substitution of non-catalytic stem and loop regions of hammerhead ribozyme with DNA counterparts only increases KM without sacrificing the catalytic step (kcat): a way to improve substrate-specificity.
    Shimayama T; Sawata S; Komiyama M; Takagi Y; Tanaka Y; Wada A; Sugimoto N; Rossi JJ; Nishikawa F; Nishikawa S
    Nucleic Acids Symp Ser; 1992; (27):17-8. PubMed ID: 1283905
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nuclease-resistant chimeric ribozymes containing deoxyribonucleotides and phosphorothioate linkages.
    Shimayama T; Nishikawa F; Nishikawa S; Taira K
    Nucleic Acids Res; 1993 Jun; 21(11):2605-11. PubMed ID: 8332458
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acquisition of novel catalytic activity by the M1 RNA ribozyme: the cost of molecular adaptation.
    Cole KB; Dorit RL
    J Mol Biol; 1999 Oct; 292(4):931-44. PubMed ID: 10525416
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The effect of universal fluorinated nucleobases on the catalytic activity of ribozymes.
    Klöpffer AE; Engels JW
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):1347-50. PubMed ID: 14565415
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparative single-turnover kinetic analyses of trans-cleaving hammerhead ribozymes with naturally derived non-conserved sequence motifs.
    Weinberg MS; Rossi JJ
    FEBS Lett; 2005 Mar; 579(7):1619-24. PubMed ID: 15757651
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Importance of specific purine-pyrimidine amino and hydroxyl groups for efficient cleavage by a hammerhead ribozyme.
    Tanaka H; Hosaka H; Takahashi R; Imamura Y; Takai K; Yokoyama S; Takaku H
    Nucleic Acids Symp Ser; 1993; (29):175-6. PubMed ID: 8247757
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enhancement of the cleavage rates of DNA-armed hammerhead ribozymes by various divalent metal ions.
    Sawata S; Shimayama T; Komiyama M; Kumar PK; Nishikawa S; Taira K
    Nucleic Acids Res; 1993 Dec; 21(24):5656-60. PubMed ID: 7506830
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Isolation of active ribozymes from an RNA pool of random sequences using an anchored substrate RNA.
    Ishizaka M; Ohshima Y; Tani T
    Biochem Biophys Res Commun; 1995 Sep; 214(2):403-9. PubMed ID: 7545903
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Construction of new ribozymes requiring short regulator oligonucleotides as a cofactor.
    Komatsu Y; Yamashita S; Kazama N; Nobuoka K; Ohtsuka E
    J Mol Biol; 2000 Jun; 299(5):1231-43. PubMed ID: 10873448
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of deoxyribonucleotide substitutions in the substrate strand on hammerhead ribozyme-catalyzed reactions.
    Shimayama T
    Gene; 1994 Nov; 149(1):41-6. PubMed ID: 7525411
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Determination of hammerhead ribozyme kinetic constants at high molar ratio ribozyme-substrate.
    Grassi G; Grassi M; Kuhn A; Kandolf R
    J Math Biol; 2002 Sep; 45(3):261-77. PubMed ID: 12373347
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HIV-1 TAR as anchoring site for optimized catalytic RNAs.
    Puerta-Fernandez E; Barroso-del Jesus A; Romero-López C; Berzal-Herranz A
    Biol Chem; 2003 Mar; 384(3):343-50. PubMed ID: 12715885
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Efficient improvement of hammerhead ribozyme mediated cleavage of long substrates by oligonucleotide facilitators.
    Jankowsky E; Schwenzer B
    Biochemistry; 1996 Dec; 35(48):15313-21. PubMed ID: 8952482
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparison of activities between hammerhead ribozymes and DNA enzymes targeted to L6 BCR-ABL chimeric (b2a2) mRNA.
    Warashina M; Kuwabara T; Taira K
    Nucleic Acids Symp Ser; 1997; (37):213-4. PubMed ID: 9586075
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RNA-RNA and RNA-DNA ligation with the sTobRV(+) hammerhead ribozyme.
    Tokumoto Y; Saigo K
    Nucleic Acids Symp Ser; 1992; (27):21-2. PubMed ID: 1283908
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Diffusely bound Mg2+ ions slightly reorient stems I and II of the hammerhead ribozyme to increase the probability of formation of the catalytic core.
    Rueda D; Wick K; McDowell SE; Walter NG
    Biochemistry; 2003 Aug; 42(33):9924-36. PubMed ID: 12924941
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of 2'-aminoalkyl-substituted fluorinated nucleobases and their influence on the kinetic properties of hammerhead ribozymes.
    Klöpffer AE; Engels JW
    Chembiochem; 2004 May; 5(5):707-16. PubMed ID: 15122643
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mixed deoxyribo- and ribo-oligonucleotides with catalytic activity.
    Perreault JP; Wu TF; Cousineau B; Ogilvie KK; Cedergren R
    Nature; 1990 Apr; 344(6266):565-7. PubMed ID: 2181322
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The mechanism of the hammerhead ribozyme.
    Hendry P; McCall MJ; Lockett TJ
    Nucleic Acids Symp Ser; 1995; (34):217-8. PubMed ID: 8841629
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chimeric DNA-RNA hammerhead ribozymes have enhanced in vitro catalytic efficiency and increased stability in vivo.
    Taylor NR; Kaplan BE; Swiderski P; Li H; Rossi JJ
    Nucleic Acids Res; 1992 Sep; 20(17):4559-65. PubMed ID: 1408757
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.