BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 12847090)

  • 1. Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter.
    Di Padova M; Bruno T; De Nicola F; Iezzi S; D'Angelo C; Gallo R; Nicosia D; Corbi N; Biroccio A; Floridi A; Passananti C; Fanciulli M
    J Biol Chem; 2003 Sep; 278(38):36496-504. PubMed ID: 12847090
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene.
    Lagger G; Doetzlhofer A; Schuettengruber B; Haidweger E; Simboeck E; Tischler J; Chiocca S; Suske G; Rotheneder H; Wintersberger E; Seiser C
    Mol Cell Biol; 2003 Apr; 23(8):2669-79. PubMed ID: 12665570
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Histone deacetylase inhibitor, Trichostatin A, activates p21WAF1/CIP1 expression through downregulation of c-myc and release of the repression of c-myc from the promoter in human cervical cancer cells.
    Li H; Wu X
    Biochem Biophys Res Commun; 2004 Nov; 324(2):860-7. PubMed ID: 15474507
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sp1 inhibits proliferation and induces apoptosis in vascular smooth muscle cells by repressing p21WAF1/Cip1 transcription and cyclin D1-Cdk4-p21WAF1/Cip1 complex formation.
    Kavurma MM; Khachigian LM
    J Biol Chem; 2003 Aug; 278(35):32537-43. PubMed ID: 12796485
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter.
    Nian H; Delage B; Pinto JT; Dashwood RH
    Carcinogenesis; 2008 Sep; 29(9):1816-24. PubMed ID: 18628250
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acetylation of histones associated with the p21WAF1/CIP1 gene by butyrate is not sufficient for p21WAF1/CIP1 gene transcription in human colorectal adenocarcinoma cells.
    Kobayashi H; Tan EM; Fleming SE
    Int J Cancer; 2004 Mar; 109(2):207-13. PubMed ID: 14750171
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter.
    Yokota T; Matsuzaki Y; Miyazawa K; Zindy F; Roussel MF; Sakai T
    Oncogene; 2004 Jul; 23(31):5340-9. PubMed ID: 15107822
    [TBL] [Abstract][Full Text] [Related]  

  • 8. p53-dependent down-regulation of telomerase is mediated by p21waf1.
    Shats I; Milyavsky M; Tang X; Stambolsky P; Erez N; Brosh R; Kogan I; Braunstein I; Tzukerman M; Ginsberg D; Rotter V
    J Biol Chem; 2004 Dec; 279(49):50976-85. PubMed ID: 15371422
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Increased expression of integrin beta1 subunit enhances p21WAF1/Cip1 transcription through the Sp1 sites and p300-mediated histone acetylation in human hepatocellular carcinoma cells.
    Fang Z; Fu Y; Liang Y; Li Z; Zhang W; Jin J; Yang Y; Zha X
    J Cell Biochem; 2007 Jun; 101(3):654-64. PubMed ID: 17211849
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line.
    Nakano K; Mizuno T; Sowa Y; Orita T; Yoshino T; Okuyama Y; Fujita T; Ohtani-Fujita N; Matsukawa Y; Tokino T; Yamagishi H; Oka T; Nomura H; Sakai T
    J Biol Chem; 1997 Aug; 272(35):22199-206. PubMed ID: 9268365
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The plant alkaloid cryptolepine induces p21WAF1/CIP1 and cell cycle arrest in a human osteosarcoma cell line.
    Matsui TA; Sowa Y; Murata H; Takagi K; Nakanishi R; Aoki S; Yoshikawa M; Kobayashi M; Sakabe T; Kubo T; Sakai T
    Int J Oncol; 2007 Oct; 31(4):915-22. PubMed ID: 17786325
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ICI182,780 induces p21Waf1 gene transcription through releasing histone deacetylase 1 and estrogen receptor alpha from Sp1 sites to induce cell cycle arrest in MCF-7 breast cancer cell line.
    Varshochi R; Halim F; Sunters A; Alao JP; Madureira PA; Hart SM; Ali S; Vigushin DM; Coombes RC; Lam EW
    J Biol Chem; 2005 Feb; 280(5):3185-96. PubMed ID: 15557281
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein.
    Koutsodontis G; Tentes I; Papakosta P; Moustakas A; Kardassis D
    J Biol Chem; 2001 Aug; 276(31):29116-25. PubMed ID: 11384995
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Silencing of transcription of the human luteinizing hormone receptor gene by histone deacetylase-mSin3A complex.
    Zhang Y; Dufau ML
    J Biol Chem; 2002 Sep; 277(36):33431-8. PubMed ID: 12091390
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression.
    Lagger G; O'Carroll D; Rembold M; Khier H; Tischler J; Weitzer G; Schuettengruber B; Hauser C; Brunmeir R; Jenuwein T; Seiser C
    EMBO J; 2002 Jun; 21(11):2672-81. PubMed ID: 12032080
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oncogenic STRAP functions as a novel negative regulator of E-cadherin and p21(Cip1) by modulating the transcription factor Sp1.
    Jin L; Datta PK
    Cell Cycle; 2014; 13(24):3909-20. PubMed ID: 25483064
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p53-independent induction of G1 arrest and p21WAF1/CIP1 expression by ascofuranone, an isoprenoid antibiotic, through downregulation of c-Myc.
    Jeong JH; Kang SS; Park KK; Chang HW; Magae J; Chang YC
    Mol Cancer Ther; 2010 Jul; 9(7):2102-13. PubMed ID: 20587660
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of the p21WAF1/CIP1 promoter independent of p53 by the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through the Sp1 sites.
    Huang L; Sowa Y; Sakai T; Pardee AB
    Oncogene; 2000 Nov; 19(50):5712-9. PubMed ID: 11126357
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Trichostatin A, a histone deacetylase inhibitor, activates the IGFBP-3 promoter by upregulating Sp1 activity in hepatoma cells: alteration of the Sp1/Sp3/HDAC1 multiprotein complex.
    Choi HS; Lee JH; Park JG; Lee YI
    Biochem Biophys Res Commun; 2002 Aug; 296(4):1005-12. PubMed ID: 12200149
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Histone deacetylase inhibitor activates the WAF1/Cip1 gene promoter through the Sp1 sites.
    Sowa Y; Orita T; Minamikawa S; Nakano K; Mizuno T; Nomura H; Sakai T
    Biochem Biophys Res Commun; 1997 Dec; 241(1):142-50. PubMed ID: 9405248
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.