BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

92 related articles for article (PubMed ID: 12844881)

  • 1. Immunoblot analysis and band depletion assays.
    Kaufmann SH; Svingen PA
    Methods Mol Biol; 1999; 94():253-68. PubMed ID: 12844881
    [No Abstract]   [Full Text] [Related]  

  • 2. Altered formation of topotecan-stabilized topoisomerase I-DNA adducts in human leukemia cells.
    Kaufmann SH; Svingen PA; Gore SD; Armstrong DK; Cheng YC; Rowinsky EK
    Blood; 1997 Mar; 89(6):2098-104. PubMed ID: 9058732
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction of apoptosis by topotecan: implications for the treatment of leukemia.
    Seiter K
    Semin Hematol; 1998 Jul; 35(3 Suppl 4):22-5. PubMed ID: 9779878
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effect of pyrazoloacridine (NSC 366140) on DNA topoisomerases I and II.
    Adjei AA; Charron M; Rowinsky EK; Svingen PA; Miller J; Reid JM; Sebolt-Leopold J; Ames MM; Kaufmann SH
    Clin Cancer Res; 1998 Mar; 4(3):683-91. PubMed ID: 9533538
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Liposomal encapsulation increases the activity of the topoisomerase I inhibitor topotecan.
    Subramanian D; Muller MT
    Oncol Res; 1995; 7(9):461-9. PubMed ID: 8835290
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional expression of human DNA topoisomerase I and its subcellular localization in HeLa cells.
    Mo YY; Wang P; Beck WT
    Exp Cell Res; 2000 May; 256(2):480-90. PubMed ID: 10772820
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The role of structural factors in the kinetics of cellular uptake of pyrazoloacridines and pyrazolopyrimidoacridines: implications for overcoming multidrug resistance towards leukaemia K562/DOX cells.
    Tarasiuk J; Majewska E; Seksek O; Rogacka D; Antonini I; Garnier-Suillerot A; Borowski E
    Biochem Pharmacol; 2004 Nov; 68(9):1815-23. PubMed ID: 15450947
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effective schedules of exposure of medulloblastoma and rhabdomyosarcoma xenografts to topotecan correlate with in vitro assays.
    Pawlik CA; Houghton PJ; Stewart CF; Cheshire PJ; Richmond LB; Danks MK
    Clin Cancer Res; 1998 Aug; 4(8):1995-2002. PubMed ID: 9717830
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Topotecan-triggered degradation of topoisomerase I is p53-dependent and impacts cell survival.
    Tomicic MT; Christmann M; Kaina B
    Cancer Res; 2005 Oct; 65(19):8920-6. PubMed ID: 16204064
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [Down-regulation of TopI by RNA interference reduces the drug-sensitivity of small cell lung cancer cell lines to topotecan].
    Liu XJ; Guo QS; Zhang Q; Song XR; Liu YL; Guo C
    Zhonghua Zhong Liu Za Zhi; 2008 Oct; 30(10):741-4. PubMed ID: 19173801
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reversal of MDR1-associated resistance to topotecan by PAK-200S, a new dihydropyridine analogue, in human cancer cell lines.
    Vanhoefer U; Müller MR; Hilger RA; Lindtner B; Klaassen U; Schleucher N; Rustum YM; Seeber S; Harstrick A
    Br J Cancer; 1999 Dec; 81(8):1304-10. PubMed ID: 10604726
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Flavopiridol binds to duplex DNA.
    Bible KC; Bible RH; Kottke TJ; Svingen PA; Xu K; Pang YP; Hajdu E; Kaufmann SH
    Cancer Res; 2000 May; 60(9):2419-28. PubMed ID: 10811119
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The mechanism of topoisomerase I poisoning by a camptothecin analog.
    Staker BL; Hjerrild K; Feese MD; Behnke CA; Burgin AB; Stewart L
    Proc Natl Acad Sci U S A; 2002 Nov; 99(24):15387-92. PubMed ID: 12426403
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The novel poly(ADP-Ribose) polymerase inhibitor, AG14361, sensitizes cells to topoisomerase I poisons by increasing the persistence of DNA strand breaks.
    Smith LM; Willmore E; Austin CA; Curtin NJ
    Clin Cancer Res; 2005 Dec; 11(23):8449-57. PubMed ID: 16322308
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Imatinib-resistant K562 cells are more sensitive to celecoxib, a selective COX-2 inhibitor: role of COX-2 and MDR-1.
    Arunasree KM; Roy KR; Anilkumar K; Aparna A; Reddy GV; Reddanna P
    Leuk Res; 2008 Jun; 32(6):855-64. PubMed ID: 18083230
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A phase I and pharmacological study of topotecan infused over 30 minutes for five days in patients with refractory acute leukemia.
    Rowinsky EK; Kaufmann SH; Baker SD; Miller CB; Sartorius SE; Bowling MK; Chen TL; Donehower RC; Gore SD
    Clin Cancer Res; 1996 Dec; 2(12):1921-30. PubMed ID: 9816150
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA topoisomerase I inhibitors.
    Takimoto CH; Kieffer LV; Arbuck SG
    Cancer Chemother Biol Response Modif; 1997; 17():80-113. PubMed ID: 9551210
    [No Abstract]   [Full Text] [Related]  

  • 18. Topotecan-induced topoisomerase IIalpha expression increases the sensitivity of the CML cell line K562 to subsequent etoposide plus mitoxantrone treatment.
    Chen S; Gomez SP; McCarley D; Mainwaring MG
    Cancer Chemother Pharmacol; 2002 May; 49(5):347-55. PubMed ID: 11976828
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amino- and glycoconjugates of pyrido[4,3,2-kl]acridine. Synthesis, antitumor activity, and DNA binding.
    Bouffier L; Baldeyrou B; Hildebrand MP; Lansiaux A; David-Cordonnier MH; Carrez D; Croisy A; Renaudet O; Dumy P; Demeunynck M
    Bioorg Med Chem; 2006 Nov; 14(22):7520-30. PubMed ID: 16879973
    [TBL] [Abstract][Full Text] [Related]  

  • 20. UVC inhibits HIF-1alpha protein translation by a DNA damage- and topoisomerase I-independent pathway.
    Rapisarda A; Melillo G
    Oncogene; 2007 Oct; 26(48):6875-84. PubMed ID: 17496931
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.