BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

371 related articles for article (PubMed ID: 12842910)

  • 1. cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.
    Jhala US; Canettieri G; Screaton RA; Kulkarni RN; Krajewski S; Reed J; Walker J; Lin X; White M; Montminy M
    Genes Dev; 2003 Jul; 17(13):1575-80. PubMed ID: 12842910
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function.
    Park S; Dong X; Fisher TL; Dunn S; Omer AK; Weir G; White MF
    J Biol Chem; 2006 Jan; 281(2):1159-68. PubMed ID: 16272563
    [TBL] [Abstract][Full Text] [Related]  

  • 3. GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.
    Annerén C; Welsh M
    Mol Med; 2002 Nov; 8(11):705-13. PubMed ID: 12520087
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Calcineurin signaling regulates human islet {beta}-cell survival.
    Soleimanpour SA; Crutchlow MF; Ferrari AM; Raum JC; Groff DN; Rankin MM; Liu C; De León DD; Naji A; Kushner JA; Stoffers DA
    J Biol Chem; 2010 Dec; 285(51):40050-9. PubMed ID: 20943662
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein.
    Mehrhof FB; Müller FU; Bergmann MW; Li P; Wang Y; Schmitz W; Dietz R; von Harsdorf R
    Circulation; 2001 Oct; 104(17):2088-94. PubMed ID: 11673351
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins.
    Welsh N; Makeeva N; Welsh M
    Mol Med; 2002 Nov; 8(11):695-704. PubMed ID: 12520086
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of phosphatidylinositol 3-kinase contributes to insulin-like growth factor I-mediated inhibition of pancreatic beta-cell death.
    Liu W; Chin-Chance C; Lee EJ; Lowe WL
    Endocrinology; 2002 Oct; 143(10):3802-12. PubMed ID: 12239091
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glucagon promotes cAMP-response element-binding protein phosphorylation via activation of ERK1/2 in MIN6 cell line and isolated islets of Langerhans.
    Dalle S; Longuet C; Costes S; Broca C; Faruque O; Fontés G; Hani EH; Bataille D
    J Biol Chem; 2004 May; 279(19):20345-55. PubMed ID: 14988413
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transfection of pancreatic-derived beta-cells with a minigene encoding for human glucagon-like peptide-1 regulates glucose-dependent insulin synthesis and secretion.
    Hui H; Yu R; Bousquet C; Perfetti R
    Endocrinology; 2002 Sep; 143(9):3529-39. PubMed ID: 12193567
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling.
    Canettieri G; Koo SH; Berdeaux R; Heredia J; Hedrick S; Zhang X; Montminy M
    Cell Metab; 2005 Nov; 2(5):331-8. PubMed ID: 16271533
    [TBL] [Abstract][Full Text] [Related]  

  • 11. mTOR links incretin signaling to HIF induction in pancreatic beta cells.
    Van de Velde S; Hogan MF; Montminy M
    Proc Natl Acad Sci U S A; 2011 Oct; 108(41):16876-82. PubMed ID: 21949366
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Small molecule kaempferol modulates PDX-1 protein expression and subsequently promotes pancreatic β-cell survival and function via CREB.
    Zhang Y; Zhen W; Maechler P; Liu D
    J Nutr Biochem; 2013 Apr; 24(4):638-46. PubMed ID: 22819546
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.
    Granata R; Settanni F; Gallo D; Trovato L; Biancone L; Cantaluppi V; Nano R; Annunziata M; Campiglia P; Arnoletti E; Ghè C; Volante M; Papotti M; Muccioli G; Ghigo E
    Diabetes; 2008 Apr; 57(4):967-79. PubMed ID: 18162507
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of glucagon-like peptide-2 (GLP-2)-activated signaling pathways in baby hamster kidney fibroblasts expressing the rat GLP-2 receptor.
    Yusta B; Somwar R; Wang F; Munroe D; Grinstein S; Klip A; Drucker DJ
    J Biol Chem; 1999 Oct; 274(43):30459-67. PubMed ID: 10521425
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes.
    Hennige AM; Burks DJ; Ozcan U; Kulkarni RN; Ye J; Park S; Schubert M; Fisher TL; Dow MA; Leshan R; Zakaria M; Mossa-Basha M; White MF
    J Clin Invest; 2003 Nov; 112(10):1521-32. PubMed ID: 14617753
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SAD-A potentiates glucose-stimulated insulin secretion as a mediator of glucagon-like peptide 1 response in pancreatic β cells.
    Nie J; Lilley BN; Pan YA; Faruque O; Liu X; Zhang W; Sanes JR; Han X; Shi Y
    Mol Cell Biol; 2013 Jul; 33(13):2527-34. PubMed ID: 23629625
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.
    Lingohr MK; Dickson LM; McCuaig JF; Hugl SR; Twardzik DR; Rhodes CJ
    Diabetes; 2002 Apr; 51(4):966-76. PubMed ID: 11916914
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synergistic effect of dimethyl sulfoxide on glucagon-like peptide 1 (GLP-1)-stimulated insulin secretion and gene transcription in INS-1 cells: characterization and implications.
    Kemp DM; Habener JF
    Biochem Pharmacol; 2002 Aug; 64(4):689-97. PubMed ID: 12167488
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2.
    Jansson D; Ng AC; Fu A; Depatie C; Al Azzabi M; Screaton RA
    Proc Natl Acad Sci U S A; 2008 Jul; 105(29):10161-6. PubMed ID: 18626018
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.
    Zauli G; Milani D; Mirandola P; Mazzoni M; Secchiero P; Miscia S; Capitani S
    FASEB J; 2001 Feb; 15(2):483-91. PubMed ID: 11156964
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.