133 related articles for article (PubMed ID: 1284428)
1. Beta-lactams: a new class of conformationally-rigid inhibitors of gamma-aminobutyric acid aminotransferase.
Hopkins MH; Silverman RB
J Enzyme Inhib; 1992; 6(2):125-9. PubMed ID: 1284428
[TBL] [Abstract][Full Text] [Related]
2. Inactivation and inhibition of gamma-aminobutyric acid aminotransferase by conformationally restricted vigabatrin analogues.
Choi S; Silverman RB
J Med Chem; 2002 Sep; 45(20):4531-9. PubMed ID: 12238932
[TBL] [Abstract][Full Text] [Related]
3. Syntheses and evaluation of fluorinated conformationally restricted analogues of GABA as potential inhibitors of GABA aminotransferase.
Wang Z; Silverman RB
Bioorg Med Chem; 2006 Apr; 14(7):2242-52. PubMed ID: 16314106
[TBL] [Abstract][Full Text] [Related]
4. Inhibition and substrate activity of conformationally rigid vigabatrin analogues with gamma-aminobutyric acid aminotransferase.
Qiu J; Pingsterhaus JM; Silverman RB
J Med Chem; 1999 Nov; 42(22):4725-8. PubMed ID: 10579835
[TBL] [Abstract][Full Text] [Related]
5. A new class of conformationally rigid analogues of 4-amino-5-halopentanoic acids, potent inactivators of gamma-aminobutyric acid aminotransferase.
Qiu J; Silverman RB
J Med Chem; 2000 Feb; 43(4):706-20. PubMed ID: 10691696
[TBL] [Abstract][Full Text] [Related]
6. 4-(Oxoalkyl)-substituted GABA analogues as inactivators and substrates of GABA aminotransferase.
Burke JR; Silverman RB
J Enzyme Inhib; 1991; 5(3):199-205. PubMed ID: 1669447
[TBL] [Abstract][Full Text] [Related]
7. Fluorinated conformationally restricted gamma-aminobutyric acid aminotransferase inhibitors.
Lu H; Silverman RB
J Med Chem; 2006 Dec; 49(25):7404-12. PubMed ID: 17149870
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and evaluation of novel aromatic substrates and competitive inhibitors of GABA aminotransferase.
Clift MD; Silverman RB
Bioorg Med Chem Lett; 2008 May; 18(10):3122-5. PubMed ID: 17988865
[TBL] [Abstract][Full Text] [Related]
9. omega-Fluoromethyl analogues of omega-amino acids as irreversible inhibitors of 4-aminobutyrate:2-oxoglutarate aminotransferase.
Bey P; Jung MJ; Gerhart F; Schirlin D; Van Dorsselaer V; Casara P
J Neurochem; 1981 Nov; 37(5):1341-4. PubMed ID: 6795312
[TBL] [Abstract][Full Text] [Related]
10. Active site model for gamma-aminobutyrate aminotransferase explains substrate specificity and inhibitor reactivities.
Toney MD; Pascarella S; De Biase D
Protein Sci; 1995 Nov; 4(11):2366-74. PubMed ID: 8563634
[TBL] [Abstract][Full Text] [Related]
11. Time-dependent inhibition of gamma-aminobutyric acid aminotransferase, by 3-hydroxybenzylhydrazine.
Lightcap ES; Hopkins MH; Olson GT; Silverman RB
Bioorg Med Chem; 1995 May; 3(5):579-85. PubMed ID: 7648206
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and evaluation of novel heteroaromatic substrates of GABA aminotransferase.
Hawker DD; Silverman RB
Bioorg Med Chem; 2012 Oct; 20(19):5763-73. PubMed ID: 22944334
[TBL] [Abstract][Full Text] [Related]
13. Substrate stereospecificity and active site topography of gamma-aminobutyric acid aminotransferase for beta-aryl-gamma-aminobutyric acid analogues.
Silverman RB; Invergo BJ; Levy MA; Andrew CR
J Biol Chem; 1987 Mar; 262(7):3192-5. PubMed ID: 3818639
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis, and biological activity of a difluoro-substituted, conformationally rigid vigabatrin analogue as a potent gamma-aminobutyric acid aminotransferase inhibitor.
Pan Y; Qiu J; Silverman RB
J Med Chem; 2003 Dec; 46(25):5292-3. PubMed ID: 14640537
[TBL] [Abstract][Full Text] [Related]
15. 4-Amino-2-(substituted methyl)-2-butenoic acids: substrates and potent inhibitors of gamma-aminobutyric acid aminotransferase.
Silverman RB; Durkee SC; Invergo BJ
J Med Chem; 1986 May; 29(5):764-70. PubMed ID: 3701787
[TBL] [Abstract][Full Text] [Related]
16. Selective inhibition of gamma-aminobutyric acid aminotransferase by (3R,4R),(3S,4S)- and (3R,4S),(3S,4R)-4-amino-5-fluoro-3-phenylpentanoic acids.
Silverman RB; Nanavati SM
J Med Chem; 1990 Mar; 33(3):931-6. PubMed ID: 2308143
[TBL] [Abstract][Full Text] [Related]
17. Design of potential anticonvulsant agents: mechanistic classification of GABA aminotransferase inactivators.
Nanavati SM; Silverman RB
J Med Chem; 1989 Nov; 32(11):2413-21. PubMed ID: 2681782
[TBL] [Abstract][Full Text] [Related]
18. Inactivation of gamma-aminobutyric acid aminotransferase by various amine buffers.
Hopkins MH; Bichler KA; Su T; Chamberlain CL; Silverman RB
J Enzyme Inhib; 1992; 6(3):195-9. PubMed ID: 1284956
[TBL] [Abstract][Full Text] [Related]
19. Conformationally-restricted vigabatrin analogs as irreversible and reversible inhibitors of gamma-aminobutyric acid aminotransferase.
Pan Y; Calvert K; Silverman RB
Bioorg Med Chem; 2004 Nov; 12(21):5719-25. PubMed ID: 15465348
[TBL] [Abstract][Full Text] [Related]
20. Inhibitors of brain GABA aminotransferase.
Tunnicliff G
Comp Biochem Physiol A Comp Physiol; 1989; 93(1):247-54. PubMed ID: 2568226
[No Abstract] [Full Text] [Related]
[Next] [New Search]