These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
164 related articles for article (PubMed ID: 12851320)
1. Engineering the melanocortin-4 receptor to control G(s) signaling in vivo. Srinivasan S; Vaisse C; Conklin BR Ann N Y Acad Sci; 2003 Jun; 994():225-32. PubMed ID: 12851320 [TBL] [Abstract][Full Text] [Related]
2. Structure activity studies of the melanocortin-4 receptor by in vitro mutagenesis: identification of agouti-related protein (AGRP), melanocortin agonist and synthetic peptide antagonist interaction determinants. Haskell-Luevano C; Cone RD; Monck EK; Wan YP Biochemistry; 2001 May; 40(20):6164-79. PubMed ID: 11352754 [TBL] [Abstract][Full Text] [Related]
3. Molecular determination of agouti-related protein binding to human melanocortin-4 receptor. Yang Y; Chen M; Lai Y; Gantz I; Yagmurlu A; Georgeson KE; Harmon CM Mol Pharmacol; 2003 Jul; 64(1):94-103. PubMed ID: 12815165 [TBL] [Abstract][Full Text] [Related]
5. Differential regulation of cAMP-mediated gene transcription and ligand selectivity by MC3R and MC4R melanocortin receptors. Lee EJ; Lee SH; Jung JW; Lee W; Kim BJ; Park KW; Lim SK; Yoon CJ; Baik JH Eur J Biochem; 2001 Feb; 268(3):582-91. PubMed ID: 11168397 [TBL] [Abstract][Full Text] [Related]
6. Conformation of the core sequence in melanocortin peptides directs selectivity for the melanocortin MC3 and MC4 receptors. Oosterom J; Nijenhuis WA; Schaaper WM; Slootstra J; Meloen RH; Gispen WH; Burbach JP; Adan RA J Biol Chem; 1999 Jun; 274(24):16853-60. PubMed ID: 10358030 [TBL] [Abstract][Full Text] [Related]
7. Differential Signaling Profiles of MC4R Mutations with Three Different Ligands. Paisdzior S; Dimitriou IM; Schöpe PC; Annibale P; Scheerer P; Krude H; Lohse MJ; Biebermann H; Kühnen P Int J Mol Sci; 2020 Feb; 21(4):. PubMed ID: 32059383 [TBL] [Abstract][Full Text] [Related]
8. Identification of domains directing specificity of coupling to G-proteins for the melanocortin MC3 and MC4 receptors. Kim CS; Lee SH; Kim RY; Kim BJ; Li SZ; Lee IH; Lee EJ; Lim SK; Bae YS; Lee W; Baik JH J Biol Chem; 2002 Aug; 277(35):31310-7. PubMed ID: 12045190 [TBL] [Abstract][Full Text] [Related]
9. Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans. Srinivasan S; Lubrano-Berthelier C; Govaerts C; Picard F; Santiago P; Conklin BR; Vaisse C J Clin Invest; 2004 Oct; 114(8):1158-64. PubMed ID: 15489963 [TBL] [Abstract][Full Text] [Related]
10. Substituted NDP-MSH peptides paired with mutant melanocortin-4 receptors demonstrate the role of transmembrane 6 in receptor activation. Fleck BA; Ling N; Chen C Biochemistry; 2007 Sep; 46(37):10473-83. PubMed ID: 17713970 [TBL] [Abstract][Full Text] [Related]
11. Engineering the melanocortin-4 receptor to control constitutive and ligand-mediated G(S) signaling in vivo. Srinivasan S; Santiago P; Lubrano C; Vaisse C; Conklin BR PLoS One; 2007 Aug; 2(7):e668. PubMed ID: 17668051 [TBL] [Abstract][Full Text] [Related]
13. Structural Complexity and Plasticity of Signaling Regulation at the Melanocortin-4 Receptor. Kleinau G; Heyder NA; Tao YX; Scheerer P Int J Mol Sci; 2020 Aug; 21(16):. PubMed ID: 32785054 [TBL] [Abstract][Full Text] [Related]
14. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands. Wilczynski A; Wang XS; Joseph CG; Xiang Z; Bauzo RM; Scott JW; Sorensen NB; Shaw AM; Millard WJ; Richards NG; Haskell-Luevano C J Med Chem; 2004 Apr; 47(9):2194-207. PubMed ID: 15084118 [TBL] [Abstract][Full Text] [Related]
15. Constitutive cholesterol-dependent endocytosis of melanocortin-4 receptor (MC4R) is essential to maintain receptor responsiveness to α-melanocyte-stimulating hormone (α-MSH). McDaniel FK; Molden BM; Mohammad S; Baldini G; McPike L; Narducci P; Granell S; Baldini G J Biol Chem; 2012 Jun; 287(26):21873-90. PubMed ID: 22544740 [TBL] [Abstract][Full Text] [Related]
16. Pharmacological characterization of 40 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists and the agouti-related protein (AGRP) antagonist. Xiang Z; Litherland SA; Sorensen NB; Proneth B; Wood MS; Shaw AM; Millard WJ; Haskell-Luevano C Biochemistry; 2006 Jun; 45(23):7277-88. PubMed ID: 16752916 [TBL] [Abstract][Full Text] [Related]
17. Cysteine residues are involved in structure and function of melanocortin 1 receptor: Substitution of a cysteine residue in transmembrane segment two converts an agonist to antagonist. Frändberg PA; Doufexis M; Kapas S; Chhajlani V Biochem Biophys Res Commun; 2001 Mar; 281(4):851-7. PubMed ID: 11237737 [TBL] [Abstract][Full Text] [Related]
18. Contribution of melanocortin receptor exoloops to Agouti-related protein binding. Yang YK; Dickinson CJ; Zeng Q; Li JY; Thompson DA; Gantz I J Biol Chem; 1999 May; 274(20):14100-6. PubMed ID: 10318826 [TBL] [Abstract][Full Text] [Related]
19. A single mutation in the 5-HT4 receptor (5-HT4-R D100(3.32)A) generates a Gs-coupled receptor activated exclusively by synthetic ligands (RASSL). Claeysen S; Joubert L; Sebben M; Bockaert J; Dumuis A J Biol Chem; 2003 Jan; 278(2):699-702. PubMed ID: 12441358 [TBL] [Abstract][Full Text] [Related]
20. Structural insight into the MC4R conformational changes via different agonist-mediated receptor signaling. Yang Y; Chen M; Dimmitt R; Harmon CM Biochemistry; 2014 Nov; 53(45):7086-92. PubMed ID: 25347793 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]