These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
217 related articles for article (PubMed ID: 12851297)
1. Molecular genetics of human obesity-associated MC4R mutations. Lubrano-Berthelier C; Cavazos M; Dubern B; Shapiro A; Stunff CL; Zhang S; Picart F; Govaerts C; Froguel P; Bougneres P; Clement K; Vaisse C Ann N Y Acad Sci; 2003 Jun; 994():49-57. PubMed ID: 12851297 [TBL] [Abstract][Full Text] [Related]
2. Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans. Srinivasan S; Lubrano-Berthelier C; Govaerts C; Picard F; Santiago P; Conklin BR; Vaisse C J Clin Invest; 2004 Oct; 114(8):1158-64. PubMed ID: 15489963 [TBL] [Abstract][Full Text] [Related]
3. Intracellular retention is a common characteristic of childhood obesity-associated MC4R mutations. Lubrano-Berthelier C; Durand E; Dubern B; Shapiro A; Dazin P; Weill J; Ferron C; Froguel P; Vaisse C Hum Mol Genet; 2003 Jan; 12(2):145-53. PubMed ID: 12499395 [TBL] [Abstract][Full Text] [Related]
4. Functional characterization of melanocortin-4 receptor mutations associated with childhood obesity. Tao YX; Segaloff DL Endocrinology; 2003 Oct; 144(10):4544-51. PubMed ID: 12959994 [TBL] [Abstract][Full Text] [Related]
5. Differential regulation of cAMP-mediated gene transcription and ligand selectivity by MC3R and MC4R melanocortin receptors. Lee EJ; Lee SH; Jung JW; Lee W; Kim BJ; Park KW; Lim SK; Yoon CJ; Baik JH Eur J Biochem; 2001 Feb; 268(3):582-91. PubMed ID: 11168397 [TBL] [Abstract][Full Text] [Related]
7. Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene. Farooqi IS; Keogh JM; Yeo GS; Lank EJ; Cheetham T; O'Rahilly S N Engl J Med; 2003 Mar; 348(12):1085-95. PubMed ID: 12646665 [TBL] [Abstract][Full Text] [Related]
8. Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms. Yeo GS; Lank EJ; Farooqi IS; Keogh J; Challis BG; O'Rahilly S Hum Mol Genet; 2003 Mar; 12(5):561-74. PubMed ID: 12588803 [TBL] [Abstract][Full Text] [Related]
9. Poor cell surface expression of human melanocortin-4 receptor mutations associated with obesity. Nijenhuis WA; Garner KM; van Rozen RJ; Adan RA J Biol Chem; 2003 Jun; 278(25):22939-45. PubMed ID: 12690102 [TBL] [Abstract][Full Text] [Related]
10. Melanocortin 4 receptor mutations in a large cohort of severely obese adults: prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating. Lubrano-Berthelier C; Dubern B; Lacorte JM; Picard F; Shapiro A; Zhang S; Bertrais S; Hercberg S; Basdevant A; Clement K; Vaisse C J Clin Endocrinol Metab; 2006 May; 91(5):1811-8. PubMed ID: 16507637 [TBL] [Abstract][Full Text] [Related]
11. Signal pathway analysis of selected obesity-associated melanocortin-4 receptor class V mutants. Sharma S; Thibodeau S; Lytton J Biochim Biophys Acta Mol Basis Dis; 2020 Aug; 1866(8):165835. PubMed ID: 32423884 [TBL] [Abstract][Full Text] [Related]
13. Role of third intracellular loop of the melanocortin 4 receptor in the regulation of constitutive activity. Kim DH; Shin SW; Baik JH Biochem Biophys Res Commun; 2008 Jan; 365(3):439-45. PubMed ID: 17986382 [TBL] [Abstract][Full Text] [Related]
14. Point mutations in the melanocortin-4 receptor cause variable obesity in mice. Meehan TP; Tabeta K; Du X; Woodward LS; Firozi K; Beutler B; Justice MJ Mamm Genome; 2006 Dec; 17(12):1162-71. PubMed ID: 17143585 [TBL] [Abstract][Full Text] [Related]
15. Binge eating as a major phenotype of melanocortin 4 receptor gene mutations. Branson R; Potoczna N; Kral JG; Lentes KU; Hoehe MR; Horber FF N Engl J Med; 2003 Mar; 348(12):1096-103. PubMed ID: 12646666 [TBL] [Abstract][Full Text] [Related]
17. Functional characterization and structural modeling of obesity associated mutations in the melanocortin 4 receptor. Tan K; Pogozheva ID; Yeo GS; Hadaschik D; Keogh JM; Haskell-Leuvano C; O'Rahilly S; Mosberg HI; Farooqi IS Endocrinology; 2009 Jan; 150(1):114-25. PubMed ID: 18801902 [TBL] [Abstract][Full Text] [Related]
18. Cell surface expression of the melanocortin-4 receptor is dependent on a C-terminal di-isoleucine sequence at codons 316/317. VanLeeuwen D; Steffey ME; Donahue C; Ho G; MacKenzie RG J Biol Chem; 2003 May; 278(18):15935-40. PubMed ID: 12594226 [TBL] [Abstract][Full Text] [Related]
19. Engineering the melanocortin-4 receptor to control G(s) signaling in vivo. Srinivasan S; Vaisse C; Conklin BR Ann N Y Acad Sci; 2003 Jun; 994():225-32. PubMed ID: 12851320 [TBL] [Abstract][Full Text] [Related]
20. Identification of domains directing specificity of coupling to G-proteins for the melanocortin MC3 and MC4 receptors. Kim CS; Lee SH; Kim RY; Kim BJ; Li SZ; Lee IH; Lee EJ; Lim SK; Bae YS; Lee W; Baik JH J Biol Chem; 2002 Aug; 277(35):31310-7. PubMed ID: 12045190 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]